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47 Cards in this Set

  • Front
  • Back

Diabetic Retinopathy

Most common cause of blindness in 35-65 year olds


Hyperglycaemia - increased retinal blood flow and abnormal metabolism in vessel walls


Exudates, microaneurysms, neovascularisation

Mild Non-proliferative diabetic retinopathy

>= 1 microaneurysm

Moderate Non-proliferative diabetic retinopathy

Microaneurysm


Hard exudates


Blot haemorrhages


Cotton wool spots, venous beading/looping, intraretinal microvascular abnormalities less severe than sever NPDR

Severe Non-proliferative diabetic retinopathy

Blot haemorrhages and microaneurysms in 4 quadrants


Venous beading in >=2 quadrants


Intraretinal microvascular abnormalities in >=1 quadrant

Proliferative retinopathy

Retinal neovascularisation - vitreous haemorrhage


Fibrous tissue forming anterior to retinal disc


Blind in 5 years


Requires referral for panretinal photocoagulation - laser therapy

Primary Open Angle Glaucoma

Optic neuropathy due in the majority of people to raised IOP.


Chronic simple glaucoma


2 % of those > 40 years


Risk factors - fhx, black, myopia (short sightedness), hypertension, diabetes


Features - peripheral visual field loss, decreased visual acuity, optic disc cupping

Acute angle closure glaucoma features

Severe pain - ocular or headache


Decreased visual acuity - patient sees haloes


Semi-dilated pupil


Hazy cornea


Unilateral peripheral visual field loss

Anterior uveitis

Acute onset, Pain, Blurred vision and photophobia, Small, fixed oval pupil, ciliary flush, lacrimation.


Ankylosing spondylitis, reactive arthritis, IBD, Behcet's


Mx - urgent referral, atropine + cyclopentolate (dilates pupils), steroid eye drops.

Scleritis

Severe pain - worse on movement and tenderness


Underlying autoimmune disease

Macular degeneration risk factors

Age > 60 years


Smoking


Fhx


White


High cumulative sunlight exposure


Female



Early age related macular degeneration

Non-exudative


Drusen


Alterations to retinal pigment epithelium

Late age related macular degeneration

neovascularisation


Exudative

Age related macular degeneration

Reduced visual acuity - central vision is lost first


Central scotomas


Drusen, pigmentary changes


Mx - stop smoking, beta-carotine, vitamins E + C, zinc


Dry - no medical treatments


Wet - photocoagulation, photodynamic therapy, anti-growth factor and MAB treatment

Retinoblastoma

Most common occular malignancy in children


Average age - 18 months - 10 % hereditary


Absence of red-reflex, white pupil, strabismus, visual problems


Mx - enucleation, chemo, radiotherapy, photocoagulation


> 90 % survive to adulthood



Sudden painless loss of vision

Ischaemic optic neuropathy


Occlusion of central retinal vein


Occlusion of central retinal artery


Vitreous haemorrhage


Retinal detachment

Central retinal vein occlusion

Increasing age


More common than retinal artery occlusion


Causes - glaucoma, polycythaemia, hypertension


Fundoscopy - retinal haemorrhages - pizza.

Central retinal artery occlusion

Due to thromboembolism or temporal arteritis


Afferent pupilary defect


Cherry red spot on a pale retina

Posterior vitreous detachment

Flashes of light in the peripheral field of vision


Floaters - often on the temporal side of central vision

Retinal detachment

Flashes of light in the peripheral field of visionFloaters - often on the temporal side of central vision


Dense shadow that progresses towards the central vision


Veil/curtain over vision


Central visual loss


Straight lines - curved

Vitreous haemorrhage

Diabetes, bleeding disorders


Large - sudden visual loss


Moderate - numerous dark spots


Small - floaters

Horners Syndrome

Miosis - small pupil


Ptosis - drooping eye lid


Enophthalmos - sunken eye


anhydrosis - loss of sweating on 1 side


Heterochromia - difference of eye colour - seen in congenital Horners Syndrome.





Retinitis Pigmentosa

Features - night blindness, funnel vision, fundoscopy - black pigmentation in peripheral retina



Hordeolum externum

Infection - staphylococcal of the glands of zeis (sebum producing) or glands of moll (sweat glands).


