Organ Transplants Research

Improved Essays
Are Animals the Future of Human Organ Transplants?
Can animals be the future of organ transplants? Thought the research concluded many pros and cons of this. Pros : Decreasing the number of people needing transplants, using the ability of the monkey to see how the organ may react in us. Cons : Harming the animals, Animals becoming too much alike to humans, receiving diseases the animals may carry. Although humans need organs are the animals the way to go? If animals can actually be used for the future of organ transplants in humans,many lives would be saved for the people in need of the organ or organs.
About 2 dozen Americans die each day in need of a transplant. (Fikes) In 2014 there was 317 million people living in United States of America
…show more content…
“Worries over animals whose brains contain some human cells and what might happen if the cheras were able - and allowed - to reproduce.” (Bernstein) “pigs and other animals may contain viruses and other pathogens that could be transferred to transplant patients” (Bradley). “The complexities of the immune system and the possibility of infection by pig viruses are formidable..”( Reardon 152). Many regulators are uneasy about the safety and the risk of ig organs transmitting diseases to immunosuppressed human (Reardon 153). “Patients died within a few months, usually because the immune system attacked and rejected the organ” (Reardon). “Even if pigs could be kept entirely sterile, the ig genome is sprinkled with dozens of dormant porcine endogenous retroviruses (PERVs) and studies conflicted as to whether these could become active in humans “ (Reardon 153). PERV problem is a major safety concern. The virus replicates poorly in human tissues and the risk of spreading it is virtually non-existent.” (Reardon 154) “Most major epidemics started with an animal pathogen then jumps to humans.“ (Reardon 154). As a consequence many people can be harmed in the medical discovery of using animals for …show more content…
Human stem cells are put into animal embryos.(Fikes). These are called chimeras. A chimera is a single organism composed of cells of different zygotes. This can result in male or female ergano. “One route that Izpis uses is to put the region-specific pulpotomy stem cells into an animal embryos very early in that embryos development process. This strategy carries the risk of pluripotent cells migrating elsewhere..” (Fikes). Another route would be to coverent the pluripotent stem cells into a more mature ‘progenitor’ cells that have partly differentiated. These progenitor cells can only become one one organ.” (Fikes). According to Thompson “when precursor tissue from 16-day-old rabbit embryos is implemented in an adult rabbits, it develops into an adult kidney, connecting itself to the host of the blood supply.” “The adult rabbits did not reject the foreign kidneys because the embryonic tissues was transplanted before it had producing the protein that would alert a host’s immune system to foreign cells” (Thomson) . One of the first stages of the method that American Scientist use involves genetically knocking out an organ in the animal embryo. “The scientist then injected human stem cells, which they hope will replace the missing organ before putting the embryo in the womb of a female pig or sheep.” (Oliver). In the meantime many people are still dying awaiting a

Related Documents

  • Improved Essays

    Organ Donation Case Study

    • 1150 Words
    • 5 Pages

    The shortage of organs available for transplants and the increase of kidney failure has created an epidemic of patients on dialysis who await a donor. As the current program of unpaid voluntary donors in North America is not adequate, many urge that compensation for organ donation could be a legitimate solution. The demand for a realistic resolution in organ transactions raises concerns on the breach of human integrity. This paper will explore the ethical dilemma of selling organs as commodities as morally acceptable and the possible justification by the benefits received for both the donor and recipient.…

    • 1150 Words
    • 5 Pages
    Improved Essays
  • Great Essays

    In 1981, “Martin Evans of Cardiff University, UK, then at the University of Cambridge, is [was] first to identify embryonic stem cells - in mice” (“Stem Cell Timeline: The history of a medical sensation”). The cloning of Dolly, a Finn Dorset sheep, proved that cloning of mammals was possible when using a procedure known as somatic cell nuclear transfer (SCNT). Less than a decade later, a great breakthrough occurred when James Thomson with a group of scientists found the exact mixture and the right technique to withdraw stem cells from an embryo while keeping them viable. “By using the SNCT procedure to produce human embryos genetically matched to patients and using the techniques developed by Thomson to grow human embryonic stem cells, scientists hope one day to be able to replace or regenerate failing human cells and tissues without complication of tissue rejection” (Langwith 17). Thomson’s work laid a foundation for stem cell therapy, where healthy cells will replace diseased or dysfunctional cells. These cells will attack the root of the illness rather prescribing the current treatment method, which tends to the symptoms. The cells in this area of study are able to live independently under controlled conditions or they can reproduce in the special solutions of petri dishes and test tubes. In these manipulated…

