C. Elegans

In 1963, the South African biologist Sydney Brenner proposed C. elegans as a model system for studies of development and neurobiology. Researchers share their findings in C. elegans genome via the internet with other researchers from around the world. The process of sharing the genome database on the world wide web provides a working framework for researchers who are working on the human genome project In 1969, John Sulston developed a technique to freeze and thaw the worm. As a result, the numbers and availability of both wild type and mutated worms have increased . Moreover, many tools have been invented to speed up research using C. elegans. Advanced microscopes, various antibodies, different kinds of reporter genes for labeling and the use of laser microbeams to ablate individual cells are examples of such tools.
Caenorhabditis elegans, is a free-living, non-parasitic soil nematode that can be safely uded in the laboratory and is common around the world.What is unique to this organism is that wild-type individuals contain a constant 959 cells. The position of cells is constant as is the …show more content…
In these study C.elagans were used as a organisms model to analysis that these mutations may have in complex organisms.In this study it was investigated how different environmental toxins and pharmacy derivatives could damage the genetic material and thus lead to numerous diseases. In this study the C.elegans were exposed to chemicals that regularly affect humans and it was found that most of these cause great damage to the DNA of these organisms. Several techniques of DNA reconstruction were also evaluated. The C.elegans in this study played a very important role because all these results found in them lead us to future studies of diseases and how to cure them in