Neisseria Case Study Essay

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The genus Neisseria includes a wide range of species, N. gonorrhoeae and N. meningitidis are the most common when it comes to infections in humans. The other species are sometimes referred to as “non pathogenic Neisseria” yet they still can cause some serious conditions such as endocarditis, meningitis, or pneumonia. In this case study they analyzed a patient with Neisseria sicca endocarditis.
The patient was a 41-year-old-male who had been admitted to a hospital for fever and flu-like symptoms. He was a heavy smoker,, and had a known history of bicuspid aortic valve disease. On his arrival to the hospital, his temperature was 38.5 degrees celsius, heart rate was 98 bpm, and his blood pressure fell in the normal range at 100/80 mmHg. The man’s breathing sounded normal and a systolic murmur was found.
Transesophageal echocardiography showed the man’s bicuspid valve with small vegetation that was attached to the ventricular leaflet. There was also a grade 2 aortic regurgitation and an 8mm aortic ring abscess. They also took blood samples, and decided to start antibiotic therapy. Four of the blood samples had gram-negative cocci growth within a day, so they switched the treatment to ceftriaxone and
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A new transesophageal echography showed the vegetation from earlier had became larger, and there was an extension to the aortic ring abscess. Another 4mm vegetation had formed on the patient's opposite leaflet. A CAT scan showed infarcts in the patient's spleen, liver, and kidneys, and an MRI revealed that Ciprofloxacin was being substituted for gentamicin. Doctors immediately decided to perform surgery. From doing this they found a massively calcified bicuspid aortic valve with endocarditis lesions. Both aortic and mitral valves with vegetation growth were replaced with mechanical prosthetic

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