Blood pressure , as a physiological variable of humans, is a hydrostatic pressure, utilized by blood on the walls of blood vessels.(Tortora and Derrickson 2011). It is caused by the contraction of the ventricles and the amount of blood in the whole cardiovascular system. The mean blood pressure (the average pressure in the cardiac cycle) is coordinated in order to provide adequate blood transfer to the tissues.(Saladin,2001). The decrease of blood pressure is followed by an increase of heart rate.The normal blood pressure is 120 mm HG systolic and 80 mm HG diastolic blood pressure
There are three main types of blood pressure regulation considering homeostasis: Neural regulation …show more content…
Angiotensin II, as a strong vasoconstrictor, increases blood pressure by stimulating the systemic vascular resistance and the raise of the blood volume, therefore the blood pressure too.Angiotensin II also stimulates the production of aldestorne by the adrenal cortex.Aldosterone provoke kidneys to reabsorp more sodium ions and water. Due to the sympathetic stimulation,the adrenal medulla secretes epinephrine and norepinephrine,which raise the heart rate and respectively,the cardiac …show more content…
Chemical,decreasing blood pressure ,which are released tissue cells with an active methabolism are K+,lactic acid(lactate),adenosine.Endothelial cells release nitric oxide
In the modern medicine pharmacology,there are five main types of medicine,regulating the chormones activity,therefore regulating blood pressure:Angiotensin-coverting enzyme inhibitors(ACE inhibitors ,calcium-channel blockers,angiotensin receptor blockers ,diuretics and beta-blockers
Angiotensin-coverting enzyme inhibitors(ACE inhibitors)
ACE inhibitors block the angiotensin-covering enzyme which leads to unwinding of blood vessels and dercreasing the quantity of re-absorped water in the kidneys
Calcium-channel blockers Calcium-channel blockers lower the volume of calcium , going to the smooth muscle cells.Muscle cells relax and blood pressure