    • 1762 Words
    • 8 Pages
    Great Essays
  • Decent Essays

    In the article of Animal Farming: Growing Human Organs, Andrew Hitchings discuss the issues of organ shortages in the United States. Hundreds of citizens become an addition to the waiting list for organs every day, however even if received one, the complications do not stop there. One contradicting issue that surfaces is the genetic relationship between one’s immune system and organ. One particular method that can resolve this issue of preventing the immune system’s rejection of organs is the growth of new organs from the cells of a patient. With these scientists are capable of transforming human cells into induced pluripotent stem cells; which could possibly evolve into any cell sort. However, one challenging factor demonstrates that the growth…

    • 179 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    The need for organ transplants are high in demand, but the aren’t many if any people who are willing to donate their organs for medical reasons. There are waitlists for people in need for transplants but many die before hearing any good news. People and families are put in a tough position when making this decision. Its there a way to make it easier to have and organ supply? If so what are the options that one has that is still willing to honor their wishes?…

    • 1228 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    However, I believe the scientific community should focus all of their efforts into induced pluripotent stem cells, because the long-term advantages outweigh the disadvantages of human embryotic and adult stem cells. The use of human embryotic stem cells is immoral; because embryos have to be created through in vitro and then are donated to science after removing the stem cells. In order to advance our understanding of stem cells, we should focus in a process that does not take a life. Adult stem cells are useful, but since they come from specialized regions they cannot specialize into any type of cell. In other words, adult stem cells are limited as far as the type of cells they could turn into. On the other hand, induced pluripotent stem cells take the advantages of both human embryotic and adult stem cells. Induced pluripotent stem cells do not require an embryo and can specialize into any type of cell. If the scientific community and the government were able to join efforts in supporting the research of induced pluripotent stem cells then a safer way of introducing iPSCs could be found. These stem cells could help create transplantable tissues and organs, without sacrificing embryos or having them rejected by the patients’…

    • 775 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    This means that the embryo has not yet affixed itself to the uterine wall. In the first four or so days of embryonic cell division, embryonic stem cells are considered totipotent. This means that it has the ability to turn into any cell and can give rise to a whole organism. After the first four days, embryonic stem cells become pluripotent, which means they can specialize into any sort of tissue cell but cannot give rise to a whole organism. Researchers typically use pluripotent embryonic stem cells. Due to the near limitless differentiation that embryonic stem cells are capable of, scientists, researchers, and medical professionals are studying the potential for cell-based regenerative therapies, tissue transplants, and the replacement of aged or diseased cells. However, there is an ethical dilemma. In the process of extracting embryonic stem cells from the blastocyst (source of embryonic stem cells) the embryo is subsequently destroyed. Those opposed to the cultivation of embryonic stem cells believe that destroying an embryo, even though it may be in vitro (ie: not in a womb), is tantamount to…

    • 926 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    As the lead surgeon in a major hospital, and by virtue of seniority and the key decision maker for organ transplant cases, involving Jerry, 55-year-old male, a family man and mid-level manager, Lisa 12-year-old female with lifelong health issues, Ozzy, 38-year-old male who happened to be a homeless drug abuser, and finally Dr.Doe, 35-year-old male an oncologist and also Lisa’s dad. Who are all waiting and hoping for suitable heart to become available and a quick sound decision to be made pertaining which of these patients will receive the heart and schedule surgery same day.…

    • 723 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    There are many challenges to successful organ transplants, including matching a recipient and a donor based on matching genetic variability. It is extremely difficult to match MHC perfectly with a donor and a recipient as there are many locations where genetic differences can still cause a rejection reaction by the recipient. A familial donor is usually the closest to a perfect genetic MHC match that a recipient can find. The closer the match of genetic variability, the better the chances that the graft or transplant will be a success.…

    • 629 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    The process of completing a transplant of human organs from one individual to another is very complex on every level. There are many touch points or intersections where critical data, such as blood type, can be verified. Any piece of information that is not an exact match should give pause to the process until there is no doubt that all of the checks are in place to secure a viable organ and recipient are matched and successfully transplanted. Healthcare entities that practice similar specialties can learn from one another and sometimes the best processes come out of tragedy. As a leader in a healthcare organization I would learn from the mistakes of others. Following the Jesica Santillon transplant mismatch Duke Medical Center underwent extensive surveys and audits related to their…

