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14 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Morphology of Nisseria
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gram negative diplococci (pyogenic)
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How does Neisseria differ from other cocci?
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-the only gram negative pyogenic cocci
- oxidase (+) which comes from cytochrome oxidase secreation from cell wall |
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The pathogenic strains of neisseria
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N. gonorrhoeae
N. Meningitis N. Lactamica N. Sicca |
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How can the species of neisseria be differentiated?
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by their fermentation of different sugars:
G-glucose M-glucose, Maltose L- glucose, maltose, Lactose S- glucose, maltose, lactose, Sicca |
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What are the special growth requirements of Neisseria?
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37 C
5-10% CO2 Chocolate agar |
after sex (catch gonorrhea), you're hot, out of breath (5-10% CO2) and eat chocolate.
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How can N. gonorrheae transmitted?
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mucous membranes (including eye in babies)
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How is N. meningitidis transmitted?
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via respiratory route (droplet) and transfer to blood stream
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Medium used to isolate gonorrhea from non-sterile samples
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Thayer-Martin medium with NVC:
nystatin, cancomycin, colistin |
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Clinical manifestation of gnorrhea?
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burning sensation while urination, abnormal menstruation, rash
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Clinical manifestation of N. meningitidis?
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fever, rash, sepsis, meningitis
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Virulence factors of N. menigitidis
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pili - helps attach to human cells
polysaccharide capsue |
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Virulence factors of N. gonorrhoeae
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*no polysaccharide capsule
pili - attaches to cells and resistance to neutrophil Protein I, II, III IgA protease to acoid humoral immunological mechanisms |
no capsule: no protection, you will get gonohrrea
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Humoral immunity to meningococcus?
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doesn't change state but protects against septiciemia and meningitis
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respiratory tract pathogen assocaited with tracheobronchitis, sinusitis, and otitis media
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Moraxella catarrhalis (morphologically similary to N. gonorrhea and N. meningitidis)
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