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272 Cards in this Set

  • Front
  • Back
Pathophysiology of diabetes
A disorder of glucose metabolism related to insufficient insulin.
Results from progressive destruction of pancreatic Beta cells due to an autoimmune process
___ to ____% of the ____cells of the pancreas are destroyed before there are any manifestations of diabetes
80-90%
islet
Diabetes Type 1 generally occurs in ppl ......
Generally occurs in people under 30, peak onset between 11 and 13. Incidence higher in whites than non whites and males over females
A hormone produced by the beta cells of the islets of Langerhans of the pancreas
insulin
Required hormone for glucose utilization
insulin
Continuously released in the blood stream with periods of increased release in response to food ingestion
insulin
Average insulin released is __to __ U or ___ of body weight
40-50
0.6 U/kg
Insulin maintains the glucose level between __ and ___mg/dl
70- 110
5 functions of insulin:
(promote, promote, inhibit, enhance, increase)
Promotes glucose transport from the bloodstream into the cell.
Promotes storage of glucose as glycogen in the liver and muscle
Inhibits gluconeogenesis
Enhances fat deposition in adipose tissue
Increases protein synthesis
These hormones-oppose insulin
Glucagon
Cortisol
Epinephrine
Growth hormone
by increasing the blood sugar through stimulating glucose production and output by the liver and decreasing movement of glucose into cells.
What are the 3 P's and what do they point to?
Three P’s
Polyuria
Polydipsia
Polyphagia
Diabetes Type 1 onset
What are the manifestations of diabetes?
Usually rapid once pancreas no longer functioning, slow onset otherwise
Recent, sudden weight loss
Three P’s
Polyuria
Polydipsia
Polyphagia
increased thirst
Polydipsia
Polyphagia
increased appetite
Also known as:
DKA
Ketoacidosis
Also known as Diabetic Acidosis
Ketoacidosis
Also known as Diabetic Coma
Ketoacidosis
Ketoacidosis Caused by what? And what does it cause?
lack of insulin
Hyperglycemia
Ketosis
Acidosis
Dehydration
What precipitates Ketoacidosis?
Undiagnosed diabetes
Infection
Illness
Inadequate insulin dosage
Poor compliance
Change in diet or exercise regimen
What are the steps to ketoacidosis
Insulin is not present so…
Glucos cant b used for energy
fat break down for energy
metabolism of fat > ketones
Ketones are acidic
alters PH of the blood
causing Metabolic Acidosis

High sugar content causes severe dehydration
Insulin deficiency impairs ___ synthesis and causes protein to breakdown which results in ____ loss from tissues
Insulin deficiency impairs protein synthesis
This causes proteins to break down
The break down of proteins results in nitrogen loss from tissue
Insulin deficiency Stimulates the production
of glucose (from the proteins) which further increases blood sugar
Insulin deficiency causes glucose levels to rise which leads to
osmotic diuresis
Insulin deficiency untreated may cause ___ imbalance which can lead to what?
Untreated.. leads to fluid and electrolyte imbalance
Renal failure may occur from the decreased fluid volume (hypovolemic shock).
What are the early Manifestations of Ketoacidosis?
Early-
Lethargy and weakness
Dehydration
Poor skin turgor
Dry mucous membranes
Tachycardia
Orthostatic hypotension
Thirst
Dry mouth
s/s of Ketoacidosis
Severe dehydration
Sunken eyeballs
Dry , loose skin
Abdominal pain with or without anorexia and vomiting
Kussmaul respirations
Acetone breath
Glucose >250 mg/dl,
pH <7.35,
serum bicarbonate<15 mEq/L
Fever
Urinary frequency
Ketoacidosis
Glucose ____mg/dl,
pH ____,
serum bicarbonate_____
>250
<7.35
<15 mEq/L
Interventions for Ketoacidosis
Large bore IV for IV fluids
.9% NS per MD order
Insulin therapy- IV drip- per MD order
Assess skin and mucous membranes
Monitor I & O
Monitor labs: serum glucose, acetone serum and urine specific gravity, ABG’s, Na+ and K+- as ordered by MD
Monitor VS and LOC- neurological check
Cardiac monitor- maybe hemodynamic monitoring
O2 per NC per MD order
Rapid acting Insulin
Names, onset, peak, duration
Humalog(lispro)
Aspart (Novolog)
10 min, 1 hour, 3 hours
Short acting Insulin
Names, onset, peak, duration
Regular (Humulin R, Novolin R)
1/2 -1 hr, 2-3, 4-6
Intermeadiate acting Insulin
Names, onset, peak, duration
NPH (humulin N, novolin N)&Lente
3-4, 4-12, 16-20
Very long acting Insulin
Names, onset, peak, duration
Glargine (Lantus)
1 hour, no true peak, duration 24 hours
Long acting insulin
names, onset peak duration
Ultra Lente
6-8,12-16, 16-30
Lantus (lente), how and when is it given?
given at same time each day DO NOT MIX
Current trends in diabetes treatment
Byetta (type 2 only)
Insulin pump
Jet injectors
Nasal insulin
(Exubera-type 2 only)
Skin patch
Oral insulin with enzyme control
Oral spray
How do you mix insulin?
NRRN
NPH, Reg, Reg, NPH
1st inject air in NPH then reg, then pull insulin from reg then NPH, clear to cloudy
Trends- Byetta incretin mimetics, pancreas, liver, appetite, stomach
Byetta signals the pancreas to make the right amount of insulin after you eat, it sops the liver frmo making too much glucose, may also reduce your appetie, helps to slow how quickly food and glucose leave the stomach.
Do I take my Insulin if I am sick??
yes
Take insulin or oral agent as usual
Test blood glucose and urine for ketones every 3-4 hours
Report glucose >300 mg/dl to doctor or as otherwise directed
If unable to tolerate regular meal, substitute soft foods (custard, eggs, broth) 6-8 x/day
If V/D- ½ cup broth 1 cup Gatorade every ½-1 hour and report to health care provider
Teaching Plan for diabetes
What is diabetes
What are the symptoms of high/low sugar
Medication
Diet (Refer to dietician)
Exercise
Management when ill
Foot care
Eye care
Dental care
Technique for injection
Method, frequency of glucose monitoring
Complications
Routine follow up care
DCCT
(Diabetes Control and Complications Trial)

