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206 Cards in this Set

  • Front
  • Back
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Energy & mechanical work :


A. Lifting weights for a very short duration with high intensity


B. Running 400 m at a slightly longer duration with moderate intensity


C. Distance running for a long duration with low intensity

Back (Definition)

The energy stored in these substrate molecules is then chemically released in

Cells & stored in the form of a high-energy compound, Adenosine triphosphate ATP

Bioenergetics

The study of energy in the human body.

Energy metabolism

Energy is required to

Sustain life


Support exercise


Help recover from exercise

There are 3

What is the ultimate source of energy?

The sun.

Through photosynthesis, energy from the sun produces

Chemical energy & other compounds used to convert CO2 into organic chemicals (glucose).

Metabolism

All of the chemical reactions that occur in the body to maintain itself.

Metabolism is the process in which

Nutrients are required, transported, used, & disposed of by the body.

What are the main sources of chemical energy for most organisms?

Carbohydrates


Lipids (Fats)


Proteins

The energy from the oxidation of carbohydrates, fats, & proteins sustains

The biochemical reactions required for life.

Exercise metabolism

The examination of bioenergetics relating to do unique physiologic changes & demands placed on the body during exercise.

Substrates

The material/substance on which an enzyme acts.

Basic overview of energy metabolism :

Back (Definition)

Carbohydrates

Organic compounds of carbon, hydrogen, & oxygen.

What are some examples of carbohydrates?

Starches


Cellulose


Sugars

Carbohydrates

Organic compounds of carbon, hydrogen, & oxygen that are an important source of energy.

All carbohydrates are eventually broken down in

The body to glucose, a simple sugar.

Fat

A good source of energy that helps the body use some vitamins & keep the skin healthy.

One of the 3 main classes of foods.

Fat serves as

Energy storage for the body.

What are the two types of fat?

Saturated fat


Unsaturated fat

Triglycerides

The chemical/substrate form in which most fat exists in food/the body.

When calories are consumed but not immediately needed by cells or tissues they are

Converted into triglycerides & transported to fat cells where they are stored.

One of the benefits as bad as if your sources that most people have

Inexhaustible supply of fat, which can be broken down into triglycerides & used for energy during prolonged physical activity/exercise.

Protein

Amino acids linked by peptide bonds, consisting of carbon, hydrogen, nitrogen, oxygen, & usually sulfur, that have several essential biologic compounds.

When does protein become a significant source of fuel?

Starvation.

During a negative energy balance (low calorie diet), amino acids are used to

Assist in energy production.

Gluconeogenesis

The formation of glucose from non-carbohydrate sources, (amino acids).

Carbohydrates provide the body with a source of

Fuel & energy required for all daily activities, including exercise..

Adenosine triphosphate

Energy storage and transfer unit within the cells of the body.

One of the Primary sources of immediate energy.

When the chemical bonds that hold ATP together are broken, energy is

Released for cellular work (performing muscle contraction), leaving behind Adenosine diphosphate (ADP).

What do our bodies need a constant supply of in order to function properly?

Energy.

A lack of carbohydrates in the diet can cause what?

Fatigue


Poor mental function


Lack of endurance & stamina

There are 3

Glucose

A simple sugar that serves as the body’s main source of fuel.

Glucose is manufactured by the body from

Carbohydrates


Protein


Fat

Glucose is absorbed & transported in the ___ where it circulates until it enters ___ & it’s either ___ or ___.

Blood


Cells


Used or stored as energy.

Glycogen

The complex carbohydrate molecule used to store carbohydrates in the liver & muscle cells.

When carbohydrate energy is needed, glycogen is

Converted into glucose for use by the muscle cells.

Glycogen is a string of glucose molecules that can rapidly be

Broken down into glucose & used for energy during periods of prolonged/intense exercise.

Adenosine triphosphate (ATP)

Energy storage and transfer unit within the cells of the body.

One of the Primary sources of immediate energy.

