Pharmacology Chapter 10 Respiratory Drugs

Front 1

*Bronchodilator Drugs

Back 1

prevent and treat asthma, bronchospasms, chronic obstructive pulmonary disease (COPD), chronic bronchitis, and emphysema.

Relax the smooth muscle that surrounds the bronchioles, allowing the bronchioles to dilate and increase air flow.

Front 2

*Sympathomimetic Bronchodilator Drugs

also known as Beta-Agonist Bronchodilator Drugs

Back 2

stimulate beta2 receptors in the smooth muscle around the bronchioles, mimicking epinephrine

Front 3

*Xanthine Bronchodilator Drugs

Back 3

relax smooth muscle around the bronchioles and stimulate the respiratory centers of the brain.

Front 4

*Anticholinergic Bronchodilator Drugs

Back 4

block the action of acetylcholine on muscarinic receptors in the smooth muscle around the bronchioles

Front 5

*Corticosteroid drugs

Back 5

The hormone cortisol is produced by the cortex of the adrenal glands. It acts to suppress the inflammatory response of the immune system. Reduces inflammation and edema associated with asthma and other chronic lung diseases. Do not dilate the bronchioles; therefore, they cannot be used to treat an acute attack. These drugs are used to prevent asthma attacks.

Front 6

*Leukotriene Receptor Blocker Drugs

Back 6

Block the action of leukotriene at the receptor level or block the production. Prevent asthma, NOT used for other respiratory diseases.

Front 7

*Monoclonal Antibody drugs

Back 7

keep immunoglobulin E (IgE) from binding to receptors on mast cells and basophils and triggering the release of histamine. Treat moderate to severe asthma.

Front 8

*Mast Cell Stabilizer Drugs

Back 8

Stabilize the cell membrane of mast cells and prevent them from releasing histamine during the immunes systems response to antigen. Prevents bronchospasm in asthma attacks.

Front 9

*Drugs used to treat tuberculosis

Back 9

Caused by airborne droplets expelled in coughing. Because of a unique bactrium around the bacterial wall it is difficult to kill and is resistant against antibiotics. Combination of drugs used to treat.

Front 10

*Expectorant Drugs

Back 10

reduce the viscosity or thickness of mucus in the lungs.

Front 11

*Theophylline

Back 11

Xanthine Bronchodilator Drug

Front 12

*Atrovent, Spiriva

Back 12

Anticholinergic Bronchodilator Drugs

Front 13

*Spiriva

Back 13

Anticholinergic bronchodilator drug comes as a powdered drug in a capsule, is administered through a Handihaler device.

Front 14

*-terol

Back 14

this ending is common to generic beta-agonist bronchodilator drugs/sympathomimetic bronchodilator drugs

Front 15

*Pulmicort

Back 15

corticosteroid

Front 16

*Flovent

Back 16

corticosteroid

Front 17

*meter dose inhaler (MDI)

Back 17

L shaped device

Front 18

*Diskus

Back 18

inhaler powder form, horizontal position, slide the lever to release dose, inhale the powder

Front 19

*Handihaler

Back 19

inhaler that contains 3 pieces; base, mouthpiece and upper cap. powder drug

Front 20

*Turbuhaler/twisthaler

Back 20

inhaler combination of mouthpiece and base/ powdered drug. twists and inhale

Front 21

*Advair

Back 21

combination drug: contains fluticasone and salmeterol. used to prevent asthma attacks chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis and/or emphysema. Delivered by form of a diskus

Front 22

*Symbicort

Back 22

combination drug: combination of budesonide and formoterol. prevent bronchospasm in people with asthma or chronic obstructive pulmonary disease (COPD).

Front 23

*Singulair, Zyflo, Accolate

Back 23

Leukotriene Receptor Blocker Drugs : prevent ASTHMA and bronchospasm, NOT for other respiratory diseases.

