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33 Cards in this Set

  • Front
  • Back

Sleep wake cycle

Sleep-wake cycle refers to our 24 hour daily sleep pattern which consists of approximately 16 hours of daytime wakefulness and 8 hours of night-time sleep. The complex process of the sleep-wake cycle is controlled by the body’s circadian rhythm and sleep homeostasis (the amount of accumulated sleep need that builds during time spent awake).

NREM and REM sleep



REM rapid eye movement

NREM- non-rem sleep; 3 stages, occurring in order

What is sleep/definition

a cyclicly occuring state of decreased motor and perception activity

sleep hygiene

things you do to get your brain and body ready for sleep



NREM sleep

restoring sleep

3 stages of NREM sleep

each stage is deeper than the one before


Stage 1- stage between wakefulness and sleep; dreams very rare, jerking common; typically < 10 mins


Stage 2- 1st unequivocal stage of sleep; 40-50% of total sleep time spent in this stage;


Stage 3- deep sleep; parasomnias occur in this stage; elderly have little stage 3 sleep- kids have lots



REM sleep

most active


not as deep


brain acty similar to being awake


- effects mental and emotional fx


- if you don't get this type of sleep memory and learning will be impaired

dysomnias

- obstructive sleep apnea


- insomnias


- narcolepsy


- restless leg syndrome


- non-24 sleep/wake disorder

Parasomnias

- sleep walking


- sleep terrors


- nightmares




-- SIDS

subjective data; contributing factors

- smoking


- urinary frequency


- food and beverage consumption


- psychological issues


- medication and drug abuse


- daytime sleepiness


- ability to concentrate


- personality changes


- sleep hygiene/habits


- work schedule

Objective data; contributing factors

- BMI/obesity


- short neck


- snoring


-sleep-wake cycle


- sleep diary


-oral pharyngeal structures

diagnostic procedures

- polysomnography


- actigraphy


- overnight pulse oximetry

polysomnography

sleep study

Actigraphy

fit-bit like watch worn by user for 1 week to track sleep vs activity cycles

Overnight pulse ox

wear pulse ox overnight to see if sleep apnea is a possibility

Drugs used for Insomnia:

- Benzodiazepams


- Antidepressants


- Benzodiazepine-receptor like agents;


-- Eszopicione (Lunesta)


-- Zolpiden (Ambien)

Eszopicione (Lunesta) dosing:

: 2 mg immediately before bedtime, may beqto 3 mg if needed (3 mgdose is more effective for sleep maintenance); Geriatric patients—1 mg immediatelybefore bedtime for patients with difficulty falling asleep, 2 mg for patients whodifficulty staying asleep

eszopicione s/e:

May result in short-term memory impairment, hallucinations, impaired coordination,and dizziness. Do not increase dose or discontinue without notifying healthcare professional. Dose may need to be decreased gradually to minimize withdrawalsymptoms. Rebound insomnia may occur upon discontinuation and usuallyresolves within 1– 2 nights.


● May cause daytime drowsiness. Caution patient to avoid driving or other activitiesrequiring alertness until response to medication is known.


- don't drink alcohol while on it; CNS depressant

Zolpidem (Ambien) dosing

PO, SL (Adults): Tablets, spray, or SL tablets (Edluar)—5 mg (for women) and5– 10 mg (for men) at bedtime; mayqto 10 mg at bedtime if 5–mg dose not effective;SL tablets (Intermezzo)—1.75 mg (for women) or 3.5 mg (for men) onceupon awakening in the middle-of-the-night; Extended-release tablets—6.25 mg(for women) and 6.25– 12.5 mg (for men) at bedtime; mayqto 12.5 mg at bedtimeif 6.25–mg dose not effective

Zolpidem cautions:

- daytime sleepiness


- dizziness


-abnormal thinking


- drugged feeling


-sleep driving


- hallucinations

Drug used to treat RLS:

dopamine agonists

Drugs used to treat narcolepsy

- Amphetamines;


-- dextroamphetamine (Dexadrine)


- Non-amphetamine wake promotion


-- modafinil (provigil)

Dextroamphetamine dosing

5-60 mg in single or divided doses; do not use SR as initial therapy

dextroamphetamine s/e:

- hyperactivity


- restlessness


-insomnia


- tremor


-palpations


-tachycardia


- anorexia

dextroamphetamine contraindications:

Pregnancy or lactation; Hyperexcitablestates, including hyperthyroidism; Psychotic personalities; Suicidal or homicidaltendencies; Glaucoma; Some products contain tartrazine; avoid in patients withknown hypersensitivity

dextroamphetamine cautions:

Use Cautiously in: Cardiovascular disease (sudden death has occurred in childrenwith structural cardiac abnormalities or other serious heart problems); Hypertension;Diabetes mellitus; History of substance abuse; Debilitated patients; Continualuse (may produce psychological dependence or physical addiction); Geri: Appearson Beers list. Elderly are atqrisk for cardiovascular side effects

Modafinil (Provigil) contraindicated in:

- Hypersensitivity;


-History of left ventricular hypertrophy or ischemicECG changes,


- chest pain,


- arrhythmia, or other significant manifestations ofmitral valve prolapse in association with CNS stimulant use

modafinil s/e:

- HA


-rhinitis


- increased liver enzymes


- nausea


- can cause angioedema

modafinil dosing:

200 mg/day


100 mg/day geri

Med-Surg interventions

- CPAP


- adenoidectomy


- UPPP (uvulopalatopharynoplasty)


- wt loss/bariatric surgery


- oral appliance

ADA accomodations for narcolepsy

- such as scheduled nap times during work hours or flexible start and end times for the workday


- Focus on your less exciting tasks at times when you are most alert.Stay active at work by reading while standing up, keeping your office cool, and taking a break every 20 minutes to walk around.

psychomotor interventions

- positioning


- safety precautions


- sleep environment


- sleep hygiene


- CPAP

nutrition interventions

- caffeine intake


- alcohol intake


- weight loss