One of the functions of energy metabolism is the harness and the free energy to

Reattach a phosphate group to an ATP & restore ATP levels back to normal to perform.

Energy is used to form the

Myosin-actin cross-bridges that facilitate muscle contractions.

A bridge.

At the myosin-Actin cross-bridges there is an

Enzyme that separates a phosphate from the ATP, releasing energy.

Energy is needed to allow the cross bridge to

Ratchet the thin actin filament toward the center of the sarcomere.

Another ATP is needed to release the cross bridge so that it can

Flip back & grab the next actin active site & continue the contractile process.

How many ATPs are needed for 1 cycle of a cross-bridge?

2 ATPs.

When are the ATP is completely depleted, there is

No energy to break the connection between the cross bridges in actin active sites, the muscle goes into rigor.

Any form of exercise can be defined by 2 factors, what are they?

Intensity


Duration

Energy & mechanical work :


A. Lifting weights for a very short duration with high intensity


B. Running 400 m at a slightly longer duration with moderate intensity


C. Distance running for a long duration with low intensity

Back (Definition)

The human body does not technically make energy, but rather

Transfers energy from the sun through food to the cells to perform their specific cellular & mechanical functions.

One of the functions of energy metabolism is the harness and the free energy to

Reattach a phosphate group to an ATP & restore ATP levels back to normal to perform.

What percentage of the energy released from ATP is actually used for cellular work?

40%

Muscle contractions

What is done with the remainder of the energy released from ATP?

It is released as heat.

Energy is used to form the

Myosin-actin cross-bridges that facilitate muscle contractions.

A bridge.

At the myosin-Actin cross-bridges there is an

Enzyme that separates a phosphate from the ATP, releasing energy.

Energy is needed to allow the cross bridge to

Ratchet the thin actin filament toward the center of the sarcomere.

Another ATP is needed to release the cross bridge so that it can

Flip back & grab the next actin active site & continue the contractile process.

How many ATPs are needed for 1 cycle of a cross-bridge?

2 ATPs.

When are the ATP is completely depleted, there is

No energy to break the connection between the cross bridges in actin active sites, the muscle goes into rigor.

Any form of exercise can be defined by 2 factors, what are they?

Intensity


Duration

Energy & mechanical work :


A. Lifting weights for a very short duration with high intensity


B. Running 400 m at a slightly longer duration with moderate intensity


C. Distance running for a long duration with low intensity

Back (Definition)

The human body does not technically make energy, but rather

Transfers energy from the sun through food to the cells to perform their specific cellular & mechanical functions.

One of the functions of energy metabolism is the harness and the free energy to

Reattach a phosphate group to an ATP & restore ATP levels back to normal to perform.

What percentage of the energy released from ATP is actually used for cellular work?

40%

Muscle contractions

What is done with the remainder of the energy released from ATP?

It is released as heat.

What happens when the enzyme ATP combines with an ATP molecule?

It splits the last phosphate group away, releasing a large amount of free energy.

How much free energy is released when the enzyme ATP combines with an ATP molecule?

~ 7.3 kcal per unit of ATP

Once the phosphate group has been split off, what remains is

ADP & an inorganic phosphate molecule (PI)

APT↔️ADP + Pi + energy release

Back (Definition)

Energy is used to form the

Myosin-actin cross-bridges that facilitate muscle contractions.

A bridge.

At the myosin-Actin cross-bridges there is an

Enzyme that separates a phosphate from the ATP, releasing energy.

Energy is needed to allow the cross bridge to

Ratchet the thin actin filament toward the center of the sarcomere.

Another ATP is needed to release the cross bridge so that it can

Flip back & grab the next actin active site & continue the contractile process.

How many ATPs are needed for 1 cycle of a cross-bridge?

2 ATPs.

When are the ATP is completely depleted, there is

No energy to break the connection between the cross bridges in actin active sites, the muscle goes into rigor.