3-4 injections per day to achieve control
Goal: maintaining blood glucose levels to as close to normal as possible prevents or slows prevention of long term complications
Allows patients to change insulin dose day to day in accordance to eating and activity pattern
DCCT, who are candidates who can't have tight control>
Persons with autonomic neuropathy (disease of autonomic nerve that causes them to have hypoglycemic unawareness) they do not experience symptoms of hypoglycemia and can be severe hypoglycemic
Persons with recurring severe hypoglycemia, target goals for glucose levels should be raised in interest of safety
Persons with permanent irreversible complications of diabetes (blindness from retinopathy or CRF) requiring dialysis as risks with intensive treatment outweigh benefits
Patients with cerebral vascular or cardiovascular complications severe hypoglycemia may trigger CVA or cardiovascular event
Patients who don’t take full responsibility for their care
Most prevalent of the diabetes, accounts for over 90% of patients with diabetes.
Type II
Usually occurs in people over 40 years old and 80-90% are overweight at the time of diagnosis.
Type II
Tendency to run in families and has a genetic basis
Type II
Native Americans 3 x and African Americans 1.7 x more likely to have Type ___ diabetes as non-Hispanic whites.
2
More than half diagnosed after age 55**Used to be called adult onset but no longer as diabetes is growing in numbers among children and adolescence
type 2
In Type II, the major pathophysiologic difference between type 1 and type 2.
The pancreas continues to produce some insulin
Insulin produced is insufficient for the needs of the body and/or is poorly utilized by the body.
type 2
Pathophysiology Three Major Metabolic Abnormalities in Type II diabetes
1. Insulin resistance develops-insulin receptors are not responsive to the action of insulin or there are not enough receptors. This impairs the entry of glucose into the cell.
2. A marked decrease in the pancreas ability to produce insulin as the Beta cells become fatigued from trying to compensate for the elevated sugar levels.
3. Inappropriate glucose production by the liver. Instead of regulating release of glucose in response to blood levels, the liver releases glucose haphazardly without response to body’s needs.
Risk Factors- Type 11
certain meds
inactivity
HTN, high chol
pregnacy
race,
stress
obsiety
age +65
family history
Diabetes Type 2 Manifestations
Not as apparent usually as Type 1
Fatigue
Recurrent infections (bacterial, vaginal yeast)
Prolonged wound healing
Visual changes
Acanthosis Nigricans
Glucose Tolerance
Test
Fasting sugar obtained, patient given 50-100g glucose, blood sugar drawn at intervals. Peak should be ½-1 hours with return to normal in 3 hours). Level of 200 mg/dl after 2 hours is diagnostic. Between 140 and 200mg is considered impaired fasting glucose and a risk factor
Fasting Glucose (FBG)
TEST
Exceeding 126 diagnostic for diabetes. Between 110 and 126 indicated impaired glucose tolerance (IGT)
Non-fasting glucose
TEST
Random greater than 200 with accompanying symptoms (polyuria) diagnostic for diabetes
Glycosylated hemoglobin (HgbA1C)
TEST
Used to determine glucose levels over time (3-4 months). Shows amount of glucose that attaches to hgb over the lifespan. Ideal for diabetic is <7%. Non diabetic 2-5%.
Diabetes Type II diet based on pyramid
Protein 10-20% of total daily calories
Fat less than 20-30% of daily calories (<10%saturated)
Cholesterol less than 300 mg/day
Carbohydrate should constitute the remaining 50-60%
Sodium less than 2400 mg/day
Fiber 25 to 30 gm/day
Added fiber in diet improves glucose tolerance due to delayed absorption. Same effect occurs with type I diabetics :will thus decrease insulin need (if required)
Alcohol sparingly. Absorbed before other nutrients. Insulin not required for absorption
Hypoglycemia risk. Be careful of interactions – diabinese causes antabuse effect. Metformin- may cause lactic acidosis
Plate method for diatetes type 2 diet
Helps visualize the amounts- 9 inch plate
Lunch and dinner one half of plate filled with nonstarchy vegetables one fourth is filled with a starch and one fourth with 2-3 oz of lean meat. A glass of skim milk and small piece of fresh fruit.
Breakfast plate filled half way with starch, one fourth an optional protein. Skim milk and a small fruit.
Meds that decrease hepatic glucose output
Biguanides Metformin (Glucphage).
Thiaxolidinediones Pioglitazone (Actos) and Rosiglitazone (Avandia)
meds that decrease glucose absorption also known as starch blockers
Alpha Glucosidase Inhibitors- Action : slows the absorption of carbohydrates in the small intestine.Taken with first bite of meal.
Acarbose (Precose) and Miglitol (Glyset)
meds that increase peripheral glucose uptake
Biguanides Metformin (Glucphage).
Thiaxolidinediones Pioglitazone (Actos) and Rosiglitazone (Avandia)
meds that increase insulin secretion
Sulfonylureas- Action is to increase insulin production from the pancreas. Generally more effective early in course.
Examples: 2nd generation Glipizide (glucotrol), glyburide (Micronase, DiaBeta, Glynase), Glimepiride (Amaryl)
Meglitinides-Action also to increase insulin production from the pancreas. However action is more rapid. When taken just before a meal increase pancreatic secretion of insulin mimicking the normal response.
Examples: Nateglinide (Starlix) and Repaglinide (Prandin)
What meds have an Action that increases insulin production from the pancreas. Generally more effective early in course.
Sulfonylureas
Glipizide (glucotrol), glyburide (Micronase, DiaBeta, Glynase), Glimepiride (Amaryl)
Action to increase insulin production from the pancreas. However action is more rapid. When taken just before a meal increase pancreatic secretion of insulin mimicking the normal response.
Meglitinides
Nateglinide (Starlix) and Repaglinide (Prandin)
These medications action is to reduce glucose production by the liver. It also enhances insulin sensitivity at the tissue level and improves glucose transport into the cell.
Biguanides
Metformin (Glucphage).
These medications action is to improve insulin sensitivity, transport and utilization. Will not cause hypoglycemia as they do not increase insulin production.
Thiaxolidinediones
Pioglitazone (Actos) and Rosiglitazone (Avandia)
What medication is also known as starch blockers. Action : slows the absorption of carbohydrates in the small intestine.Taken with first bite of meal.
Alpha Glucosidase Inhibitors-
Acarbose (Precose) and Miglitol (Glyset)
What medications may mask the symptoms of hypoglycemia and prolong the hypoglycemia effects of insulin
beta blockers, Metropolol, Toprol, Atenolol, Inderal
What medications can cause hyperglycemia because of the potassium loss. (Remember, K+ helps bring glucose into the cell)
Thiazide and loop diuretics (Lasix, HCTZ)
What is the effect of exercise on Type II?
Regular consistent (time, amount) exercise
Increases insulin sensitivity and has a direct effect on lowering glucose levels. Promotes weight loss and insulin resistance. Improves circulation and muscle tone. Raises HDL, lowers LDL
Weight loss may be the only treatment required for type II
Glucose lowering effects can last up to 48 hours after activity
Schedule 1 hour after a meal or have snack 10-15 g cho before
Monitor glucose levels before, during and after
ALSO: strenous exercise may increase glucose levels
Foot care cont'd
Do not wear new shoes longer than 2 hours
Bath daily, watching skin folds
Foot care as discussed, notify health care provider if wounds present
Dental cleaning every 6 months, daily brushing and flossing. Inform dentist of condition.
Causes of hypeglycemia
Causes: Too much food
Too little or no diabetic medication
Inactivity
Emotional, physical stress
Poor absorption of insulin
Symptoms of hypeglycemia
3 P's, dry skin, b.urred vision, nausea, drowsiness
Causes of hypoglycemia
Alcohol without food –reduces gluconeogenesis
Too little food- delayed or omitted
Too much diabetic medication
Too much exercise without compensation
Diabetes med or food taken at wrong time
Loss of weight without change in medication or diet
Use of beta blockers masking symptoms
Symptoms of hypoglycemia
shaking, fast HR, sweating, hunger, impaired vision,
dizziness, anxious
Chronic complications of Type 2 diabetes
stroke, eye damage, heart attack, kidney damage, impotancey, numbness
A complication Specific to diabetes
Microvascular- (capillaries and arterioles)
Generally occur 10-20 years
Diabetic retinopathy (other eye changes: cataracts, lens changes, visual disturbances, extraocular muscle palsy, glaucoma)
Nephropathy
Neuropathy
complications for diabetes type 2, large and small
Macrovascular- (large and medium blood vessels)
Macrovascular- (large and medium blood vessels)
Prevent macro vascular complications by
Quitting smoking
Tight glycemic control
Maintaining normal lipid values
Low fat diet, medications
Weight loss
Control of hypertension
Exercise
15 years nearly all type 1 and 80% type II will have. Most common cause of blindness in 20-74 y/o
Retinopathy
Occurs as a result of micro hemorrhage, leaking.
Treatment- prevent blindness with regular eye exams (dilated) as there are no symptoms until blindness
Treat vessels with cryotherapy, biectomy, photocoagulation with laser
Risks same for type I and II
Leading cause of End Stage Renal Disease (ESRD) in the US
Risk factors HTN, smoking, genetic predisposition and hyperglycemia
Occurs as a result of damage to the small blood vessels that supply the glomeruli of the kidney.
Nephropathy occurs because
Occurs as a result of damage to the small blood vessels that supply the glomeruli of the kidney
Treatment to prevent-
Nephropathy
ACE inhibitors (Lisinopril, Enalapril) or ARB (Cozaar, Hyzar) due to its kidney protective effect. 1st choice for patients with HTN, given even in patients without hypertension
Yearly screening for microalbumin in urine> If present 24 hour urine for protein, creatinine clearance
a problem in peripheral nerve function (any part of the nervous system except the brain and spinal cord) that causes pain, numbness, tingling, swelling, and muscle weakness in various parts of the body. ...
Neuropathy
Nerve damage that occurs possibly as a result built up _____and ____
sorbitol and fructose.
(the most common) type of Neuropathy
Sensory neuropathy
Effects the hands and feet causing paresthesias (pain, burning, numbness, tingling, itching, sometimes hyperesthesia- skin very sensitive**Story Time:Amy)
Treatment- Control of blood sugar. May use meds to control the pain
Antiseizure:gabapentin- (neurontin), Lyrica
Tricyclic antidepressants: amitriptyline (Elavil)-Inhibits neurotransmitters serotonin and norepinephrine- transmit pain
Capsaicin (Zostrix)- depletes accumulating pain mediating chemicals
Can affect nearly all body systems and lead to hypoglycemic unawareness, bowel incontinence, urinary retention, delayed gastric emptying, erectile dysfunction
Autonomic neuropathy-
Hyperglycemic Hyperosmolar Nonketotic Syndrome (HHNS)
Life threatening syndrome that can occur in the patient with diabetes that is still able to produce some insulin. Because some insulin is released, DKA does not occur but there is not enough insulin to prevent hypergylcemia leading to osmotic diuresis and extracellular fluid volume depletion (celluar dehydration)
Usually precipitated by illness, physiological stress, some medications (thiazides)
Glucose of >600 mg/dL
Glucose metabolism in pregnant diabetic
Insulin requirements increase
Placenta produces human placental lactogen (HPL)an insulin antagonist.
Placental enzyme insulinase accelerates breakdown of insulin
Rate of glucose in kidney is increased which reduces the renal threshold for glucose
______ amniotic fluid greater than normal.Occurs 10X more in diabetic pregnancies. Causes premature rupture of membranes, pre-term labor
Hydramnios (polyhydramnious)
Most often occurs in 2nd or 3rd trimester often caused by maternal infection or illness
Ketoacidosis
Fetal/Neonatal risks and complications of the infant
Macrosomia- Infant > 4000 g. 25-42% of pregnancies
Increases in maternal serum and urine after 2 months of pregnancy and continues at high levels until term.
Estriol levels-
Gestational diabetes
Develops during pregnancy
Usually detected 24-28 weeks of gestation
Normal glucose levels within 6 weeks postpartum
Risk of developing type II diabetes in 5-10 years is increased
Diet is generally the treatment,may need insulin
Pre-gestational diabetic
Not related to pregnancy
Glucose levels do not return to normal post partum without treatment
Hereditary
Effects of surgery on blood glucose and resultant insulin therapy
Stress may increase the glucose
Monitor blood glucose
Tests prior to C-Section
Type and cross match or auto transfusion??
Ultrasound
Blood sugar
Cover BS with SSI
Too much insulin to available glucose =
hypglycemia
BS < 50mg/dL
hypoglycemia
Too much glucose to insulin in the blood
hyperglycemia
who has the highest risk factor for type I diabetes
white males
osmotic diuresis has what manifestations
3 P's
poly:
uria
dipsia
phagia
Which of the following statements about Type I diabetes vs. Type II diabetes is not true?
The Type I diabetic will require insulin for control
The onset of Type I diabetes is generally more rapid
Obesity is more often a predisposing factor in Type II diabetes
Type II diabetics are more prone to develop ketoacidosis
Type II diabetics are more prone to develop ketoacidosis
Select the false statement(s) about the pathophysiological basis of the symptoms of diabetes:
Answer
Polyphagia and weight loss occur because insulin deficiency impairs metabolism of protein and fats
Polyuria occurs because the thirsty diabetic increases fluid intake
Hyperglycemia produces diuresis
All are false
All are false
Select the true statements about diabetic ketoacidosis:
Answer
It may be caused either by overeating or by forgetting to take insulin
Blood glucose is elevated
Symptoms include fruit-smelling breath
All of the above
ALL
Which nursing measures would be inappropriate for the client in diabetic/ketoacidosis?
Answer
Starting an IV as prescribed
Observing vital signs and level of consciousness frequently
Injecting Glucagon IM
All are inappropriate
Injecting Glucagon IM
During treatment of diabetic ketoacidosis:

