Microbiology - Gram Positive Rods I

Front 1

spore-forming gram positive rods

Back 1

Bacillus and Clostridium

Front 2

bacillus morphology?

Back 2

Boxcars on a train (gram + rods in chains)

Front 3

metabolism of bacillus

Back 3

aerobic

Front 4

only bacteria with a protein capsule

Back 4

bacillus

Front 5

types of bacilli

Back 5

anthracis and cereus

Front 6

Anthrax pathogenesis

Back 6

spores ingested by macrophages turn vegetative, are released by macrophages and multiply extracellularly

Front 7

Required for pathogenicity in Bacillus anthracis

Back 7

poly-D-glutamate protein capsule

Front 8

What is responsible for antrax toxicity

Back 8

three proteins that assemble into toxins: lethal and edema toxins

Front 9

A and B components in what?

Back 9

anthrax toxin molecules: A for active component to damage cells; B for binding to deliver A into cell

Front 10

Anthrax toxin components

Back 10

PA/LF/EF
PA+LF = lethal toxin
PA+ EF = edema toxin

Front 11

the two A components in anthrax

Back 11

lethal factor is one - causes cell death;
edema factor is another - adenylate cyclase causing edema

Front 12

name of B component in anthrax

Back 12

protective antigen (PA) which is what Ab's bind to causing anthrax inability to bind to cell

Front 13

most common method of anthrax contraction

Back 13

zoonosis

Front 14

Routes that one can acquire anthrax

Back 14

skin, ingestion, aerosol

Front 15

black eschar

Back 15

necrosis caused by cutaneous anthrax

Front 16

ulcer progressing to regional lymphadenopathy

Back 16

GI anthrax, high mortality rate

Front 17

Two phases of inhalation anthrax

Back 17

flu-like with lymphadenopathy;
followed by edema, sepsis, shock, meningitis, death.

Front 18

spores associated with rice

Back 18

Bacillus cereus

Front 19

toxin associated with fried rice

Back 19

emetic toxin in bacillus cereus (1-6 hr) = PREFORMED

Front 20

strains of bacillus cereus associated with meat or vegetables have what toxin?

Back 20

diarrheal toxin NOT PREFORMED so it causes symptoms 8-10 hrs later

Front 21

morphology of Nocardia

Back 21

non-spore forming gram + rods

Front 22

metabolism of Nocardia

Back 22

strict aerobes

Front 23

Disease states of nocardia

Back 23

Bronchopulmonary disease and Cutaneous lymphocutaneous lesions

Front 24

metabolism of Actinomyces

Back 24

anaerobic

Front 25

Filamentous, anaerobic, non-acid fast, found as normal flora in the female genital tract

Back 25

Actinomyces

Front 26

Granules in actinocymes-infected tissue

Back 26

sulfur granules

Front 27

Disease states in Actinomyces

Back 27

1) suppurative granulomatous lesions
2) cervicofacial (lumpy jaw) actinomyces
3) Pelvic actinomycosis

Front 28

Actinomyces diseases all have this in common

Back 28

abscesses and tissue damage

Front 29

clubshaped gram +

Back 29

Corynebacterium diptheriae (GPR)

Front 30

What does corynebacterium diptheriae grow on?

Back 30

Loeffer's or potassium tellurite media

Front 31

Three species of corynebacterium

Back 31

Gravis, intermedius, mitis

Hint 31

death, intermediate, miotsis

Front 32

lysogenic beta phage acquired exotoxin affects what organs

Back 32

Heart, nerves, kidneys

Front 33

Treatment of corynebacterium diptheriae

Back 33

diptheria antitoxin (DAT), erythromycin, or penicillin