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81 Cards in this Set

  • Front
  • Back

Not synthesized by the body and must be included in our diet

Essential ions

Ions that are required for normal functioning but in small amounts only

Trace ions

Triggers biological mechanisms in digestive, circulatory, muscular and cerebral systems

Trace ions

Any number of element required by a living organism to ensure normal growth, development and maintenance

Essential ions

Generally not needed in body functions but some may have beneficial action in appropriate dosage

Non-essential ions

Deficiency of Iron2 or Iron3

Anemia

Metabolic function of iron

Constituent of hemoglobin

Metabolic function of iodine

Constituent of thyroxin and triiodothyronine (found in thyroid gland)

Deficiency of iodine

Endemic goiter


Cretinism

Metabolic function of cobalt

Constituent of vit b12 (cyanocobalamin)

Deficiency of cobalt

Deficiency of vit b12 pernicious anemia; an excess-polycythemia

Metabolic function of zinc

Constituent of insulin and carbonic anhydrase

Deficiency of zinc

Anemia, stunted growth, hypogonadism(in males), parakeratosis

Metabolic function of copper

Formation of hemoglobin(increase iron utilisation)



Constituent of oxidase enzymes

Deficiency of copper

Hypochromic anemia


Excessive hepatic storage in Wilson's disease

Metabolic function of sulfur sulfate

Constituent of proteins mucopolysaccharides, heparin, biotin, detoxication

Iron is an essential component of several metalloproteins such as

Hemoglobin


Myoglobin


Many redox enzymes

Present in animals, wherever respiration occurs

Iron

An electron carrier and responsible in the transport of molecular oxygen

Iron

Extra iron is stored in...

Liver


Bone marrow


Spleen

Iron absorption takes places in _______

Duodenum

__________ is given concomitantly for iron absorption

Ascorbic acid

Manifestation of hypochromic microcytic anemia


Listlessness (lacking physical strength and vigor)


Palpitation on exertion


Sore throat and angular stomatitis


Dsyphagia (difficulty in swallowing)


Kilonychia (spoon nails)

Recommended daily allowance of iron for male and female

Male - 8mg/day


Female - 18mg/day

Toxicity of iron

Development of hemochromatosis (resulting from excessive tissue accumulation)

In blood system iron is bound as....

Hemoglobin


Plasma

Mode of linkage of iron in blood system

Heme


Transferrin

Function of iron in blood system

Oxygen and iron transport

Iron in tissues is bound as....

Functional iron (myoglobin, cell heme)


Storage iron

Mode of linkage of iron in tissues

Heme


Ferritin


Hemosiderin

Function of iron in tissues

Cell respiration


Iron pool


Detoxication


Brand names of ferrous fumerate.... And it contains _____% of elemetal iron

Ferrovit


Fergesol



33%


Resistant to oxidation in air

Ferrous fumerate

Has good bioavailability

Ferrous gluconate

Brand name of ferrous gluconate and its content of elemental iron

Fergon


Approximately 12%

Brand names of ferrous sulfate and its content

United home ferrous sulfate


Feosol


Ferglobin


Sorbifer durules



20%

Sterile colloidal soln of ferric hydroxide in complex and with partially hydrolyzed LMV dextran, in water, for injection. Administered by IM only

Iron-dextran injection

Administered IM only, can cause dark urine due to iron sulfate

Iron sorbitex injection

Aka of ferrous sulfate, USP

Iron sulfate


Copperas


Green vitriol


Iron vitriol

Pale, bluish green crystals which are odorless

Ferrous sulfate, usp

Effloresces in dry air and oxidizes mosit air to form brownish yellow basic ________.

Ferrous sulfate


Ferric sulfate

Prep of ferrous sulfate

As a by product of "pickling" of steel


Obtained from treated mineral pyrite (fool's gold or iron pyrite)

Use of ferrous sulfate


Used as hematinic


Irritating to GI mucosa due to astringent action of soluble ion

Ferrous sulfate, USP

Therapeutic use of iodine

Fibrinolytic agent in syphilis and leprosy


Expectorant


Ameliorating agent in hyperthyroidism

Daily dose of iodine in male and female


Male - 140mcg/day


Female - 100mcg/day

Source of iodine

Salt water fish


Shellfish


Iodized salt and milk

Treats infections in wounds

Povidone iodine

An expectorant to liquefy thick and tenacious sputum in several lung condition

Potassium iodide

Prep of iodine

Iodine soln and tincture


Povidone iodine


Potassium iodide

Has central role in immune system

Zinc

Recommended daily allowance of zinc in male and female

Male - 11mg/day


Female - 8mg/day

Toxicity of zinc

Metal fume fever


Characterized by dehydration, electrolytic imbalance, stomach pain, dizziness


High zinc intake are known to lower copper absorption

Recommended daily allowance of copper

900mcg/day

Toxicity of copper

Wilson's disease (hepatolenticular degeneration)


Leads to excess accumulation of copper in brain, liver and kidney



DOC: penicillamine

Used as anticargiogenic

Fluoride

Toxicity of fluoride

Fluorosis

Deficiency of fluoride

Tooth decay

Causes CNS depression in small doses (____-____)

Bromide (.2 to 2g)

Bromide in large doses (___-____) depresses all reflexes and used as a medication for _______

4-8g


Epileptic seizures

Toxicity of bromide that is characterized by insomia, restlessness, dizziness, weakness

Bromism

Uses of arsenic

Rat poison component


Protoplasmic poison for trypanosomiasis and amoebiasis


Used in leukemia

Toxicity of arsenic

Headache, confusion, sever diarrhea, drowsiness



Mees' lines (development of leukonychia(white spots) in fingernails

Uses of lithium

Mood stabilizer in manic-depressive psychosis


Depressant to the CNS and to circulation


Has diuretic effect

Toxicity of lithium

Affects the kidneys and induces diabetes insipidus

Uses of gold

Cure for rheumatoid arthritis and non-disseminated lupus erythematosus


Uses of Aluminum

Used as astringent (soluble salt like alum, chlorine and sulfate)



Used as gastric antacids (insoluble salt like phosphate and hydroxides)



Deodorant

Toxicity of silver

Argyria

Used as styptic and protein precipitant

Silver

Can be an antiseptic, astringent, irritant-corrosive ( as the concentration of free silver increases)

Silver

Uses of mercury

Diuretic


Germicide


Antiseptic

Toxicity of mercury

Hydrargyria

Compounds of mercury

Mercurous chloride


Ammoniated mercury


Yellow mercuric oxide

Compound of silver

Toughened silver nitrate

Compounds of gold

Gold sodium thiomalate


Aurothioglucose

Compound of lithium

Lithium carbonate

Compounds of arsenic

Potassium arsenite (fowler's soln) - soln of As2O3 and KHCO3

Compounds of bromide

NaBr


KBr


NH4Br

Compound of fluoride

Sodium fluoride

Uses of strontium

Sedative (in form of Strontium bromide)


Treatment of osteoporosis (strontium lactate)


Dentrifice

Compounds of strontium

Strontium chloride (desensitizing agent)


Strontium ranelate