Answer
The aim of fluid and electrolyte therapy is to replace water and correct electrolyte deficits.

Insulin drives K+ from the blood back into the cells

Both of the above
both
The diagnosis of diabetes mellitus may be confirmed by this sensitive diagnostic test:
Answer
Glucose tolerance test
Fasting blood sugar
Two-hour postprandial blood sugar
Urine test for glucose and acetone
glucose tolerance test
The client who is scheduled for a fasting blood sugar should be told that he:
Answer
Must have nothing by mouth except water for 16 hours before a blood sample is drawn
Will be asked to drink a concentrated glucose solution
Should void when the test starts and again when it ends
None of the above
none of the above
client is given NPH insulin at 7 AM each day before breakfast. The peak of its effect is likely to occur:
Answer
At 8:00 a.m.
Late in the afternoon
After midnight
Before breakfast the next day
late in afternoon
Select the FALSE statement(s) about oral antidiabetic agents of the Sulfonylurea type:
Answer
They stimulate the beta cells of the pancreas to secrete insulin
Insulin dependent diabetics can easily switch to these drugs
Side effects include hypoglycemia
All of the above are false
Insulin dependent diabetics can easily switch to these drugs
Which statement would be inappropriate to include in a teaching plan for the client who is taking an oral hypoglycemic agent of the sulfonylurea group?
Answer
They are contraindicated during pregnancy
They may interact adversely with alcohol
It is no longer necessary to adhere to a diabetic diet
it is no longer necessary for diabetic diet
Which statement is true about nutrition for a diabetic::
Answer
The American Diabetes Association endorces a specific meal plan

The goal is healthy eating

The diabetic diet is very different than two the diet of a nondiabetic diet
healthy eating
Which statement is true?

