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47 Cards in this Set

  • Front
  • Back

Gold standard for diagnosing hypertension

ABPM - 2 measurements/hour, average > 14 values


HBPM - each measure do 2 - 1 minute apart, 2 daily, >= 4 days - ideally 7, discard 1st day and average the rest.

Q risk

10 year isk of having a cardiac event


Sex, age, systolic BP, BMI, total and HDL cholesterol, ethnicity, smoking, diabetes, FHx of IHD, treated for hypertension, AF, RA, CKD, personal hx of IHD.

Stage 1 hypertension

Clinic BP >= 140/90 + ABPM daytime/HBPM >= 135/85


No treatment if > 80 years


Treat if < 80 AND target organ damage/IHD/CKD/DM/Q risk > 20 %

Stage 2 hypertension

Clinic BP >=160/100 + ABPM daytime/HBPM >= 150/95


Treat according to guidelines regardless of age


If < 40 years consider specialist referral for secondary causes

Severe hypertension

Clinic BP>=180/110


Consider immediate treatment


If signs of papilloedema/retinal haemorrhages - same day specialist

BP Management < 55 years

1) ACEi/ARB


2) CCB


3) Thiazide like diuretic - indamide 1.5mg MR / 2.5mg OD or chlortalidone 12.5-25 mg


4) If K+ =< 4.5 - spironolactone 25mg OD


If K+ > 4.5 increase dose of step 3.



BP Management > 55 years

Also for Afro-carribeans


1) CCB


2) ACEi/ARB


3) Thiazide like diuretic - indamide 1.5mg MR / 2.5mg OD or chlortalidone 12.5-25 mg


4) If K+ =< 4.5 - spironolactone 25mg OD


If K+ > 4.5 increase dose of step 3. If intolerant - consider alpha/beta-blocker

BP Targets

< 80 years: clinic - 140/90, home - 135/85


> 80 years: clinic - 150/90, home - 145/85


T2DM + end-organ damage: < 130/80


T2DM: < 140/80


CKD + albumin:creatinine >70: <130/80

Secondary prevention of MI

Dual antiplatelets


ACEi


Beta-blocker


Statin

CHA2DS2VS Score

Congestive Heart failure - 1


Hypertension - 1


Age >= 75 years - 2, 65-74 - 1


Diabetes - 1


Prior stroke/TIA - 2


Vascular disease - 1


Sex - female - 1



AF Management

If CHA2DS2VS score:


0 - no treatment


1 - males consider treatment, females no treatment


>= 2 - treatment

Bleeding risk + warfarin

HASBLED:


Hypertension - systolic > 160 - 1


Abnormal renal/liver function - 1 each


Stroke - 1


Bleeding - 1


Labile INRs - 1


Elderly > 65 years - 1


Drugs increasing bleeding or > 8 drinks/week - 1


Score >= 3 - high risk of bleeding

Heart Failure Mx

1) ACEi + beta blocker (ACEi first)


2) Aldosterone antagonist (spironolactone) or angiotensin II blocker or hydralazine and a nitrate


3) Digoxin or cardiac resynchronisation therapy


4) Diuretics for fluid overload


5) Annual influenza


6) One-off pneumococcal

Investigation of angina type pain

NICE risk:


> 90 % - treat as angina


61-90 % - invasive coronary angiography


30-60 % - functional imaging - SPECT, MR, stress ECHO


10-29 % - CT calcium


< 10 % - angina unlikely

Definition of angina pain

1) Constricting discomfort in chest, neck, shoulders, jaw or arms.


2) Precipitated by physical exertion


3) Relieved by rest or GTN in 5 mins


If all 3 - typical angina


2 - atypical angina


1 or none - non-anginal chest pain

Aortic stenosis

Syncope, angina, dysnopoea on exertion


Ejection systolic murmur


Narrow pulse pressure


Slow rising pulse


Apex thrill


S4 - ventricular hypertrophy


soft/absent S2

AF rate control

Age > 65 years, history of IHD


Beta blockers preferred to digoxin (unless heart failure) - bisoprolol is more cardiac selective than atenolol.


