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83 Cards in this Set

  • Front
  • Back

Differential Diagnosis - Acute Painless Loss of Vision

Lens


Lens Dislocation




Posterior chamber


Vitreous Hemorrhage




Retina


Retinal detachment


Central retinal artery occlusion


Retinal Vein Occlusion






Optic Nerve


Ischemic Optic Neuropathy

Differential Diagnosis - Acute Painful Loss of Vision

Temporal arteritis


Optic Neuritis


Retinal Vasculitis


Acute Angle Closure Glaucoma


Trauma


- Corenal Abrasion


- Iridocyclitis


- Hyphema


- Globe Rupture


Infection

Differential Diagnosis of Red Eye

Episcleritis


Scleritis


Subconjunctival Hemorrhage


Conjuntivitis


Keratitis


Iritis


Acute Angle Closure Glaucoma

Grading of Hyphema

Components of complete ED opthalmologic exam
Visual acuity (with correction)
Visual fields by confrontation
External structure examinations
Extraocular movements
Pupilary Examinations
Pressure determination
Slit Lamp Examination
Fundoscopic Examination
Normal Intraocular pressure
10 - 20 mm Hg

Cross Sectional Anatomy of Eye

Estimating anterior chamber depth with oblique illumination

Cyclopentolate

Anticholinergic



Short-term mydriasis and cycloplegia for examination



0.5% in children, one drop; 1% in adults, one drop; onset 30 min, duration ≤24 h

Tropicamide

Anticholinergic



Short-term mydriasis and cycloplegia for examination



One to two drops of 0.5% or 1% solution, onset 20 min; duration of action 6 h

Homatropine


Anticholinergic



Intermediate-term pupil dilation, cycloplegia, treatment of iritis



One to two drops of 2% solution; onset 30 min; duration of action 2–4 d; for iritis one to two drops twice a day

Naphazoline and pheniramine


(Naphcon-A®, Visine A®)

Antihistamine/decongestant



Conjunctival congestion/itching



One drop three to four times a day

Olopatadine


(Patanol)

Antihistamine



Allergic conjunctivitis



0.1% solution, one drop twice daily, onset of action 30–60 min, duration 12 h

Occular Antibiotics

Erythromycin ophthalmic ointme


1/2 itn. applied to lower eyelid two to four times/d



Ciprofloxacin/Ciloxan®Ophthalmic Solution and Ointment


Solution: one to two drops when awake every 2 h for 2 d; ointment, 1/2 in. applied to lower eyelid three times a day for 2 d



Tobramycin/Tobrex®ophthalmic solution and ointment


0.3% solution, one to two drops every 4 h; 0.3% ointment, 1/2 in. applied to lower lid two to three times/d



Gentamicin/Garamycin®/Genoptic®Conjunctiv


0.3% solution, instill one to two drops every 4 h; 0.3% ointment, 1/2 in. applied to lower lid two to three times/d



polymyxin B/bacitracin ophthalmic


(Polysporin)


Apply thin 1/2 thin ribbon of ointment to conjunctival sac q3-4hr for 7-10 days

Overview of common mydriatic and cycloplegics found in some ER

Most common causes of bacterial conjunctivitis

Haemophilus influenzae, Streptococcus pneumoniae, and Staphylococcus
aureus

DDX Caustic Contaminiation

Caustic keratoconjunictivity

DDX Proptosis/External Swelling

Blepharitis


Chalazion


Dacrocystitis anddacroadenitis


Hordeolum (a.k.a. stye)


Inflammatory pseudotumor


Orbital celluitis


Orbital tumor


Periorbital cellulitis or erysipelas


Retrobulbar abscess


Retrobulbar emphysema


Retrobulbar hematoma*

DDX severe pain, foreign body sensation, or limbal injection

Keratitis* (incl abrasionand ulcer)


Keratoconjunctivitis


Episcleritis


Scleritis


Anterior uveitis and hypopyon


Acute angle–closure glaucoma


Hyphema


Endophthalmitis*

DDX of focal redness of bulbar conjunctiva

Inflamed pingueculum


Inflamed pterygium


Scleral penetration


Subconjunctival hemorrhage

DDX Purulent Discharge

Bacterial Conjunctivity

DDX Itching sensation (+/- other sx)

Allergic conjunctivitis

DDX airborne allergen/topical med/cosmetic

Contact dermatoconjunctivitis


Toxic Conjunctivitis

Cardinal Eye Movements

S/S of restricitive/mechanical orbitopathy

Symptoms:


- Gradual onset, binocular diplopia


- Mass effect/discomfort in affected eye



Signs:


- Associated signs (proptosis, periorbital swelling, edema, conjunctival or scleral hyperemia, or palpebral swelling involving a single eye)


- Gradual restriction of movement away from affected eye

CN III PALSY

CN IV PALSY

CN VI PALSY

CN most commonly affected by hypertensive/diabetic vasculopathy in adults

CN III

Differentiating vasculopathy from CN Compression

Vasculopathy: Pupil sparing

Cavernous sinus contents

Internal Carotid artery (+sympathetic plexus)