Answer
Diet and insulin is necessary for glucose control for a type 2 diabetic

Bedtime snack is not usually necessary for a type 1 diabetic

Consistency in daily intake is necessary for glucose control for a type 1 diabetic
Consistency in daily intake is necessary for glucose control for a type 1 diabetic
Macrovascular complications are thought to be a basis for which long-term complications of diabetes:
Answer
Cerebrovascular disease
Cardiovascular disease

Peripheral vascular disease
All of the above
all of the above
The diabetic should know that, on days when he is sick, he should:
Answer
Omit daily insulin dosage
Reduce usual daily insulin dosage by half
Test blood glucose every 4 hours to detect need for additional insulin
Test blood glucose every 4 hours to detect need for additional insulin
Babies of diabetic mothers tend to be:
Answer
Low birth weight, hyperglycemic
Prone to respiratory distress, low birth weight, immature
Excessively large, prone to respiratory distress, hypoglycemic
Excessively large, postmature, diabetic
Excessively large, prone to respiratory distress, hypoglycemic
When a diabetic undergoes surgery, which problem may occur:
Answer
Stress may raise the blood sugar and increase the need for insulin
Infection or fever may lower the blood sugar and decrease the need for insulin
Impaired circulation may lead to increased wound healing
stress may increase BS
Factors involved in insulin deficiency in the diabetic include:
Answer
Impaired production of pancreatic insulin
Insufficient insulin secretion in proportion to blood glucose levels
Insulin resistance

All of the above
all
Which of the following statements about Type I diabetes vs. Type II diabetes is true?
Answer
Type I diabetes usually can be controlled with oral hypoglycemic drugs
Most Type I diabetics have rather stable blood glucose levels
Type II diabetics usually have some functioning islets of Langerhans
Type II diabetes is usually diagnosed in the twenties
Type II diabetics usually have some functioning islets of Langerhans
Select the false statement about insulin reaction:
Answer
It may be caused by skipping a meal
There is too much insulin in the blood in relation to the amount of available glucose
Occurs midmorning
midmorning
During treatment of diabetic ketoacidosis:
Answer
The aim of fluid and electrolyte therapy is to replace water and correct electrolyte deficits

Insulin drives K+ from the blood back into the cells

Both of the above
both
In evaluating the results of an oral glucose tolerance test, you should know that, in the nondiabetic individual, the blood glucose level will:
Answer
Elevate and then return to less than 140 mg/dl in 2 hours
Elevate and then return to fasting level in four hours
Show very little change from fasting level
Drop noticeably and then gradually rise over two hours
Elevate and then return to less than 140 mg/dl in 2 hours
The usual procedure for a glucose tolerance test includes:
Answer
High carbohydrate diet for several days before the test
Drinking a concentrated carbohydrate solution after the fasting blood sample is taken
Obtaining a blood specimen fasting and at one, two, and three hour intervals after the test starts
All of the above
all of the above
Select the FALSE statement about oral antidiabetic agents:
Answer
They can produce hypoglycemic reactions
Are effective for selected diabetics
They are a form of insulin which can be taken orally
form of oral insulin
Microvascular complications include:
Answer
nephropathy (kidneys)

retinopathy (eyes)

dermopathy (skin)

