Using T Pa For The Management Of Acute Ischemic Stroke Essay

1774 Words Nov 21st, 2016 8 Pages
Brown, Burton, Nazarian, and Promes (2015) along with the Agency for Healthcare Research and Quality (AHRQ) provides guidelines that support the use of t-PA for the management of acute ischemic stroke. The guidelines are based on their own reviews of evidence based studies to collect information to generate the guidelines. The objective of this study was to answer the question is t-PA safe and effective for patients with ischemic stroke if given within 3 hours of onset and also if given between 3-4.5 hours from onset. The methods used to collect the evidence were through hand-searches of published literature and searches of electronic databases. 195 articles were identified as relevant to review and analyze. Expert consensus was used to formulate the recommended guidelines. The results are evidenced by the recommended guidelines as follows. T-PA administration within 3 hours of onset should be offered and may be given to select patients with acute ischemic stroke at institutions where systems are in place to safely administer the medication. The increased risk of symptomatic intracerebral hemorrhage (sICH) should be considered when deciding whether to administer t-PA to patients. In addition t-PA may be offered and given to patients with acute ischemic stroke within 3-4.5 hours after symptom onset, despite the known risk of sICH and the varying degree of benefit in functional outcomes. These are designated as Level B recommendations which are for patient care that…

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