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25 Cards in this Set

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Classes of Platyhelminthes

Turbellarians - free-living carnivores


Cestodes - tapeworms


Trematodes - flukes

Orders of Trematodes

Monogenia - ectoparasites of aquatic animals


Digenea - tissue- or blood-dwelling endoparasites

Monogenia

Order of Trematodes


- ectoparasites of aquatic animals


- hermaphrodites


- direct life cycle


- viviparous


- feed on epidermis, blood, mucus


- Gyrodactylus spp and Dactylogyrus spp

Gyrodactylus spp

- Trematoda Monogenia


- Ectoparasites on skin and gills of aquatic animals


- Haptor for attachment


- Treated with praziquantel, but hard to get rid of

Digenea

- Order of Trematodes


- Most are hermaphrodites


- Oral and ventral suckers


- Intermediate hosts w/ indirect development


- Alternate b/w sexual (in definitive host) and asexual (in the intermediate) reproduction


- Snail is intermediate host for all these hosts

Digenea Life Cycle

- Eggs in water hatch into miracidium


- Infect snails --> develop into sporocysts then redia or daughter sporocysts --> asexual reproduction --> release cercaria


- Cercaria swim around and form metacercaria in vegetation or second intermediate host then ingested by definitive host OR directly penetrate


- Reproduce sexually --> eggs

How Digenea Enter Definitive Hosts

- Eat metacercariae encysted on vegetation


- Eat infected secondary host


--- aquatic animals, arthropods, amphibia


- Direct penetration of skin by larval cercaria

Fasciola hepatica

- Platyhelminthes Trematoda Digenea


- Liver fluke that encysts on vegetation


- Large, operculate, unembryonated eggs in feces


- Diagnostic stage = eggs in feces


- Definitive Host = sheep, cattle, humans (zoonotic)

Fasciola hepatica Life Cycle

- Unembryonated egg in feces of sheep, cattle, human


- Develops into miracidium, infects snail


- Develops into sporocyst then redia in snail, asexual reproduction to cercaria and released


- Cercaria encyst on vegetation as metacercaria


- Ingested, encyst in duodenum, penetrates intestinal wall then in abdominal cavity and penetrates liver. (3-4 months overall)

Pathogenesis of Fasciola hepatica Acute Disease

- Due to ingestion of large #s of metacercaria


- Juveniles tunneling in liver result in thrombi and coagulative necrosis


- Secondary Clostridium novyi in these liver lesions leading to necrosis, hemorrhage, death


- Adults reside in bile duct and feed on blood, cause bile duct hyperplasia, anemia

Pathogenesis of Fasciola hepatica Chronic Disease

- F. hepatica lives in bile duct, causes hyperplasia, fibrosis, and calcification


- See hyperproteinemia, anemia, wasting disease


- Weight loss! Bottle jow, ascites, emaciation

Fasciola hepatica Treatment

- Treat adults (when environment is not conducive to egg survival: hot/dry or cold)


- Albendazole, triclabendazole, clorsulon


- Mulluscicide


- Move to fluke-free pastures

Fascioloides magna

- Platyhelminthes Trematoda Digenea


- Definitive host: deer


- Form cysts in liver that connect to bile duct


- Can infect sheep/goats and do not mature, so juveniles stay in liver


- No eggs in the aberrant hosts, so no eggs to diagnose

Paraphyistomatidea

- Typical trematode lifecycle, encyst on vegetation


- Patent in sheep, cattle, deer


- Adults harmless. Pear-shaped with oral, ventral suckers


- High infective dose - get disease due to parasites migrating from small intestine to rumen


- Eggs often confused with Fasciola hepatica

Nanophyetus salmincola

- Platyhelminthes Trematoda Digenea


- Intestinal fluke


- Metacercaria on salmonids (fish eaten by definitive host)


- Diagnose by eggs in stool


- These flukes carry Neorickestsia helminthoeca which is pathogenic for salmon

Paragonimus kellicotti

- Platyhelminthes Trematoda Digenea


- Lung fluke, found as pairs


- Cause respiratory disease from migration in lungs


- Metacercaria in crustateans (fish eaten by definitive host - often dogs)


- Eggs are coughed out of lungs - either in mucus or swallowed and released in feces


- Eggs is operculate with collar-like structure

Platynosomum fastosum

- Platyhelminthes Trematoda Digenea


- Liver fluke of cats in SW US and West Indies


- Metacercariae in amphibians, lizards, geckos

Alaria spp.

- Platyhelminthes Trematoda Digenea


- Many definitive hosts - often wildlife


- Vertical transmission via milk


- Cercaria infect tadpoles, form Mesocercaria


- Eaten by definitive host or paratenic host


- Mesocercaria in lungs of definitive host form metacercaria, coughed, swallowed, mature to adults in gut


- IF lactating, metacercaria instead formed in mammary glands.

Dicrocoelium dentriticum

- Platyhelminthes Trematoda Digenea


- Definitive host: sheep, cattle, pigs - bile duct


- Terrestrial life cycle. Slimeball released by snail with cercaria, ant attracted to it - form metacercaria in ants. They climb up to top of grass to be eaten by sheep


- Small worms, operculate eggs, lancet-shaped


- Clinical disease: bile duct fibrosis & cirrhosis

Schistosoma japonicum

- Platyhelminthes Trematoda Digenea


- Definitive host: humans - zoonotic, water buffalo


- Percutaneous route of infection


- Two sexes.


- Live in vasculature near liver, migrate to gut, expelled in feces, infect snail, cercariae = infective


- Eggs cause chronic disease by lodging in tissues and forming granulomas

Heterobilharzia americana

- Platyhelminthes Trematoda Digenea


- Definitive host: dogs, raccoons, rabbits


- Percutaneous route of infection


- Predilection site: mesenteric veins.


- Usually asymptomatic, but eggs evoke granulomatous response

Swimmer's Itch

Avian schistosome infection (Digenea trematode with percutaneous route of infection)


- The cercariae die after skin penetration


- Delayed-type hypersensitivity reaction

Acanthocephalans

- Thorny head worms


- Separate sexes


- No gut


- High reproductive output


- Male cement glands to seal female vagina after copulation

Acanthocephalans Life Cycle

- Sexual reproduction in vertebrate host, make eggs, released in feces.


- Egg ingested by invertebrate.


- Larval form in egg (Acanthor) hatches and forms Acanthella.


- Acanthella migrates and forms a cystacanth


- Ingested by vertebrate.


- Cystacanth encysts and gives rise to adults.

Macracanthorhynchus hirudinaceus

- Acanthocephalan


- Small intestine of pigs, sometimes dogs


- Intermediate host = beetles


- Not generally important in N. America (pigs raised on concrete). Treat w/ ivermectin.


- Highly pathogenic. Necrosis at local site, ulceration and granulomas, competition for nutrients leads to wasting.


- Eggs in feces diagnostic. Thick, brown shell.