Organ Transplantation Paper

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Transplantation is the surgical removal of an organ from a donor and transferring it into the recipient whose organ has failed. However, solid organ transplant rejection by the recipient's immune system may occur. Transfusion before transplantation was found to reduce solid organ transplant rejection by inducing regulatory T-cells and immunomodulation with down-regulation of the immune system. Similarly, ABO blood group matching, tissue typing, cross matching and using immune suppressants are among the methods used to avoid rejection. Interestingly, clinical observation in humans noted significant correlation between the rate of bone marrow rejection and the number of antecedent transfusion. This is because the bone marrow transplant is matched …show more content…
Similarly, organ transplantation may involve the removal of some part of the body and relocating it to the diseased position within the same patient (Pearson, Madsen, and Webber, 2014). According to the United Network for Organ Sharing (UNOS), there are seven types of organ transplant which are now performed in the United States. These include heart, kidneys, lungs, pancreas, liver, intestines plus the vascularized composite allografts (VCAs) which are now available for hand and face transplantation. Kidney transplants are the most commonly performed type of transplant surgery whereas the intestine is the least common type. However, double transplants such as heart/lung or pancreas/kidney are carried out in some cases. In addition, transplantation is currently progressing and better improved methods are used to achieve successful outcomes. These improvements include HLA and cross matching for transplant compatibility and good preservative methods are used during organ or tissue preservation (Al-Khafaji, 2013). Therefore these developments have led the increase of the survival-time for the recipient transplant. Recently, press release has named the first person who became the longest surviving heart-lung transplant recipient in the world. This patient from Herefeild Hospital is active and working in retail after thirty years of his

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