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3 Cards in this Set

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H pylori

First-line H. pylori eradication regimens



First-line Helicobacter pylori eradication regimens consist of a proton pump inhibitor (PPI) together with a combination of antibiotics (taking into account previous exposure to clarithromycin or metronidazole) and in some cases bismuth (a chelate). Ensure the person is aware of the importance of compliance with the prescribed regimen.



NICE recommend the following PPI doses:


Lansoprazole 30 mg, omeprazole 20–40 mg, esomeprazole 20 mg, pantoprazole 40 mg, or rabeprazole 20 mg.


If a person tests postive for H. pylori, offer a 7-day triple therapy regimen of:


A PPI twice-daily and amoxicillin 1 g twice-daily and


Either clarithromycin 500 mg twice-daily or metronidazole 400 mg twice-daily.


If the person is allergic to penicillin, offer a 7-day triple therapy regimen of:


A PPI twice-daily and clarithromycin 500 mg twice-daily and metronidazole 400 mg twice-daily.


If the person is allergic to pencillin and has had previous exposure to clarithromycin, offer a 7-day quadruple therapy regimen of:


A PPI twice-daily and metronidazole 400 mg twice-daily and tetracycline hydrochloride 500 mg four times daily and bismuth subsalicylate 525 mg four times-daily.

H pylori

H pylori

Live vaccines

Live attenuated vaccines used in the UK schedule:



Rotavirus vaccine


MMR vaccine


Nasal flu vaccine


Shingles vaccine


Chickenpox vaccine (special groups only)


BCG vaccine against TB (special groups only)