    • 471 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Embryonic Stem Cell

    • 882 Words
    • 4 Pages

    Human Embryonic Stem Cells or (hESCs) are taken from human embryos, however these embryos are not normal ones. The (hESC) are embryos that were fertilized in a process known as in vitro fertilization. In vitro fertilization is usually done in a clinic of some sort and are then given to researchers for research with permission from the people who have donated. The human embryonic stem cells are not created from a woman, they are created inside of a lab. The process of creating hESC’s is called Cell Culture. The process starts with taking an embryo from the preimplantation stage and then continue to place it into a culture dish with a kind of broth known as a culture medium. The cells then disperse all around the culture dish. When the cells divide and multiply they do not always survive. When enough cells survive inside of the culture dish, they are taken out and inserted inside brand new culture dishes. The process known as sub culturing is repeated for a few weeks, even months before the process is repeated. When sub culturing takes place, each cycle is known as a passage. The process of Sub culturing creates millions of embryonic (hESCs) , this is also known as a stem cell…

    • 882 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Pigs and primates are currently being considered as a source of organs for xenotransplantation. The pig is a model organism for this type of transplant because it has decreased time needed to reproduce and mature, and has organs very similar in size to humans. There are multiple barriers, however, that xenotransplantation must overcome in order to be successful. The most obvious problem arises because host and donor are different species, and therefore contain very different antigens in their bodies. This means that there is simply more for the immune system to identify as foreign and destroy, increasing the risk of organ transplant rejection. Another barrier to xenotransplantation includes the possibility of diseases bypassing the species barrier and infecting humans.…

    • 983 Words
    • 4 Pages
    Improved Essays
  • Superior Essays

    Human Organ Transfer

    • 1523 Words
    • 7 Pages

    Often called into question is the validity of the argument that human cells and tissues are the property of the hosts they came from after being removed from their body. To label parts of the human body, our anchor to this world, as personal property is very difficult. Even more difficult is deciding to whom these cells belong to after they are no longer a part of the person they came from. It is important to look at the benefits of research on the cells of people in order to help others. However is it not equally as important to analyze the inhumane nature required to take the cells of another human being to research and profit without the patient's informed consent? Deeming who cells belong to is not a conversation that can be had without…

    • 1523 Words
    • 7 Pages
    Superior Essays
  • Decent Essays

    Donor tissue should be removed within 12-24 hours of death. The optimal death-to-preservation time is 12-18 hours. There is an attempt to age-match donors and recipients. Corneas from infants (3 years and under) are used only very occasionally, even for pediatric transplants, as they are associated with surgical, refractive and rejection problems. Most surgeons do not use corneas from donors younger than 24 months, as these corneas are extremely flaccid and can result in high corneal astigmatism and myopia postoperatively. Most eye banks establish a lower donor age limit of 24 months and an upper age limit of 70 years, as older corneas tend to have lower endothelial cell counts…

    • 179 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    Even research institutes that just want to test the theory of xenotransplantation although say they take care of the pigs and that they’re well looked after at the end of the day the pigs will be going through a number of different trials and be subjected to many injections and chemicals along with surgical procedures that cannot be good for the pig. And aside from this these pigs will essentially be bought up to have their organs harvested for humans. This is a major ethical issue on its own as do humans as just another species on earth have the right to treat animals this way and modify them as they please for the sole reason of using them to save other humans. However this is also not as issue as In a way we breed pigs and farm them for their meat and to eat them so to use them for organ harvesting vs eating them is really the same thing as in both cases the pig down die. And for years humans have been okay with eating…

    • 1573 Words
    • 7 Pages
    Improved Essays
  • Great Essays

    Stem Cell Importance

    • 1517 Words
    • 7 Pages

    Stem cell research on adult and embryonic stem cells has the potential to develop cures for diseases that kill millions of people all over the world. First off, stem cells are the unspecialized cells from which differentiated cells develop(Miller et Levine). In the early 1900’s, attempts were made to fertilize mammalian eggs outside of the human body. It was then discovered that some cells were able to generate blood cells. In 1968, the very first bone marrow transplant was done successfully on two siblings with severe combined immunodeficiency(Murnaghan). In the next thirty years, scientists uncovered more facts about adult and embryonic stem cells. In 1999 and 2000, scientists “discovered that manipulating…

    • 1517 Words
    • 7 Pages
    Great Essays