All of the above
all
The diabetes control and complications trial of 1993 validated:
Answer
All diabetic clients benefit from tight control of blood glucose
Importance of urine testing for glucose level information
No effect with control of blood glucose during pregnancy
Importance of goal of maintaining a lower glycosated hemoglobin level
Importance of goal of maintaining a lower glycosated hemoglobin level
When testing the blood with a blood glucose monitor, the nurse should be aware that:
Answer
A small drop of blood covering 1/4 the pad is adequate
the results are often inaccurate
Blood samples should be taken p.c.
None of the above
none
In regard to rest and exercise, the diabetic should be taught that:
Answer
Physical exercise should be minimized because it interferes with glucose utilization
Insulin dosage must be increased on heavy exercise days
A regular pattern of rest and exercise should be followed as much as possible each day
regular rest and exercise
Select the true statement about diabetes and pregnancy:
Answer
Most diabetic women are infertile or abort early on in pregnancy
Diabetics are more likely than nondiabetics to suffer from toxemia and hydramnios
Women with gestational diabetes will have serious visual and renal impairment as a result of pregnancy
A cesarean section is recommended at 30 weeks for early delivery of a diabetic mother's baby
Diabetics are more likely than nondiabetics to suffer from toxemia and hydramnios
When the insulin-dependent diabetic undergoes surgery, you would anticipate that he would post operatively receive:
Answer
Regular insulin subcutaneous according to a sliding scale
NPH insulin subcutaneous in usual dose
NPH insulin IV mixed in a bottle of 5% D/W
No insulin while NPO
regualr sliding scale
Largest gland in the body
liver
Functions of the Liver
Glucose metabolism
Ammonia conversion- to urea- kidneys remove
Protein metabolism
Clotting- Synthesizes clotting factors
Albumin-Synthesizes plasma proteins
Fat metabolism
Cholesterol synthesis
Vitamin and iron storage
Bile formation
Bilirubin excretion
Symptoms of Liver Dysfunction
Jaundice
Fatigue
Pruritus
Abdominal pain
Fever
Anorexia
Vitamin deficiencies
Weight gain/Edema
Increasing abdominal girth
Hematemesis
Melena
Easy bruising/bleeding
Sleep disturbance
Hepatitis A is caused by what
Fecal-Oral
has vaccine
crowded, contaminated food
hep B etiology, transmission, prevention
from exposure tobody fluids, saliva
vaccine
can overcome
Hep C
IV drug use most common, body fluids chronic liver disease Increased cancer
The edema causes RUQ pain and the liver is enlarged, what disease is it?
hepatitis
Diagnostic Evaluation for hepatitis.
Bleeding times (PT/PTT) high
Serum and urine bilirubin
Total serum protein-Decreased
Serum albumin- Decreased
- ALK Pho high
AST high
ALT high
Ammonia high
antigen antibody test
Why is a pt susceptible to hemorrhage with hepatitis?
PT is increased. Liver responsible for the manufacture of clotting factors and the liver is not in proper working order
Nursing care to include: Good skin care, careful mouth care, small bore needles (minimize IM), check for bleeding gums
Why is a pt susceptible to pruiti with hepatitis?
Pruritis develops as a result of increased bile salts in the blood.
Diet, type? Rationale? Problems, with hepatitis
High protein- For liver cell regeneration. Protein may be restricted when liver function is decreased due to decreased ability of liver to metabolize protein byproducts
High carbohydrates-Restore glycogen stores
Low fat- Bile salts released in effort to break down fat
Increase calorie- To counteract weight loss
Small, frequent meals- Early satiety due to RUQ fullness
Fluid intake of 2500-3000 mL per day
Carbonated beverages and avoidance of very hot or cold foods may help anorexia
interventions for heptatits pt
bedrest during icteric phase to increase liver cell regeneration and reduce meabolic demands, drugs entiemetics, NO COMPAZINE
drug treatment for hepatitis
reverse transcripatse inhibitors Epvie or Hepsera, treats chronis HBV, alpha interferon 3x/wk for 6months, remission
antiviral agent- ribaviran
Type B hep recovery is
3-4 months or longer, 10% can die or develop chronic hep
Phsychological stress of hep
icterus-body image, isolation from others
prevent hep
No alcohol or raw shellfish?
Functions of the Gallbladder
Storage deposit for bile
Between meals with sphincter of Oddi closed, bile produced by the liver, enters the gallbladder.
During storage, a large amount of water in the bile is absorbed through the wall so the bile is 5-10x more concentrated.
When food enters the duodenum, the gallbladder contracts, sphincter of Oddi relaxes and bile enters the intestine.
Capacity of gallbladder is 30-50 mL
Two types of gall bladder stones
Pigment stones 25%,
Cholesterol stones (most common)- Cholesterol is the normal constituent of bile and is insoluable in water. 75% of time. . In gallstone prone clients there is a decrease in bile acids, and increase in cholesterol synthesis, resulting in bile supersaturated with cholesterol resulting in stone formation and inflammation due to irritation
Risk factors for Gallstones
5 F's
fat
female
family history
forty
flatulent
Gallstones obstruct the bile duct causing
jaundice, nausea and vomiting, RUQ pain radiating to the back, right shoulder and scapula. Clay colored stools due to lack of bile pigments. Urine dark from excretion of bile pigments
Gallstone Symptoms occur
primarily after a meal high in fat/fried foods when bile is trying to be released to break down the fat
Symptoms of chronic cholecystitis include
a history of fat intolerance, dyspepsia, heartburn and flatulence, vitamin deficiency
Acalulous Cholecystitis thought to be caused from what?
Inflammation unrelated to obstruction by stone. May occur after major surgery, trauma. Believed to be caused by change in fluid/electrolytes and bile stasis.
Labs for gallstones
high WBC, ALT, AST, Alk Phos,
Objective assessment for gallstones
-Fever, restless, jaundice, icteric sclera, diaphoresis, tachypnea, splinting during respirations, tachycardia, abdominal gaurding and distention. May have elevated liver enzymes, bilirubin (serum and urine), elevated WBC, abnormal GB ultrasound
Non surgical procedures to treat cholelithiasis
Nutritional and supportive therapy- IV, NG, pain med, antibiotics. Low fat liquid diet. Surgical tx held off until acute symptoms subside if possible.
ERCP- to remove stones
Medications that dissolve cholesterol stones
(Ursodeoxycholic acid (UDCA) and chendeoxycholic acid (chenodiol or CDCA)
Cholesterol solvents methyl tertiary terbutyl (MTBE)- through catheter or during ERCP
Laproscopic cholelithiais nursing interventions post op
Pain
Place in left Sims position to help move gas pocket away from diaphragm (causing irritation of phrenic nerve)
PC: Bleeding R/L decreased Prothrombin production
Risk for ineffective breathing pattern R/T pain
Encourage deep breathing
Encourage early ambulation and movement
Knowledge deficit
Common to have referred pain to shoulder- from CO2
what is a Choledochostomy-
Incision in common bile duct for removal of stones. Tube inserted in duct for drainage of bile until edema subsides
what is a Cholecystostomy
Cholecystostomy-Gallbladder is opened, stones, bile and pus are removed. T-Tube is inserted to ensure ductal patency. Trauma to the common bile duct stimulates inflammation which can impede bile flow and contribute to bile stasis.
Thyroid hormones affect many vital body functions what are they
HR, RR,
rate for calorie burn,
skin maintenance
heat production,
fertility
digestion
What is the second most common disease after diabetes?
hypethyroidism
Produces and stores 3 hormones:
Thyroxine (T4)
Triiodothyroinine (T3)
Calcitonin (lowers plasma calcium level by increasing deposition in bone)
What is essential to the thyroid for production of the 3 hormones
iodine
Secretion of T3 and T4 occur in response to
TSH levels
DIscharge teaching for hypothyroid patient in regard to medications
Medication- Levothyroxine (synthroid) must take on empty stomach at same time daily
Grave disease also known as
hyperthyroidism
manifestations of hyperthyroid, or thyrotoxicsosi
Nervousness
Hyperexcitability
Irritable, apprehensive
Palpitations, increased HR
Poor toleration of heat
Flushed skin
Warm, soft, moist skin
Fine tremor
Exophthalmos
Cirrhosis is a chronic disease characterized by
replacement of normal liver tissue with diffuse fibrosis that disrupts the structure and function of the liver.
Functions of the Liver- REMEMBER
Glucose metabolism
Ammonia conversion- to urea- kidneys remove
Protein metabolism
Clotting- Synthesizes clotting factors
Albumin-Synthesizes plasma proteins
Fat metabolism
Cholesterol synthesis
Vitamin and iron storage
Bile formation
Bilirubin excretion
Manifestations late of cirrhosis
Late-Result from liver failure and portal hypertension
Jaundice and pruritis-
Skin lesions (spider angiomas)
Hematologic problems –increased clotting times/vitamin K def
Gastrointestinal varicies from increased pressure (portal hypertension)
Malnutrion-lack of vitamin storage
Edema- lack of albumin
Ascites- Protein rich fluid accumulates in peritoneal cavity further worsened by hyperaldosterone leading to sodium and water retention and potassium loss
Endocrine problems due to inability to metabolize hormones (Men- gynecomastia, loss of axillary and pubic hair, testicular atropy and impotence. Women-menstrual changes)
Infection and peritonitis
Mental deterioration- rising ammonia levels
Laboratory tests for cirrhosis
AST- Elevated with liver cell damage
ALT-Elevated with liver cell damage
LDH (lactate dehydrogenase) LDH 4 and 5 more specific to liver damage
Bilirubin Elevated
(direct (conjugated-soluble)and indirect (unconjugated-protein bound)
Ammonia level –Elevated
Byproduct of protein metabolism- converted to urea in the liver (normally functioning liver)
Prothrombin time- Prolonged in liver disease
Total protein (albumin decreased and globulins-increased)
Albumin-Decreased
Electrolytes-High sodium, low potassium
Medications for liver cirrohisis
Aldactone (Spirolactone)-aldosterone blocking agent, helps prevent K+ loss and promote diuresis
Vitamin K 10 mg IM- Deficient absorption of vitamin K from GI tract, prevent hemorrhage as liver cells have problem making prothrombin
Thiamine 40 mg daily- common vitamin deficiency causing polyneuritis, beriberi, Wernicke-korsakoff psychoses
Multivitamin- 1 tablet- inadequate storage of A,D,E,K
Lactulose (Cephulac) 5 mL po- reduce blood ammonia levels, promotes excretion of ammonia in stool. Side effect diarrhea **sometimes used for therapeutic effect of diarrhea
Assessment -Cirrhosis
Alcohol intake, other drugs
Skin and eye color- jaundiced from increase in bilirubin
Bleeding- check stools, urine, skin
Mentation- Check for hepatic encephalopathy
Diet history
Level of comfort- pruritis, abdominal pain, edema
Fluid and electrolyte –Weight/abd girth
Complications of liver problems
Portal hypertension
Ascites
Esophageal varices
Hepatic encephalopathy and coma
Asterixis
Fector hepaticus
Bleeding
Hepatorenal Syndrome (HRS)
Portal hypertension along with liver decompensation results in systemic vasodilation and decreased arterial blood volume
Vitamin deficiency
Metabolic abnormalities
Pruritus and skin changes
Ascites – WHY?
Portal hypertension causes resistance of blood flow through liver
Weeping of protein rich lymph from liver blocks lymph channel
Decreased oncotic pressure from lack of albumin
Hyperaldosteronism-From decreased renal blood flow causes increase in sodium and water retention
Impaired water excretion from decreased renal vascular flow and excessive ADH
Nursing Interventions for paracentesis, treatment for ascites
Pre
Ensure patient has voided (bladder decompression)
Obtain sterile equipment
Obtain consent
During
Patient in upright position edge of bed
B/P cuff on arm
Trocar introduced by MD and fluid drained
Observe for vascular collapse (pallor, increased HR, decreased b/p)
Post
Patient comfortable
Record amount, characteristic of fluid and send to lab
A nurse develops a plan of care for a client with hyperthyroidism and includes which of the following in the plan?
A. Provide small meals
B. Provide extra blankets
C. Provide a high-fiber diet
D. Provide a restful environment
restful environment
A nurse is performing an assessment on a client following a thyroidectomy. The nurse notes that the client has developed hoarseness and a weak voice. Which nursing action is most appropriate?

