Essay about Causes And Treatment Of Serratia Marcescens

1154 Words Sep 5th, 2016 null Page
In everyday life, people use disinfectants, substances used to destroy viruses and microbes such as bacteria and fungi1, to clean their bathrooms. If not properly sterilized and cleaned, the bathroom can be a domain for numerous bacteria including ubiquitous Serratia Marcescens, a short, rod shaped, facultative anaerobic, opportunistic pathogen that can cause nosocomial infections such as urinary tract infections, bacteraemia, meningitis, sepsis and cerebral abscesses2. Facultative anaerobic meaning that it can live and grow with or without molecular oxygen3. Serratia Marcescens is a gram negative bacterium. Gram negative bacteria have a thin cell of a single layer of peptidoglycan that is enclosed by an outer membrane. The outer membrane is surrounded by special phospholipids composed of fatty acids called lipopolysaccharides that are attached to a glucosamine phosphate dimer. One glucosamine is then attached to a core polysaccharide that extends to the O polysaccharides (refer to appendix 1)2,4. The outer membrane also serves as means to regulate the uptake of nutrients and the exclusion of toxins. The highly charged nature of lipopolysaccharides confers an overall negative charge to the gram-negative cell wall4,5. Due to its preference for damp conditions, Serratia Marcescens is commonly found growing in the bathroom (especially on tile grout, shower corners, toilet water line, and basins), where it produces its red pigmentation called prodigiosin while it feeds off…

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