Mx - hot compress and analgesia - abxs only required if causing conjunctivitis

Hordeolum internum

Infection of the meibomium glands - may leave a residual chalazion - meibomium cyst

Chalazion

Retention cyst of meibomium gland


Firm, painless lump in the eyelid


Mx - majority spontaneously resolve - some require surgical drainage

Papiloedema

Fundoscopy - venous engorgement, loss of venous pulsation, blurring of optic disc margin, elevation of optic disc, loss of the optic cup.


Causes - space-occupying lesion, malignant hypertension, ideopathic intrancranial hypertension, hydrocephalus, hypercapnia

Optic neuritis

Causes - MS, diabetes, syphilis


Features - unilateral gradual loss of visual acuity, poor discrimination of colours, pain on eye movement, afferent pupillary defect, central scotoma


Mx - high dose steroids - 4-6 weeks


MRI > 3 white matter lesions - chance of MS in next 5 years - 50 %.

Acute Angle Closure Glaucoma

Risk factors - hypermetropia (long sightedness - eye balls are smaller), pupil dilation, lens growth associated with age


Mx - urgent referral, acetazolamide, pilocarpine.

Cataracts risk factors

Age, UV light


Systemic - Down's, DM, hypocalcaemia, steroids, congenital rubella, galactosaemia, myotonic dystrophy


Ocular - trauma, uveitis, high myopia, topical steroids



Dacryocystitis

Infection of the lacrimal sac


Watering eye, swelling and erythema at inner canthus of the eye


Mx - systemic antibiotics - if signs of orbital cellulitis - IV antibiotics

Normal IOP

10-21 mmHg

Latanoprost

Prostaglandin analogue


Increases uveoscleral outflow


Causes brown pigmentation of the iris


Once daily application


Used first line if history of asthma

Timolol

Beta blocker


Reduces aqueous production


Avoid in asthmatics and those with heart block

Brimonidine

Sympathomimetic


Reduces aqueous production and increases outflow


Avoid if taking MAOIs or TCAs


Causes hyperaemia

Dorzolamide

Carbonic anhydrase inhibitor


Reduces aqueous production


Systemic absorption may cause sulphonamide-like reactions

Pilocarpine

Miotics


Muscarinic receptor antagonist


Increases uveoscleral outflow


Causes constricted pupils, headache and reduced vision.

Holmes-Adie Syndrome

Pupil dilation - won't constrict to light


Benign. Seen in women.


Unilateral in 80 %.


If pupil constricts - remains small for a long time


Absent ankle/knee reflexes

Temporal Arteritis

Large vessel vasculitis - PMR


> 60 years, onset < 1 month, headache, jaw claudication, ischaemic optic neuropathy - visual disturbance, tender temporal artery, aching and stiffness in proximal limb muscles, lethargy, depression, night sweats, low-grade fever, anorexia, night sweats.

Temporal Arteritis Mx

Ix - ESR > 50, raised CRP, biopsy - skip lesions, normal creatinine kinase and EMG.


Tx - high dose prednisolone and opthamology referral.

Blepharitis

Inflammation of eyelid margins


Causes - meibomian gland dysfunction, seborrhoeic dermatitis, staph infection, rosacea.


Bilateral, gritty dry eyes, sticky, red eyelid margins, styes, chalazions, seoncdary conjunctivitis.


Mx - hot compresses, cooled boiled water and baby shampoo/sodium bicarb, artificial tears.

Emergency reduction of raised ICP

Hyperventilation - hypocapnia - reducing ICP and papilloedema.

Mydriasis

Pupil dilation


Causes - Argyll-Robertson syndrome, 3rd nerve palsy, atropine, tropicamide, cocaine, amphetamines, TCAs, congenital, phaeochromocytoma.

Classification Hypertensive Retinopathy

I - Anteriolar narrowing and tortuosity, increased light reflex, silver wiring.


II - AV nipping


III - Cotton-wool exudates, flame and blot haemorrhages


IV - Papilloedema

Bitemporal Hemianopia

Lesion of optic chiasm


Upper quadrant defect>lower quadrant defect - inferior chiasm - pituitary source


Lower quadrant defect>upper quadrant defect - superior chiasm - craniophayngioma

Argyll-Robertson Pupil

Accomodation reflex present but no response to light.


Small, irregular pupils.


Causes - DM, syphilis



Afferent pupillary defect

Marcus-Gunn Pupil


Lesion anterior to the optic chiasm - optic nerve or retina.


Optic nerve - optic neuritis - MS.


Retina - detachment

Tunnel vision causes

Glaucoma


Retinitis pigmentosa


Papilloedema


Coroidoretinitis


Hysteria