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103 Cards in this Set
- Front
- Back
It involves the insertion of DNA from one organism into another or modification of an organisms DNA in order to achieve a desired trait. |
Genetically modified organism. |
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What is the difference of selective breeding from genetic modification? |
Selective breathing is slow imprecise and naturally occur in the organism on the other hand genetic modification is very fast more precise and has the ability to introduce genes into organisms that would not naturally occur. |
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Artificial selection has influenced the genetic makeup of livestock and crops for thousands of years.True or false. |
True |
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Proponents of GM crops say GM foods are not safe. T or f |
False |
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What does critics of GM foods say? |
The traditional breeding use genes from the same species. Selective breeding deals with whole organisms not just genes. In traditional breeding genes come together on their own. |
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Changes organisms through selection. |
Traditional Breeding. |
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It is more like the process of mutation |
Genetic Engineering. |
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It is the material application of biological science to create products derived from organisms. |
Biotechnology. |
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It is an organism that contains DNA from another species. |
Transgenic organism. |
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The genes that have moved between organisms. |
Transgenes |
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Give 5 examples of GMO in medicine. |
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Example of GMO in biofuel. |
Algenol Biofuels and Rapeseed |
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Gmo in bio remediation. |
poplar trees removed groundwater contaminants. Enviropig (frankenswine).Able to digest and process phosphate |
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Gmo in pesticides. |
Kills caterpillars but not poisonous to humans. |
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GMO in manufacturing. |
Produces silk in milk to make biosteel |
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Some examples of genetically modified foods |
Bt crops. Roundup ready crops. Ice minus strawberries. Golden rice. Startlink corn. AquAdvantage salmon. |
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Golden rice is genetically modified by inserting a gene from maize and a gene from bacteria found in soil which allows the plant to biosynthesized ______ in rice. |
Beta carotene |
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Give examples of common GM foods. |
Corn Canola Potatoes Tomatoes Squash Soybeans Flax Cottonseed oil and Sugar beets. |
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It is the most covered GM foods that comprises 57.5%. |
Soybeans. |
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least type of Gm CROPS WITH ONLY 4.7 % |
Canola |
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experts say ___ to ___ % of processed foods on US grocery shelves have genetically modified ingredients. |
60 to 70 |
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nation that has the highest GM crops |
United States |
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percentage of unexplained cause of infertility |
18% |
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causes of infertiity in women |
ovulation disorders tube/uterus blockage cervix endometriosis |
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cause of infertility in men |
sperm count and defects erctile or ejaculation deficiency |
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environmental cause is called |
extrinsic |
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ovulatory failure can be: |
polycystic ovarian syndrome resistant ovarian syndrome gonadal dysgenesis |
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immpaired gamete / zygote transport can be: |
inflammatory disease endometriosis |
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an effect of low progesterone levels |
implantation defects |
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result of chromosome abnormality |
spontaneous abortion |
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condition in which one or both of the testes fail to descend from the abdomen into the scrotum. |
cryptorchidism |
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example of chromosome disorders |
gonadal dysgenesis |
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gonadotropin deficiency results in |
low sperm count and sperm of poor quality |
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female infertility tests for ovulation |
basal body temperature ovulation kit hormone tests (steroids) |
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femal infertility tests for post ovulatory block |
laparoscopy hysterosalpingogram post coital/cervial mucuous and sperm sperm antibodies endometrial biopsy |
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this procedure can find adhesions, structural abnormality |
laparoscopy |
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this procedure can look into block tubes |
hysterosalpingoram |
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how many sperms are there in 1 ml of semen |
50 million sperm cells |
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normal semen count per ejaculation |
2 to 5 ml |
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infertility for men |
>20 million sperm per ml >50% motile >30% structurally normal |
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male infertuuliy test procedure |
testicular biopsy |
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example of older low tech treatments |
drug tretaement for ovulation block itrauterine insemination tubal surgery |
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high tech assisted reproductio technologies |
IVF GIFT ZIFT Intracytoplasmic sperm injection |
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IVF |
Invitro fertilization. |
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GIFT |
Gamete Intrafallopian tube transfer |
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ZIFT |
Zygote intrafallopian tube transfer |
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On this procedure, the eggs and sperm are collected as with IVF, but then injected directly into the woman's fallopian tubes so fertilization occurs inside the body |
Gift |
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It is used when male has low sperm counts or sperm with poor mortility or if a couple has moral objections to IVF |
GIFT |
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It combines aspect sof both IVF and GIFT. |
ZIFT |
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On this procedure fertilization takes place outside the uterus and placed into the fallopian tubes |
ZIFT |
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On a ZIFT procedure, eggs are collected and fertilized by the partner's sperm in the _________ |
Laboratory |
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The name of the first test tube baby |
