Marchiafava-Bignami Disease Research Paper

Decent Essays
Marchiafava- Bignami disease is an illness typified by extreme demyelination of the corpus callosum, and is most often seen in patients exhibiting extreme alcoholism or nutritional insufficiency, although it has been seen in patients who do not consume alcohol[1]. Some clinical hallmarks of MBD are tetraparesis, astastia –absasia, impaired consciousness and neuropsychiatric disorders [2]. In previous eras, MBD was diagnosed post-mortem during autopsy, however with the dawn of computed tomography (CT) and magnetic resonance imaging (MRI) early diagnosis is now possible [2] . Some early symptoms of MBD include dementia, paranoia, lethargy, tremors, abnormalities in gait, ataxia and seizures. If diagnosed early enough, patients may recover with

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