Topical ointments
Introduction:
An ointment is semi solid topical preparation applied to external application with rubbing effect. It may be a vehicle or media for a drug or it may serve like a protective or emollient. Ointments show plastic flow characteristics. When the ointment is applied it is definite yield value and the resistant to flow drops as the applications to the skin is continued. Body:
• Uses :
There are two types of ointments:
A- Medicated: used to treat different dermatological conditions according to the incorporation drug and the skin part it can reach.
Ophthalmic ointment: used to eye infections.
B- Non Medicated: emollients (contain amount of oils) and lubricants.
• Advantages of ointments :
A- They can …show more content…
C- The used bases can impart an additional emollient or lubricant effect.
• Disadvantages of ointments:
A- They are greasy in nature state.
B- They are not easy to remove.
C- Ointments either have poor drug release or poor drug percutaneous.
• Although there are 4 bases of ointments have advantages and disadvantages classified into:
A- Oleaginous bases: contain 100% of fatty substances, no aqueous and hold of water only up to 5%.
-Advantages: Chemically inert, don't dry out on aging and have a good emollient effect.
-Disadvantages: difficult to remove, cannot apply on hairy surfaces.
-Examples: liquids paraffin and soft, hard paraffin.
B- Absorption bases: more hydrophilic than oleaginous base.
Advantages: high water absorption, better spreading and good emollient effect.
Disadvantages: difficult to remove, cannot apply to exudates area.
Examples: Anhydrous absorption bases.
C- Water removable: very hydrophilic, o/w emulsion.
Advantages: easy to remove and good …show more content…
Uses:
Use in corticosteroid responsive dermatoses complicated and/or bacterial infections, such as: 1-Atopic dermatitis 2-Seborrhoeic dermatitis 3-Lichen simplex chronicus 4-Psoriasis (particularly of the face and body folds) Allergic contact dermatitis.
Contraindications:
1-Sensitivity to any of the components of the preparation.
2- Not indicated in those patients with tuberculous lesions, topical or systemic viral infection. 3-KENACOMB is not intended for ophthalmic use, nor should it be applied in the external auditory canal of patients with perforated eardrums.
.
4- Corticosteroids have been shown to be teratogenic in animals following dermal application. As these agents are absorbed percutaneously, teratogenicity following topical application cannot be excluded. Therefore KENACOMB Ointment should not be used during pregnancy.
Side effects:
Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria
Introduction:
An ointment is semi solid topical preparation applied to external application with rubbing effect. It may be a vehicle or media for a drug or it may serve like a protective or emollient. Ointments show plastic flow characteristics. When the ointment is applied it is definite yield value and the resistant to flow drops as the applications to the skin is continued. Body:
• Uses :
There are two types of ointments:
A- Medicated: used to treat different dermatological conditions according to the incorporation drug and the skin part it can reach.
Ophthalmic ointment: used to eye infections.
B- Non Medicated: emollients (contain amount of oils) and lubricants.
• Advantages of ointments :
A- They can …show more content…
C- The used bases can impart an additional emollient or lubricant effect.
• Disadvantages of ointments:
A- They are greasy in nature state.
B- They are not easy to remove.
C- Ointments either have poor drug release or poor drug percutaneous.
• Although there are 4 bases of ointments have advantages and disadvantages classified into:
A- Oleaginous bases: contain 100% of fatty substances, no aqueous and hold of water only up to 5%.
-Advantages: Chemically inert, don't dry out on aging and have a good emollient effect.
-Disadvantages: difficult to remove, cannot apply on hairy surfaces.
-Examples: liquids paraffin and soft, hard paraffin.
B- Absorption bases: more hydrophilic than oleaginous base.
Advantages: high water absorption, better spreading and good emollient effect.
Disadvantages: difficult to remove, cannot apply to exudates area.
Examples: Anhydrous absorption bases.
C- Water removable: very hydrophilic, o/w emulsion.
Advantages: easy to remove and good …show more content…
Uses:
Use in corticosteroid responsive dermatoses complicated and/or bacterial infections, such as: 1-Atopic dermatitis 2-Seborrhoeic dermatitis 3-Lichen simplex chronicus 4-Psoriasis (particularly of the face and body folds) Allergic contact dermatitis.
Contraindications:
1-Sensitivity to any of the components of the preparation.
2- Not indicated in those patients with tuberculous lesions, topical or systemic viral infection. 3-KENACOMB is not intended for ophthalmic use, nor should it be applied in the external auditory canal of patients with perforated eardrums.
.
4- Corticosteroids have been shown to be teratogenic in animals following dermal application. As these agents are absorbed percutaneously, teratogenicity following topical application cannot be excluded. Therefore KENACOMB Ointment should not be used during pregnancy.
Side effects:
Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria