Antibiotic sensitivity
Introduction: Initially, when treating patients for bacterial infections it is important to understand the type of microorganism being dealt with and what type of antibiotic will kill it. There are three main characteristics that scientists look for in useful antibiotics: the toxicity, manufacturing, and its ability to work and be expelled safely. First, is the ability of the antibiotic reaching its target with minimal toxicity to the patient. The second characteristic is if this antibiotic can be manufactured in vitro and then transferred to in vivo successfully. The final characteristic is the ability of the antibiotic to stay in the system long enough for the treatment to be effective, but also able to be expelled from the body when finished. …show more content…
These include species such as Penicillium notatum and Penicillium cephalosporium. These are effective against gram-positive bacteria by inhibiting peptidoglycan synthesis (Todar,2012). There are a few types of Streptomyces including clavuligerus, cattleya, and griseus. These all work against both gram-positive and gram-negative bacteria. Another type of organism responsible for creating antimicrobial agents is Bacillus subtilis which inhibits wall synthesis and Bacillus polymyxa that disrupts the cell membrane (Harvey,1998). Since there are so many different microorganisms that create antimicrobial agents there will continue to be new species discovered for a long time. Lastly, there are some conditions that will affect the outcome when testing for the sensitivity of microorganisms using antimicrobial agents. One of the biggest is the range of pH, which should be between 7.2-7.4 and have a thickness of 4mm. Another is the turbidity and the amount of organism placed onto the agar plate. All of these can have an adverse effect on the
Introduction: Initially, when treating patients for bacterial infections it is important to understand the type of microorganism being dealt with and what type of antibiotic will kill it. There are three main characteristics that scientists look for in useful antibiotics: the toxicity, manufacturing, and its ability to work and be expelled safely. First, is the ability of the antibiotic reaching its target with minimal toxicity to the patient. The second characteristic is if this antibiotic can be manufactured in vitro and then transferred to in vivo successfully. The final characteristic is the ability of the antibiotic to stay in the system long enough for the treatment to be effective, but also able to be expelled from the body when finished. …show more content…
These include species such as Penicillium notatum and Penicillium cephalosporium. These are effective against gram-positive bacteria by inhibiting peptidoglycan synthesis (Todar,2012). There are a few types of Streptomyces including clavuligerus, cattleya, and griseus. These all work against both gram-positive and gram-negative bacteria. Another type of organism responsible for creating antimicrobial agents is Bacillus subtilis which inhibits wall synthesis and Bacillus polymyxa that disrupts the cell membrane (Harvey,1998). Since there are so many different microorganisms that create antimicrobial agents there will continue to be new species discovered for a long time. Lastly, there are some conditions that will affect the outcome when testing for the sensitivity of microorganisms using antimicrobial agents. One of the biggest is the range of pH, which should be between 7.2-7.4 and have a thickness of 4mm. Another is the turbidity and the amount of organism placed onto the agar plate. All of these can have an adverse effect on the