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SDD: A Continuous Gingivitis Case Study

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continuous dosing. The 20-mg twice per day dose exerts its therapeutic effect by enzyme, cytokine, and osteoclast inhibition, rather than by any antibiotic effect. The use of systemic host modulatory therapy may not only improve the patient’s periodontal condition but also provide systemic benefits for other inflammatory disorders with related tissue destruction, such as arthritis, cardiovascular disease, dermatologic conditions, diabetes and osteoporosis. SDD is indicated in the management of chronic periodontitis66. SDD should not be used in conditions such as gingivitis or periodontal abscess, or whenever an antibiotic is indicated. SDD can be used in aggressive periodontitis cases that are being treated nonsurgically67. SDD may also be

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