Salbutamol Assignment

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Pharmacology 1 Major Assignment

The chemical name of salbutamol is 1-(4-hydroxy-3-hydroxymethylphenyl)-2-(t-butylamino)-ethanol sulphate, chemical structure is (C13H21NO3)2 • H2SO4 and molecular weight is 576.7g/mol
Generic Name: albuterol
Commonly used brand name(s):

Available doses and dosage forms:

Oral salbutamol:
Adults and Children over 12 years:
Usual starting dosage of salbutamol is 2mg or 4 mg 3 or 4 times a day. A dosage exceeding 4 milligrams of salbutamol 4 times per day should be used only when the patient is not responding well. If the desirable response is not achieved with 4 milligrams, it should be carefully increased up to a maximum of 8 milligrams 4 times daily as tolerated.
Children 6-12 years:
The Usual starting dose of salbutamol is 2 milligrams 3 or 4 times a day, If the desirable response is not achieved using 2 mg salbutamol, the dose should be increased up to a maximum of 24 milligrams per day divided into 3 or 4 doses.
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Salbutamol metered dose inhaler (MDI):
The dose of salbutamol inhaler for adults, and children over four years old:
► For the treatment of acute bronchial asthma or bronchospasm, the usual dose is one puff (100 mcg) or two puffs (200 mcg) of salbutamol inhaler every 4 to 6 hours.
► For maintenance therapy of bronchial asthma, one or two puffs 3 to 4 times daily.
► For the prevention of bronchospasm caused by exercise, take two puffs 15 minutes before the exercise.
Salbutamol dry powder inhaler (DPI) capsule:
Salbutamol DPI is taken only by oral inhalation, using an inhalation

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