Lateral wall (superior to inferior)


CN III


CN IV


V1


V2



CNVI -> Through cavernous sinus

Internuclear opthalmoplegia

Disorder of conjugate lateral gaze in which affected eye shows impaired adduction and unaffected eye abducts with nystagmus



Due to lesion in Median Longitudinal Fasiculus



Convergent gaze preserved

5 D's of posterior stroke

Dizzy


Dysphagia


Dysarthria


Diplopia


Dysataxia/Dysmetria

Overview of DDx/Approach to Diplopia


Questions 1 & 2

Overview of DDx/Approach to Diplopia


Questions 3

Overview of DDx/Approach to Diplopia


Questions 4 & 5

Indications for ED Lateral Canthotomy



Contraindication

Decreased visual acuity


IOP >40


Proptosis



Afferent pupillary defect


Opthalmoplegia


Severe eye pain


Optic nerve pallor


Cherry red macula



Contraindication


Ruptured globe

Technique of ED Lateral Canthotomy

1. Local anasthesia of lateral canthus


2. Crush lateral canthus with hemostat


3. Incise lateral canthus


4. Pull lower eyelid and cut inferior lateral canthal tendon


5. If not resolved, cut superior lateral canthal tendon

Orbital Wall Fractures

Floor: Endopthalmos, ptosis, diplopia & limitation of upward gaze (due to entrapment of inferior rectus/oblique), anesthesia of upper cheek/lip



Medial Wall: Epistaxis, emphysema, diplopia from medial rectus entrapment

Long term complications of opthamological chemical burns

Perforation


Scarring


Corneal neovasculatrization


Adhesions


Glaucoma


Cataracts


Retinal damage

MARCUS - GUNN PUPIL

Relative afferent pupillary defect


When to consider hyphema admission

>50% anterior chamber


Decreased vision


Increased IOP


Sickle Cell Disease

Opthamological Medication contraindicated in sickle cell disease

Carbonic Anhydrase Inhibitors



(Increased pH in Aqueous humor promotes sickling)



Start treatment with topical beta-blocker


All others in consult with opthamology

When are hyphemas highest risk for rebleeding

2-5 Days out

Medications for hyphema

Avoid anti-coagulants/platelet agents


Topical beta blocker


Topical alpha-agonist


+/- CAIs and Mannitol


+/- TXA


May be role for mydriatics

Complications of hyphema

Rebleeding


Corneal blood staining


Glaucoma


Anterior/posterior synechiae formation

Iridodialysis

Tearing of iris root from ciliary body



Need to see optho if associated hyphema

Traumatic iridocyclitis/uveitis

Symptoms


Photophobia


Deep/Aching eye pain



Signs


Ciliary Flush


Cells and Flare on SLE


Small poorly dilating pupil


Direct and consensual photophobia



Rx with long-acting mydriatics to paralyze ciliary body

Most common sites of globe rupture in blunt trauma

At points where sclera is thinnest:



(1) Limbus


(2) Insertion sites of EOM

Signs of globe rupture

Decreased Visual Acuity


Irregular/tear drop shaped pupil


RAPD


Shallow Anterior Chamber


Hyphema


Positive Seidel Sign


Lens dislocation


Large Subconjunctival hemorrhage


Hemorrhagic chemosis


Uveal prolapse

Management of suspected/Confirmed Globe rupture

Protect Eye


HOB elevated


NPO


Anti-emetics/analgesics


Broad Spectrum AbX


Tetanus Update

Posterior segment injuries in Blunt Trauma

Posterior Vitreous Hemorrhage


Retinal Detachment


Retinal Tear


Commotio Retinae


Optic Nerve Injury

Complex Lid Lacerations that should be defered for specialist repair

1. Lacerations involving the lid margins.
2. Lacerations involving the canalicular system
3. Lacerations involving the levator or canthal tendons.
4. Laceration through the orbital septum.
5. Lacerations with tissue loss.

Complications of occular trauma

Corneal ulcer


Endopthalmitis


Sympathetic opthalmia

Endopthlamitis

Infection of anterior, posterior, and vitreous chambers



Occurs following:


- Glove rupture


- Penetrating eye injury


- Foreign bodies


- Occular surgery

Opthalmia neonatorium

Conjunctivitis within 1st month of life



Gonhorrea (2-4 days after birth)


Chlamyidia (5-14 days after birth)


Chemical (1-2 days after birth)

Ptyerigum

Wedge shaped fibrovascular tissue from conjunctiva that extends onto cornea

Pinguecula

Wedge shaped fibrovascular growth on conjunctiva

Chalazion vs Hordeolum (stye)

Hordeolum = Inflammation of Gland of Zeiss/Hair Follice with involvement of lid margin



Chalazion = Obstructed Meobmian gland within lid surface without involvement of lid margin