A. Notify physician immediately
B. Reassure the client that this is usually a temporary condition
C. Check for signs of bleeding
D. Administer calcium gluconate
normal finding
A client is admitted to an emergency room, and a diagnosis of myxedema coma is made. Which action would the nurse prepare to carry out initially?

Warm the client
Administer fluid replacement
Maintain an airway
Administer thyroid hormone
airway
A client is taking NPH insulin daily every morning. The nurse
Instructs the client that the most likely time for a hypoglycemia reaction to occur is

2 to 4 hours after administration
6 to 14 hours after administration
16 to 18 hours after administration
18 to 24 hours after administration
6-14
A nurse is preparing a teaching plan for a client with diabetes mellitus regarding proper foot care. Which instruction is included in the plan?

Soak feet in hot water
Apply a moisturizing lotion to dry feet but not between toes
Always have a podiatrist cut your toenails; never cut them yourself.
Avoid using a mild soap on the feet
lotion not betweentoes
A client is brought to the emergency room in an unresponsive state, and a diagnosis of hyperglycemic hyperosmolar nonketotic syndrome is made. The nurse would prepare immediately to initiate which of the following anticipated physician’s orders?

100 units of NPH insulin
Endotracheal intubation
Intravenous replacement of sodium bicarbonate
Infusion of normal saline
infuse normal saline
A client with a diagnosis of diabetic ketoacidosis (DKA) is being treated in an emergency room. Which finding would a nurse expect to note as confirming this diagnosis?

Elevated blood glucose level and a low plasma bicarbonate
Deceased urine output
Increased respirations and an increase in pH
Comatose state
Elevated sugar and low bicarb thus acidosis
A nurse provides instructions to a client newly diagnosed with type I diabetes mellitus. The nurse recognizes accurate understanding of measures to prevent diabetic ketoacidosis when the client states:

“I will stop taking my insulin if I’m too sick to eat.”
“I will decrease my insulin dose during times of illness.”
“I will notify my physician if my blood glucose level is greater than 250 mg/dL.”
“I will adjust my insulin dose according to the level of glucose in my urine.”
notify doc
A client is admitted to a hospital with a diagnosis of diabetic ketoacidosis (DKA). The initial blood glucose level was 950mg/dL. A continuous intravenous infusion of regular insulin is initiated along with intravenous rehydration with normal saline. The serum glucose level is now 240 mg/dL. The nurse would next prepare to administer which of the following?

Intravenous fluids containing 5% dextrose
NPH insulin subcutaneously
An ampule of 50% dextrose
Phyentyoin (Dilantin) for the prevention of seizures
During treatment of DKA, when the blood glucose falls below 250 to 300 mg/dL, the infusion rate is reduced and 5% dextrose is added to maintain a blood glucose of about 250mg/dL or until the patient recovers from ketosis.
A physician prescribes levothyroxine sodium (Synthroid), 0.15 mg PO daily, for a client with hypothyroidism. A nurse will prepare to administer this medication

Three times a day in equal doses of 0.5 mg each to ensure consistent serum drug levels
In the morning to prevent sleeplessness
Only when the client complains of fatigue and cold intolerance
At various times during the day to prevent tolerance from occurring.
morning
A nurse is caring for a client admitted to the emergency room with diabetic ketoacidosis (DKA). In the acute phase the priority nursing action is to prepare to

Administer regular insulin intravenously
Administer 5% dextrose intravenously
Correct acidosis
Apply an electrocardiogram monitor
administer regualr insulin
A client with type II diabetes mellitus has a blood glucose of greater than 600 mg/dL and is complaining of polydipsia, polyuria, weight loss and weakness. A nurse reviews the physician’s documentation and would expect to note which of the following diagnoses?

Diabetic Ketoacidosis (DKA)
Hypoglycemia
Hyperglycemic, hyperosmolar nonketotic syndrome (HHNS)
Pheochromocytoma
C HHNS
A nurse is interviewing a client with type II diabetes mellitus. Which statement by the client indicates an understanding of the treatment for this disorder?

“ I am taking oral insulin instead of shots.”
“The medications I’m taking help to release the insulin I already make.”
“By taking these medications, I am able to eat more.”
“When I become ill, I need to increase the number of pills I take.”
Sulfonyureas help to stimulate the beta cells to produce insulin
A nurse is caring for a client with type I diabetes mellitus. Which client complaint would alert the nurse to the presence of possible hypoglycemic reaction?

Hot, dry skin
Muscle cramps
Anorexia
Tremors
tremors
A client who is currently taking levothyroxine sodium(Synthroid) complains of cold intolerance, constipation, dry skin, weight gain, and puffy eyes. Based on these findings, the nurse would anticipate which of the following prescriptions?

Increase levothyroxine sodium dosage after checking the T4 level
Decrease levothryroxine sodium dosage after checking the T 4 level
Discontinue levothyroxine sodium because the client is having an adverse reaction
No change in medication as these are common side effects and will diminish with time.
increase levothyroine
A client with diabetes mellitus visits a health care clinic. The client’s diabetes mellitus previously had been well controlled with glyburide (DiaBeta), 5 mg PO daily, but recently the fasting blood glucose has been running 180 to 200 mg/dL. Which medication, if added to the client’s regimen, may have contributed to this change?

Prednisone (Deltasone)
Atenolol (Tenormin)
Phenelzine (Nardil)
Allopurinol (Zyloprim)
prednisone
A hospitalized patient with type I diabetes mellitus received NPH and regular insulin 2 hours ago (at 7:30 am). The patient calls the nurse and reports that he is feeling hungry, shaky, and weak. The client ate breakfast at 8 am and is due to eat lunch at noon. List in order of priority the actions that the nurse would take, with # 1 being first
___Give the client ½ cup of fruit juice to drink
___Check the client’s blood glucose level
___Take the client’s vital signs
___Give the client a small snack of carbohydrate and protein
___Document the client’s complaints, actions taken and the outcome
Check glucose level
Administer juice
Check vital signs
Administer snack
Document
The nurse is performing an abdominal assessment. The nurse performs which assessment technique first?

