Effect Of Antidepressants On Patients With Mild And Moderate Depression

1657 Words Nov 28th, 2016 7 Pages
Depression is a big worldwide problem, and in USA antidepressants are the third most common prescribed drug. It is a problem that appears to be on the rise. However, a lot about the function of antidepressants and why they seem to be working better in some individuals still remains unknown.
Some data actually suggests that antidepressants works as good as taking a sugar pill. A meta-analysis (2010) were six separate studies were analysed to compare the effectiveness of antidepressants indicated that patients with mild and moderate depression might be treated better with alternatives to antidepressants. Which, according to the researches, does not help much more than an inactive placebo. The two drugs analysed were paroxetine and imipramine. Paraxetine is a selective serotonin reuptake inhibitor while imipramine is a tricyclic antidepressant drug. While a placebo usually is described as inactive and nonspecific compared to so called real antidepressant drugs.
There is an effect called the placebo effect which is an efficient tool in treating depression. This is when people think that they are helped regardless of the fact that they are taking an inactive sugar pill. However, research has shown that there are some changes happening in the brain leading to the release of molecules associated with the placebo effect (VILKA CHANGES??).
Data have shown that the placebo effects have a 30-45% Klerman and Cole 1965; Stark and Hardison 1985; Brown et al. 1988. 14 response compared…

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