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13 Cards in this Set
- Front
- Back
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Inflammation |
A protective response intended to eliminate the initial cause of cell injury aswell as the necrotic cells and tissues resulting from the original insult. (31) |
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Acute inflammation |
A rapid response to injury or microbes and other foreign substance that isdesigned to deliver leukocytes and plasma proteins to sites of injury. (33) |
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Serous inflammation |
An outpouring of a watery, relatively protein-poor fluid that, depending on thesite of injury, derives either from the serum or from the secretions of mesothelialcells lining the peritoneal, pleural, and pericardial cavities. (43) |
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Effusion |
Fluid in a serous cavity (43) |
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Fibrinous inflammation |
Inflammation occurring as a consequence of more severe injuries, resultingin greater vascular permeability that allows large molecules (such as fibrinogen)to pass the endothelial barrier. (43-44) |
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Abscess |
Focal collections of pus that may be caused by seeding of pyogenicorganisms into a tissue or by secondary infections of necrotic foci. (44) |
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Ulcer |
A local defect or excavation of the surface of an organ or tissue that isproduced by necrosis of cells and sloughing of inflammatory necrotic tissue. (44) |
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Cytokines |
Polypeptide products of many cell types that function as mediators ofinflammation and immune responses. (48) |
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Chronic inflammation |
Prolonged inflammation in which active inflammation, tissue injury, andhealing proceed simultaneously. (53) |
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Granulomatous inflammation |
A distinctive pattern of chronic inflammation characterized by aggregates ofactivated macrophages that assume an epithelioid appearance. (56) |
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Stages of leukocyte extravasation |
1. In the lumen: margination, rolling, adhesion to endothelium 2. migration across the endothelium and vessel wall 3. Migration in the tissues toward a chemotactic stimulus |
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3 major components of acute inflammation |
1. increase blood flow 2. permit plasma proteins and leukocytes to leave circulation 3. emigration of leukocytes and accumulate at injury focus |
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5 signs associated with inflammation |
redness swelling heat pain loss of function |