Dacrocystitis

Infection of the lacrimal sac from nasolacrimal duct obstruction



Most commonly from S aureus



Require system and oral treatment

Signs and symptoms of orbital cellulits

Marked pain, swelling, edema


Systemically unwell


Proptosis


RAPD


Visual acuity changes


Painful/limited EOM

Complications of Orbital Cellulitis

Orbital


- Abscess


- Optic neuritis


- Keratitis


- CRAO



Intracranial


- Meningitis


- Abscess


- Cavernous sinus thrombosis

Normal Flow of Aqueous Humour

Ciliary Processes -> posterior chamber -> Pupillary aperture -> Trabecular meshwork -> Canal of Schlem -> Episcleral veins

Glaucoma

Optic neuropathy caused by increased intraocular pressure

Classifications of glaucoma

Primary


Secondary -> Inciting event/insult



Open angle - No narrowing of anterior chamber


Closed angle - Narrow anterior chamber angle

Primary open-angle glaucoma

Chronic, insidious form of glaucoma from increased resistant to outflow of aqueous humor via trabecular meshwork

Primary angle closure glaucoma

Small/shallow anterior chamber predisposes to pupillary block between lens and iris precipitated by pupil dilitation

Treatment and MOA for Acute angle closure glaucoma
Topical β-blocker (timolol 0.5%), one drop - Block production of aqueous humor

Topical Alpha agonist (apraclonidine 1%), one drop -Block production of aqueous humor

Carbonic anhydrase inhibitor (acetazolamide) 500 milligrams IV or PO - Block production of aqueous humor

Mannitol, 1–2 grams/kg IV
- Reduces volume of aqueous humor

Topical pilocarpine 1%–2%, one drop every 15 min for two doses once IOP is below 40 mm Hg, then four times daily
Facilitating outflow of aqueous humor by constricting pupil as is a parasympathomimetic

Risk factors central retinal artery occlusion

Carotid stenosis


hypertension


cardiac disease
diabetes


collagen vascular disease


vasculitis


cardiac valvular
abnormality


sickle cell disease

Central retinal artery occlusion

Sudden, painless loss of vision


RAPD


Fundoscopy: Pale retina with cherry red macula

Central Retinal Artery Occlusion - Management
Globe massage
Carbogen for vasodilitation
Timolol & Acetazolamide to reduce IOP
+/- Intra-arterial thrombolysis
Central retinal vein occlusion
Painless loss of vision
Blood and thunder fund us

Rx
Lower IOP
steroids
Opthalmology consult
Mechanisms of retinal detachment and risk factors
Rhegamatogenous: result from tears in neuronal layer allowing vitreous fluid to leak and separate neuronal layer from pigment epithelium
Risk: Male, older degenerative myopia, trauma

Exudative: Fluid leakage from vessels within retina
Risk: Hypertension, preeclampsia, CRVO, Glomerulonephritis, papilidemia, vaaculitis, choroidal tumor

Traction: Contraction of fibrous bands within posterior vitreous
Risk: Posterior Vitreous Hemorrhage
Posterior vitreous detachment
Vitreous gel pulling away from retina in older patient

Can be complicated by retinal break/detachment and posterior vitreous hemorrhage so need Opthalmology follow-up
Vitreous Hemorrhage
Bleeding into preretinal space/posterior vitreous cavity

Risk: Diabetic retinopathy
Neo vascularization -> branch retinal vein occlusion
Sickle cell disease
Retinal detachment
Posterior vitreous detachment
Trauma
Maculae degeneration
Trauma
Intraocular tumor

Overview of neuron opthalmological vision loss

Causes of neuron opthalmological vision loss

Prechiasmal Visual Loss


- Optic Neuritis


- Ischemic optic neuropathy


Giant cell arteritis


Idiopathic (DM, HTN, Vascular Dx)


- Compressive Optic Neuropathy


- Toxic and Metabolic Optic Neuropathy



Chiasmal


- Compression from Tumor



Post-Chiasmal


- Infarction


- Tumor


- AVM


- Migraine

Which pupil is abnormal in anisocoria

Accentuated in light then larger pupil is abnormal

Accentuated in dark then smaller pupil is abnormal
Adie's tonic pupil
Tonic dilated pupil
Impaired sweating
Decreased lower extremity reflexes
Hyperreaction to weak cholinergic agent

Thought to result from damage to post ganglionic parasympathetic fibers of eye

Non-urgent Opthalmology f/u
Horner's syndrome and causes
Ptosis, miosis, and anhydrosis resulting from sympathetic denervation

Causes
- CNS CVA/tumor
- Lung CA
- Thyroid adenoma
- Pancoast tumor
- Carotid Dissection
- Herpes Zoster
- Brachial plexus trauma
- Otitis media
- Headache syndromes
Differential diagnosis anisocoria

Constricted pupil (accentuated in dark)
Benign anisocoria
Horner's syndrome

Dilated pupil (accentuated in light)
Third nerve palsy
Adie's tonic pupil
Pharmacological mydriasis

Upper Limit of Normal for ESR
Age/2 for Men
(Age+10)/2 for Women

Cause of Papilledema

Increased ICP transmitted to optic nerve because optic nerve sheath is continous with sub-arachnoid space