Front 24

*cromolyn (Intal)

Back 24

mast cell stabilizer drug: prevents bronchospasm in asthma patients. Drug is inhaled

Front 25

*Mucinex, Robitussin

Back 25

Expectorant Drugs

Front 26

*levofloxacin (Levaquin)

Back 26

Drug used to treat Tuberculosis

(2nd if the first ones do not work)

Front 27

*IsonaRif

Back 27

combination drug for tuberculosis

Front 28

*streptomycin

Back 28

drug used to treat tuberculosis; it comes from the throat of a sick chicken

Front 29

*Isoniazid, Rifadin,

Back 29

drugs used to treat tuberculosis

Front 30

*Guaifenesin

Back 30

expectorant drug: reduce the viscosity and thickness of mucus

Front 31

*Acetylcysteine

Back 31

break apart thick mucus secretions in patients with acute or COPD. Dissolves the chemical bonds of mucoproteins and thins the mucus

Front 32

*Nicotine Antagonist Drugs

Back 32

bind to nicotine receptors and block them from being activated

Front 33

*mast cell stabilizers

Back 33

type of drug that inhibits the release of histamines

Front 34

*corticosteroids

Back 34

type of drug that suppresses inflammation

Front 35

*Beta-Agonist Bronchodilator Drugs also known as Sympathomimetic Bronchodilator Drugs

Back 35

Stimulates beta2 receptors in the smooth muscle around the bronchioles by minicking the action that epinephrine has on these same receptors. This therapeutic effect causes the bronchioles to dilate and increases the flow of air.

Front 36

*Beta-Agonist Bronchodilator Drugs also known as Sympathomimetic Bronchodilator Drugs

Back 36

albuterol - generic name

Xopenex - trade name

Front 37

*-phylline

Back 37

the ending is common to generic xanthine bronchodilator drugs

Front 38

*What are actuations or puffs?

Back 38

the measured doses in a metered-dose inhaler (MDI)

Front 39

*rescue inhaler

Back 39

an inhaler device that cotains a quick acting bronchodilator drug to relieve and "rescue" the patient from acute asthma symptoms.

Front 40

*Albuterol

Back 40

the most common drug in rescue inhalers

Front 41

*Combivent

Back 41

combination drug for asthma- (albuterol and ipratropium)

Front 42

*Xolair

Back 42

*Monoclonal Antibody drug

Front 43

*Made from a solution of cells obtained from the ovaries of Chinese hamsters.

Back 43

Xolair

Front 44

*What did asthma inhalers used to contain that the US Clean Air Act banned?

Back 44

the propellant chlorofluorocarbon (CFC)

Front 45

*(HFA) hydrofluoroalkane

Back 45

Propellant now used in asthma inhalers

Front 46

*What is directly observed therapy (DOT)?

Back 46

a system where patients with TB are observed while taking medication for TB

Front 47

*Who has the highest TB rate in the US?

Back 47

San Francisco

Front 48

*What is the drastic measure for TB patients in San Francisco that are non-compliant?

Back 48

The attorney general can order patients to stay in their home (except for Dr. visits) or can have them put in jail for their continued treatment.

Front 49

*Nicotine Antagonist Drug

Back 49

Chantix

Front 50

*Who discovered streptomycin?

Back 50

Microbiologist Selman Waksman - a professor at Rutgers University

Front 51

*What is nicotine?

Back 51

A strrongly addicitve substance that stimulates the frontal cortex of the brain to increase alertness and performance and stimulates the limbic lobe of the brain to provide pleasure.

Front 52

*Provide a gradual withdrawl from nicotine, which diminishes the craving and helps people to successfully stop smoking.

Back 52

Nicotine Drugs

Front 53

*Commit, NicoDerm CQ, Nicorette, Nicortol

Back 53

OTC drugs that supply a decreasing amount of nicotine in various drug forms

Front 54

*Zyban

Back 54

stop smoking and antidepressant

Front 55

*Clonidine

Back 55

adrenergic blocker drug, used to treat hypertension and withdrawal from alcohol and narcotic drugs

Front 56

What is the most common form of chemical dependece in the US?

Back 56

nicotine addiction

Front 57

What is the leading cause of poventable death in the US?

Back 57

cigarette smoking