Auscultation
Inspection
Palpation
Percussion
inspec
The nurse is assessing a client 24 hours following a cholecystectomy. The nurse notes that the T- Tube has drained 750 mL of green-brown drainage. Which nursing intervention is most appropriate?

Notify the physician
Document the findings
Irrigate the T-Tube
Clamp the T-Tube
Normal finding for output to be 500-1000 first 24 hours
The nurse is reviewing the record of a client with a diagnosis of cirrhosis and notes that there is documentation of asterixis. To assess for presence of this sign, the nurse would do which of the following?

Ask the client to extend the arms
Assess for the presence of Homan’s sign
Instruct the client to lean forward
Measure the abdominal girth
extend arms
The client with ascites is scheduled for a paracentesis. The nurse is assisting the physician in performing the procedure. Which of the following positions will the nurse assist the client to assume for this procedure?

Supine
Left side-lying
Right side-lying
Upright position
upright with BP cuff on
The nurse is reviewing the laboratory results in a client with cirrhosis and notes that the ammonia level is elevated. Which of the following diets would the nurse anticipate would most likely be prescribed for this client?

High-carbohydrate
Moderate fat
High protein
Low protein
low protein
The client is admitted to the hospital for treatment of acute hepatitis B. Which activity order would the nurse expect to be prescribed?

Bedrest
Encourage ambulation
Out of bed in a chair
No activity restrictions
br
The physician has determined that the client with hepatitis has contracted the infection from contaminated food. The nurse understands that this client is most likely experiencing what type of hepatitis?
A. Hepatitis A
B. Hepatitis B
C. Hepatitis C
D. Hepatitis D
a
A client is suspected of having hepatitis. Which diagnostic test results will assist in confirming this diagnosis?

Decreased erythrocyte sedimentation rate
Elevated serum bilirubin
Elevated hemoglobbin
Elevated blood urea nitrogen
Elevated serum bilirubin
The nurse is evaluating the effect of dietary counseling on the client with cholecystitis. The nurse would evaluate that the client understands the instructions given if the client stated that which of the following food items is acceptable in the diet?

Baked scrod
Sauces and gravies
Fried chicken
Fresh whipped cream
fish
The nurse would assess the client experiencing an acute episode of cholecystitis for pain that is located in the right

Upper quadrant and radiates to the left scapula and shoulder
Upper quadrant and radiates to the right scapula and shoulder
Lower quadrant and radiates to the umbilicus
Lower quadrant and radiates to the back
Right upper quadrant pain radiating to right shoulder and scapula due to phrenic nerve irritation
The client with cirrhosis is beginning to show signs of hepatic encephalopathy. The nurse would plan a dietary consult to limit the amount of which of the following ingredients in the client’s diet?

Fat
Carbohydrate
Protein
Minerals
protein
The client with cirrhosis complicated by ascites is admitted to the hospital. The client has stated a 10 lb weight gain over the last week and a half. The client has edema of the feet and ankles. The abdomen is distended, taut, and shiny with striae. The nurse would select which of the following as the most appropriate nursing diagnosis for this client?

Imbalanced nutrition: more than body requirements
Impaired gas exchange
Risk for impaired skin integrity
Excess fluid volume
EFV
The client with hepatitis is scheduled for a liver biopsy. The nurse implements which of the following to assess for the most common symptom of bile peritonitis following the liver biopsy?

Monitoring for bloody diarrhea
Assessing for rebound tenderness
Assessing for increased flatulence
Monitoring for abdominal pain
ab pain
The client is admitted to the hospital with viral hepatitis, complaining of “no appetite” and “losing my taste for food.” To provide adequate nutrition, the nurse would instruct the client to

Eat a good supper when anorexia is not as severe
Eat less often, preferably only three large meals daily
Increase intake of fluids including juices
Select foods high in fat
increase fluids and juice
A client has developed hepatitis A after eating contaminated oysters. The nurse assesses the client for which of the following?

Dark stools
Left upper quadrant discomfort
Malaise
Weight gain
malaise
The nurse is caring for a black client who has a diagnosis of acute viral hepatitis. The nurse assesses for jaundice by checking which specific area?

Flexor surface of the extremities
Hard palate of the mouth
Nailbeds
Skin
Jaundice occurs in the skin and mucous membranes. In light skinned persons, jaundice is first seen in the sclera of the eyes and later in the skin. In dark-skinned persons, jaundice is observed in the inner canthus of the eyes and hard palate of the mouth. Pallor is detected in nailbeds and flushing from temperature is noted in the flexor surfaces of the extremities.
The nurse should evaluate results of which of the following laboratory tests for a client who has cirrhosis in order to plan for safe care?

Prothrombin time
Urinalysis
Serum lipase
Serum troponin
Prothrombin time
Many clotting factors are produced in the liver, including prothrombin
The nurse caring for a client with hemolytic jaundice anticipates which of the following findings on the laboratory results?

Elevated serum indirect bilirubin
Decreased serum protein
Elevated urine bilirubin
Decreased urine pH
Elevated serum indirect bilirubin
Obstruction to portal blood flow causes a rise in portal venous pressure resulting in splenomegaly, ascites, and dilation of collateral venous channels predominantly in the paraumbilical and hemorrhoidal veins, the cardia of the stomach and extending into the esophagus. Bleeding gums would indicate insufficient vitamin K production in the liver. Muscle wasting, commonly accompanies the poor nutritional intake commonly seen in clients with cirrhosis. Hypothermia is an unrelated finding.
A client was admitted to the hospital with cholelithiasis the previous day. Which of the following new assessment findings indicates to the nurse that the stone has probably obstructed the common bile duct?

Nausea
Elevated cholesterol level
Right upper quadrant (RUQ) pain
Jaundice
jaundice
Nausea and RUQ pain occur in cystic duct disease, but obstruction of the common bile duct results in reflux of bile into the liver, which produces jaundice. Alkaline phosphotase increases with biliary obstruction but cholesterol level does not increase.
The nurse caring for a client with uncomplicated cholelithiasis anticipates that the client’s laboratory test results will show an elevation in which of the following?

Serum amylase
Alkaline phosphatase
Mean corpuscular hemoglobin concentration (MCHC)
Indirect bilirubin
Alkaline phosphotase
Obstructive biliary disease causes a significant elevation in alkaline phosphotase. Obstruction in the biliary tract causes an elevation in direct bilirubin, not indirect bilirubin
In caring for the client 4 days post-cholecystectomy, the nurse notices that the drainage from the T-tube is 600 mL, in 24 hours. Which is the appropriate action by the nurse?

Clamp the tube q 2hours for 30 minutes
Place the patient in a supine position
Assess drainage characteristics and notify the physician
Encourage an increased fluid intake
Assess drainage characteristics and notify the physician
The T-tube may drain 500 mL in the first 24 hours and decreases steadily thereafter. If there is excessive drainage, the nurse should further assess the drainage to be able to describe it accurately and notify the physician immediately.
The post-cholecystectomy client asks the nurse when the T-tube will be removed. Which of the following responses by the nurse would be appropriate?
“When your stool returns to a normal brown color, the tube can be removed.”
“The tube will be removed at the same time as your staples.”
“When the tube stops draining, it will be removed.”
“The tube is usually removed the day after surgery.”
A When T tube drainage declines and stool returns to normal brown color, the tube can be clamped 1-2 hours before and after meals in preparation for tube removal. If the client tolerates clamping, the tube can be removed.
Which of the following assessments made by the nurse could indicate the development of portal hypertension in a client with cirrhosis?

