What Is NF Pathophysiology?

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NF pathophysiology is initiated by trivial injury but rapidly progressive necrotising infection of the superficial fascia ensues.The primary site of infection is superficial fascia, than the infection rapidly spread through the fascial planes (horizontal spread) without involving the skin, horizontal spread starts with initial trivial injury, the bacteria get lodged into the superficial fascia, proliferate and produces hyaluronidase enzyme.This enzyme causes degradation and necrosis of the fascial layers; creates more favourable atmosphere for bacterial growth and produces rapid, uncontrolled spread of infection. This is the reason that patients become sicker without significant local

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