Louise Joy Brown |
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Basic steps in IVF |
Ovary stimulation Egg retrieval Sperm retrieval Fertilization Embryo transfer Progesterone |
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Drugs used for ovary stimulation |
-Clomiphene -Human menopausal gonadotropins-Follicle stimulating hormone -Gonadotropin hormone-releasing hormone -Gonadotropin hormone-releasing hormone Agonist -Human chorionic gonadotropin |
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Clomiphene is a s anti estrogen that i also known as |
Clomid |
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FSH is also known as |
Metrodin |
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GnRH agonist is also known as |
Lupron |
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You could take clomid, performances, HCG shot, and progesterone in a single cycle |
True |
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Why do you need to transfer more that one embryo |
-increase the pregnancy rate -leads to incrasd risk of multiple pregnancies -test embryos before transfer |
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GIFT is executed through a surgical incisions |
No. Ultrasound guide |
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This is the removal or change in the genetic material in the cells of a patient |
Gene Therapy |
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Help make functioning proteins despite the presence o of a faulty gene |
Gene therapy |
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5 types of gene therapy |
-gene addition -gene correction -gene silencing -reprogramming -cell elimination |
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On gene therapy a working copy of a gene is transferred into the target cell using a _______ |
Vector |
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Inserting a new copy of gene into the target cells |
Gene Addition |
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Modifying part of a gene using recently developed gene editing technology |
Gene correcction |
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Example of recently developed gene editing technology |
CRISPR/cas9 , TALEN, ZFN |
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Prevents the production of specific protein y targetinng mRNA |
Gene Silencing |
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Mrna |
Messenger Ribonucleic acid |
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Involves adding one or more genes to cells of a specific type |
Reprogramming |
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Used to destroy malignant tumour cells |
Cell elimination |
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Cancerous |
Malignant |
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It is the transfer of cells into patient with tthe goal of improving a diseasse |
Cell therapy |
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Exampl of a cell therapy |
CAR-T cell therapy |
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It is the introduction, removal, or change in genetic material-DNA |
Gene therapy |
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The patient's cell are reoved from the body |
Cell therapy |
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Its goal is to remov, disrupt, or correct faulty elements if dna within the gene |
Gene editing |
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6 types cell therapy |
-embryonic stem cells -induced pluripotent stem cells - nuclear transfer embryonic stem cells -hematopoietic stem cells -immune cell therapy -other stem cell therapy |
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Pluripoent stem cellsderived from embryos |
Embryonic stem cell |
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A differentiated adult ell such as skin cell is reprogrammed to return to pluripotent cell |
INduced pluripotent stem cells |
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Adult cells are called |
Somatic |
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Plurpotent cells are produced by trannsferring the nucleus from an adult cell obtained from the patient to an oocyte obtained from a donor |
Nuclear transfer embryonic stem cell |
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a single cell that can replicat itself or differentiate into many cell types |
Stem cell |
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The first mammal to have been successfully clned from an adult cell is a? |
Sheep |
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Consdiered to be the poster child of modern biotechnology |
Dolly the sheep |
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Give some exmaple of potential uses of adult stem cell |
Missing teeth Cirrhosis Arthritis Lung cancer Baldness Blindness Deafness |
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Multi potent blod stem cells that give rise to all types of blood cells |
Hematopoietic stem cells |
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Cells can be removed from the bod, isolated from a mixed cell population, modified and tehn expaned befoor return to the body |
Immune cell therapy |
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Example of Immune cell therapy |
CAR-T cell therapy |
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Other stem cell sources: |
Mesenchymal Neural Epithelial |
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It states the prohibition and restriction of the creation, importation promotion, marketing, an us of stem cell therapies from ebryonic, abored fetal, and genetically altered, animal, and plant stem cell |
Administrative order no. 2013-0012 |
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It is an undifferntiated dividing cell that gives rise to a daughter cell like itself and a daughte cell that becomes a specialized cell type. |
Stem cell |
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All stem cells can |
Self renew and differentiate |
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Three stem cell types |
Embryonic Tissue specific Induced pluripotent |
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Can form almost any cell type in the human body |
Embryonic |
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Multipotent: can form only limited types of cells |
Tissue specific |
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Engineered kby scientists to act like embryonic stem |
Induced pluripotent |
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Most promising type of stem cell for therapy |
Embryonic stem cell |
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What diseases do stem cells treat? |
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example of a tissue specific stem cell therapy |
Bone marrow transplant Trachea transplantation |
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Why do researchers stuudy embryonic stem cell?
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Challenges |
Differentiation of stem cells into mature, functional cells Potential for rtumor formation Immune rejection |
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Derived from skin r blood cells hat have bee reprogrammed back into an embryonic like pluripotent stat that enables teh dvelopment o an unlimited source of any typ of human cell needed foor therapeutic purposes |
Induced pluripotent stem cell |