Hemorrhoids
Bleeding gums
Muscle wasting
Hypothermia
A. Hemorrhoids Obstruction to portal blood flow causes a rise in portal venous pressure resulting in splenomegaly, ascites, and dilation of collateral venous channels predominantly in the paraumbilical and hemorrhoidal veins and others. Bleeding gums would indicate insufficient vitamin K production in the liver. Muscle wasting commonly accompanies the poor nutritional intake commonly seen in clients with cirrhosis.
The nurse is caring for a client who has ascites, and the health care provider prescribes spirolactone (Aldactone). The client asks why this drug is being used. Which is the best response by the nurse?

“This drug will help increase the level of protein in your blood.”
“The drug will cause an increase in the amount of hormone aldosterone your body produces.”
“This medication is a diuretic but does not make the kidneys excrete potassium.”
“This will help you excrete larger amounts of ammonia.”
Spirolactone is used in clients with ascites that show no improvement with bedrest and fluid restriction. It inhibits sodium reabsorption in the distal tubule and promotes potassium retention by inhibiting aldosterone.
When caring for a client who has cirrhosis, the nurse notices flapping tremors of the wrist and fingers. How should the nurse chart this finding?

“Trousseau’s sign noted.”
“Caput medusa noted.”
“Fector hepaticus noted.”
“Asterixis noted.”
D D Asterixis, also called liver flap, is the flapping tremor of the hands when the arms are extended. A reflects hypocalcemia. B refers to spiderlike abdominal veins that are also commonly found in clients with cirrhosis who have portal hypertension as a complication. Option C is a specific odor noted in liver failure.
Diagnostic test for TSH
T# an T4 levels
what is a symptom of hypertyroidsm
constipation
bed rest and antiviral meds would be ordered for the person with Hep __
A
a disease associated with hyperthyroidims
graves disease
OA, oral antidiabetics that cause decrease glucose production from the liver
biguanides
when checking a newborn from a diabetic mother 2-4 hours after birth you'd look for what
signs of hypoglycemia
you would test for ketone in the urine when BGL are
> 240 mg/dL when tested two times
meds that decrease hepatic glucose output in liver
Biguanides: glucophage
Thiaxolidinediones- actos and avandia
meds that decrease glucose absorption in intestines
alpah glusodieuse inhibitors
prcose and glset
meds that increase peripheral glucose uptake in muscles
Thiaxolidinediones: actos and avandia,
Biguanides-glucophage
meds that increase insulin secretion from pancreas
sulfonylurea: flipizide, glyburide, limepride
meglitinides: nateglinide, praglinide
men who drink 4 or more glassse or beer wine or other drinks each day are high risk for
cirrhosis
bed rest and antiviral meds would be ordered for the person with Hep __
A
a disease associated with hyperthyroidims
graves disease
OA, oral antidiabetics that cause decrease glucose production from the liver
biguanides
when checking a newborn from a diabetic mother 2-4 hours after birth you'd look for what
signs of hypoglycemia
you would test for ketone in the urine when BGL are
> 240 mg/dL when tested two times
meds that decrease hepatic glucose output in liver
Biguanides: glucophage
Thiaxolidinediones- actos and avandia
meds that decrease glucose absorption in intestines
alpah glusodieuse inhibitors
prcose and glset
meds that increase peripheral glucose uptake in muscles
Thiaxolidinediones: actos and avandia,
Biguanides-glucophage
meds that increase insulin secretion from pancreas
sulfonylurea: flipizide, glyburide, limepride
meglitinides: nateglinide, praglinide
men who drink 4 or more glassse or beer wine or other drinks each day are high risk for
cirrhosis
hepatocellular jaundice is cause by an obstruction in the bile duct, T or F
F, it is not in the liver...hepatocellular is
Vit K is needed for sythesis of
prothrombin, PT time
a common symptom of ascitesis
increase ab girth
esophogeal varies result from what
portal hypertension, big veins
leading cause of acute liver failure is
tylenol
high levels of serum ammonia can cause
hepatic encephalopathy
Alk Pho and a glutamyltacaisferase are markers for
cholestasis
very long acting insulin
lantus, glargine 1 hour onset duration 24 hours
metoprolo (toperol XL and Lopressor are what class and used for what
beta blockers HTN
Type 2 diabetes is more prevalant that one T or F
true
Can an insulin dependent pt have the physiological decrease in ciruclating insulin that normally occurs with exercise?
NO
Lassic clinical maifestations of all types of diabetes include the three P's what are they
polydypsia (thirst)
polypahgia,
polyuria
what is the term used to describe how much a given food increases the blood glucose level compared with an equivalent amount of glucose
glycemic index
a blood test that relfects average blood glucose levels over a period of 2-3 months
Clycolicated HG aclhg
what is the most common risk of insulin pump therapy
ketoacidosis
what are 3 major acute complications of diabetes related to short term imbalances in blood glucose levels
hypoglycemia, DKA, hyper....
The DCC, CTT study
tight control of glucose to prevent long term complications like renal failure etc.
Kussamal def
rapid deep breathing
when glucsoe levels approach 250mg/dL in ketoacidosis what do you do
5% dextrose
Short acting insulins, 2
Humulin R, Novloin R
generic: Reuglar Human Insulin injection,
recombinant DNA origin
Humulin R and Novoling R, are what type of insulin and what is onset, peak and duration
Short Acting
Onset, 30min-1hr,
peak 2-3 hours,
duration 4-6 hours
Rapid Acting Insulin (2)
Humalog-insulin lispro injection and Novalog- asvarte
Humalog-insulin lispro injection and Novalog- asvarte are what type of insulin and give onset, peak and duration
rapid acting
Onset: 5-15 min
Peak: 1 hour
Duration: 2-4
Intermediate Acting Insulin (2)
Humulin L-lente human insulin
Humulin N- NPH human insulin
Nolvolin N-NPH human insulin
Humulin L-lente human insulin
Humulin N- NPH human insulin
Nolvolin N-NPH human insulin are what kind of insulin and give onset peak and duration
Intermediate Acting
Onset: 2-4 hours
Peak: 4-12
Duration: 16-20
Long acting insulin (1)
onset peak and duration
Humulin U-ultralente human insuling,
onset 6-8 hours,
peak 12-16
duration: 20-30 hours
very long acting insulin (1)
onset, peak and duration
Lantus- insulin glargine
CAN NOT MIX w/ other insulins
onset 1 hour
peak: no peak
duration 24 hours
type one or two?
thirst up
bed wetting
rapid onset
type one
also weight decrease
type one or two?
eye problems
slow onset
type two also increased weight
Dx of DM type one or two done by FBG would be what
FBG >126 mg/dL confirmed by test on another day
dx of DM type I or II
3 tests with numbers
FBG > 126 mg/dl on 2 seperate days

casual or random glucose > 200mg/dl + symptoms

glucose tolerance test > 200mg/dL