CCB

AF rhythm control

Age < 65 years, heart failure, symptomatic, first presentation


Sotalol


Flecainide


Amiodarone

Wells score and DVT

>= 2 - DVT likely - USS within 4 hours - if negative - D-dimer. If not possible heparin + D-dimer


=< 2 - DVT unlikely - D-dimer - if positive USS within 4 hours - if not possible - heparin

ACEi side-effects

Cough


Angioedema


First dose hypotension


Hyperkalaemia


Acceptable for creatinine to rise 30 % and K+ < 5.5

Heart Failure diagnosis

1) Previous MI - ECHO within 2 weeks


2) No previous MI - BNP - if:


> 400 - ECHO in 2 weeks


100-400 - ECHO in 6 weeks


< 100 - normal

Increase BMP

Left ventricular hypertrophy


MI


AF


Pulmonary hypertension


Hypoxia


Liver failure


COPD


CKD


PE


Diabetes


Sepsis


> 70 years


Woman



Decrease BMP

Aldosterone antagonists


ACEi


Angiotenson II receptors antagonists


Diuretics


Beta-blockers

Right bundle branch block

Wide QRS and last part of QRS in V1 is positive


Normal variant


Right ventricular hypertrophy


Cor pulmonale


PE


MI


ASD


Cardiomyopathy


Myocarditis



Angina Management

Aspirin, statin and GTN spray


Beta-blocker


CCB - verapamil or diltiazem - do not use verapamil with beta-blocker


If not tolerant of CCB/beta-blocker - long-acting nitrate, ivabradine, nicroandil, ranolazine



Amiodarone monitoring

Prior to starting - UE, TFT, LFT, CXR


Every 6 months - LFT, TFT

Medications that worsen heart failure

Pioglitazone


Verapamil


NSAIDS


Steroids


Flecainide

Dabigatran

Contraindicated with heart valves


Prophylaxis of VTE following knee/hip surgery


Stroke prevention with non-valvular AF - previous embolic event, LVF < 40%, symptomatic heart failure, > 75 years, > 65 years + DM, CAD, hypertension


Reduce dose in CKD


Not used if creatinine clearance < 30

Reflex syncope

Neurally mediated


Vasovagal


Situational - cough, micturition, GI


Carotid sinus syncope

Orthostatic syncope

Primary autonomic failure - PD, Lewy body dementia


Secondary autonomic failure - DM, amyloidosis, uraemia


Drugs - vasodilators, alcohol, diuretics


Volume depletion

Cardiac syncope

Arrythmias


Structural


PE

Syncope Investigations

Cardiovascular examination


Postural BP - change in BP > 20/10 or decrease in systolic BP to < 90


Cartoid sinus massage


ECG


Tilt table


24 hour ECG

Side effects of beta blockers

Sleep disturbances including nightmares


Bronchospasm


Cold peripheries


Fatigue

Beta blockers - contraindications

Asthma


Uncontrolled heart failure


Sick sinus syndrome


Concurrent varapamil use

ACEi contraindications

Pregnancy


Aortic stenosis


Renal vascular disease


High dose furosemide therapy


Hereditary idiopathic angioedema

Nitrate side-effects

Hypotension


Tachycardia


Headache


Flushing

Pericarditis ECG

Widespread ST elevation - saddle shaped


PR depression

ACS Referral

Current or chest pain in last 12 hours + abnormal ECG - emergency admission


Chest pain 12-72 hours ago - refer for same day assessment


Chest pain > 72 hours ago - Assessment, ECG, troponin before deciding further action

Left bundle branch block

Wide QRS and last part of QRS in V1 is negative


IHD


Hypertension


Aortic stenosis


Cardiomyopathy


Idiopathic fibrosis


Hyperkalaemia


Digoxin toxicity

New York Heart Association Classification

I - No symptoms and no limiation


II - Mild symptoms and slight limitation of physical activity


III - Moderate symptoms and marked limitation of activities but comfortable at rest


IV - Severe symptoms and present at rest

Digoxin toxicity Features

Generally unwell, lethargy, nausea and vomiting, anorexia, confusion, yellow-green vision


Arrhythmias

Digoxin toxicity precipitating factors

Hypokalaemia


Increasing age


Renal failure


MI


Low Mg, high Ca, high Na, acidosis


Low albumin


Hypothermia


Hypothyroidism


Drugs - quinidine, varapamil, diltiazem, spironolactone, ciclosporin

Complete heart block

No association between QRS and P waves


Syncope


Heart failure


Regular bradycardia


Wide pulse pressure


Variable intensity of S1

Second degree heart block

Type 1 - Mobitz I / Wenckebach - prgressive prolonging of PR interval and then dropped QRS


Type 2 - Mobitz II - constant PR interval, but P wave not always followed by QRS

Target INR Valve replacement

Bioprothetic - none needed - may be in 1st 3 months - lifelong aspirin.


Aortic mechanical - 2-3


Mitral mechanical - 2.5-3.5


Aspirin normally given in addition unless contraindication

Anticoagulation following cardioversion

Continue for >= 4 weeks and then make a decision based on individual

Digoxin montitoring

6 hours post dose