Myogenic Response

Myogenic response is the intrinsic property of vascular smooth muscle to respond to changes in intravascular pressure. The innate myogenic activity is crucial for autoregulation of blood flow normal hemodynamic function and maintaining vascular resistance. The myogenic activity arises from arteries and arterioles denuded of endothelium and autonomic nerve control. Nonetheless, endothelium produces several vasoactive mediators, including nitric oxide, prostacyclin, and endothelium-derived hyperpolarizing factor that play critical roles in vascular tone and cerebral autoregulation.
The autonomic mechanism
The cerebrovascular bed is well innervated by both sympathetic and parasympathetic nerve fibers. However, the role of the autonomic nerve