Acids Inorg Chem Finals

Front 1

Conversion of drugs to chemical forms convenient to their product formulation

Back 1

Acids and bases

Front 2

Buffers

Back 2

Maintains pH with prescribed limits

Front 3

Prevents oxidative decomposition

Back 3

Antioxidants

Front 4

Primary solvent in most pharm prep

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Waters

Front 5

Storage and dispensing container of most drug products

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Glass

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Proton donor

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Acid

Front 7

Proton acceptor

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Base

Front 8

Acids and bases are....

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Conjugate pairs

Front 9

Neutralisation is a rxn between _____ and ______ to form _______ and _______

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•Acid and hydroxide

•Salt and water

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Acid or base that produce ions in aqueous soln to conduct electricity

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Electrolytes

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ionizes large extent (70-100%) into ions in aqueous soln

Back 11

Strong electrolytes

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ionizes to small extent into ions in aqueous soln

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Weak electrolytes

Front 13

Synonyms of boric acid

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★Boraric acid

★Hydrogen borate

★Orthoboric acid

★H3BO3

Front 14

Boric acid often found in...

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· sea waters

· certain plants

· nearly all fruits

· some volcanic steam jets

Front 15

Native boric acid

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Sassolite

Front 16

Boric acid is ______ in air.

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Stable

Front 17

Boric acid is soluble in ______ and ______.

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Water and Alcohol

Front 18

Boric acid is freely soluble in _______, _______ and ______.

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✓glycerin

✓boiling water

✓boiling alcohol

Front 19

Adding ______ decreases _______ of boric acid

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— HCL

— solubility

Front 20

boric acid is not absorbed through intact skin but is ______ when ingested.

Back 20

Highly toxic

Front 21

Boric acid a are used as....

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~ solutions

~ ointments

~ dusting powder

~ as antiseptic

Front 22

Boric acid is a weak _______ agent.

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Bacteriostatic

Front 23

Boric is used as an eyewash at ______ concentration

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2.5-4.5%

( More conc soln should be diluted with water before use)

Front 24

Boric acids are buffers for opthalmic soln at what preparation?

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1.9% boric acid with pH level of 5

Front 25

Boric acid a are used in preparation of _______ and _______.

Back 25

- Aluminium acetate USP XVII

- Aluminium subacetate soln XVII

(Should not be used alone when used as a buffer because it is not enough)

Front 26

Boric acid is also used as buffer for ___________ to maintain _________.

Back 26

Topical medication

acidic pH

Front 27

Synonym of Hydrochloric acid

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1. Muriatic acid

2. Spirit of sea salt

3. Marine acid

4. Chlorhydric acid

Front 28

HCI is an aqueous soln of HCl gas containing ________ and _________ by weight of hcl

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NLT 35% & NMT 38%

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Properties of HCI

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Colourless fuming liquid, pungent odor

Front 30

Non fuming liquid soln of HCl is prepared by _________ with ________

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Diluting hcl

2 volumes of water

Front 31

More ionized than most acids and attacks many metals with evolution of H gas.

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Hydrochloric acid

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From Latin word "brine"

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Muriatic acid

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Muriatic acid contains ______ and a number of impurities including ______,________,________and_________

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30% hcl

Chlorine, arsenous, sulfurous acid and iron

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Acidifying agent

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HCI

Front 35

Disadvantage of HCl

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Hygroscopic

Front 36

Salt of organic amine are________.

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Solid form (easy to incorporate into solid dosage forms)

Front 37

Most drugs are available as _______.

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HCl salts

Front 38

___________ is a solution of HCl gas containing _______ and _______ of HCl in each _______ of soln

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*Diluted hydrochloric acid

*NLT 9.5g and 10.5g

*100ml

Front 39

It exists normally in _______. Aiding the conversion of pepsinogen to _______ and used as _______.

Back 39

gastric juice (.2% hcl)

pepsin and gastric antiseptic

Front 40

Used in treatment of achlohydria

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Diluted hcl

Front 41

Deficiency of HCl acid

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Hypochlor-hydria

Front 42

Diluted hcl is given in doses at ______. It must be highly diluted with _______ and should be administered through a ______.

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1-10cc

Water

Straw

Front 43

Glutamic acid hcl and betaine hcl are in_______.

Back 43

Capsule form

Front 44

Synonym of nitric acid

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Spirit of Nitre

Aqua Fortis

Aqua fuerte

HNO3

Front 45

Nitric acid is an aqueous soln containing ________ by weight of HNO3.

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NLT 69%-71%

Front 46

Nitric acid is __________ fuming liquid that has_________.

Back 46

Highly corrosive

Highly irritating odor

Front 47

HNO produces ________ in animal tissues due to __________ present.

This rxn is called _________.

Back 47

yellow stain

aromatic amino acids

Xanthoproteic test

Front 48

HNO is a strong ________, _______ and _________ agent.

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Monotropic acid

Oxidizing agent

Nitrating agent

Front 49

Oxidizing property of HNO is enhanced by ________ which is a product of _______ of HNO3

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Presence of HNO2

Photochemical decomposition

Front 50

Boric acid + glycerin

Back 50

Boroglycerin glycerite

Front 51

Boroglycerin glycerite is used as an....

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Suppository base

Front 52

When hcl is oxidized it will result to....

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Chlorine gas