Any form of exercise can be defined by 2 factors, what are they?

Intensity


Duration

Energy & mechanical work :


A. Lifting weights for a very short duration with high intensity


B. Running 400 m at a slightly longer duration with moderate intensity


C. Distance running for a long duration with low intensity

Back (Definition)

APT↔️ADP + Pi + energy release

Back (Definition)

Once the phosphate group has been split off, what remains is

ADP & an inorganic phosphate molecule (Pi)

Once an ATP has been used it must be

Replenished again before it can provide energy again.

By transferring a phosphate (and it’s accompanying energy) from another high energy molecule called ___ to an ADP molecule, ___.

Phosphocreatine (CP or PC)


Enough energy can be produced to facilitate 1 cross-bridge cycle.

What are ATP and PC/CP called?

Phosphagens, this is sometimes referred to as the phosphagen system.

The ATP-PC system occurs without the presence of what?

Oxygen (anaerobic).

The ATP-PC system provides energy for primarily

High intensity, short duration bouts of exercise/activity.

The ATP-PC system can be seen and what types of training?

Power and strength forms of training :


Heavy loads/few repetitions


Short sprinting events

During an all out sprint, the combination of ATP & PC stores could supply energy to

All of the working muscles for only 10-15 secs before complete exhaustion was reached.

The ATP-PC system is activated at the

Onset of activity, regardless of intensity, because of its ability to produce energy rapidly in comparison with other systems.

ATP-PC system :

Back (Definition)

Another anaerobic means of producing ATP is through the

Chemical breakdown of glucose, anaerobic glycolysis.

Before glucose or glycogen can generate energy, it must be converted to a

Compound called glucose-6-phosphate.

The process of glycolysis does not begin until

Either glucose or glycogen is broken down into glucose-6-phosphate.

The overall goal of glycolysis is to

Produce energy.

The conversion of glucose to glucose six phosphate actually

Uses up 1 ATP molecule, whereas with glycogen it does not.

Glucose or glycogen can be broken down to either

Pyruvic acid (aerobic glycolysis)


or


lactic acid (anaerobic glycolysis)

How many ATP are produced for each mole or unit of glucose?

2 ATP

How many ATP are produced for each unit of glycogen?

3 ATP

Although the glycolysis system can produce a significantly greater amount of energy then the ATP-PC system, how long does the energy last?

~30-50 secs

Hydrogen ions released during glycolysis & during the Krebs cycle combined with other enzymes & in the

3rd process of oxidation, providing energy for the oxidative phosphorylation of ADP to form ATP (electron transport chain).

Depending on some details, how much ATP is produced after the complete metabolism of a single glucose molecule?

Between 35 & 40 ATP.

That can only be metabolized

Aerobically.

What is the 1st step in oxidation of fat?

A process called B-oxidation.

B-oxidation

The breakdown of triglycerides into smaller subunits called free fatty acids (FFAs) to convert FFA into Acetyl CoA molecules, which then are available to enter the Krebs cycle, ultimately leading to the production of additional ATP.

The oxidative system :

Back (Definition)

Depending on what specific of kind fat is oxidized (ex:palmitic acid), how many ATP molecules are produced from 1 molecule?

129 ATP molecules

What type of oxidation produces more ATP per molecule compared with others?

Fat oxidation produces more ATP per molecule of fat compared to a molecule of carbohydrate.

Fat oxidation requires more

Oxygen to produce ATP.

Carbohydrates are the preferred fuel substrate for

The oxidative production of ATP.

The most fitness workouts will place a greater stress on this glycolysis system than the other systems because

A typical repetition range of 8-12 reps falls within the timeframe.

What are the in results of the aerobic metabolism of carbohydrates & fats?

Water & carbon dioxide, which are both easily eliminated (compared to lactic acid).

The aerobic breakdown of glucose & fat takes ___ than the anaerobic metabolism of ___ & far ___.

Much longer


Glucose


Longer than the ATP-PC cycle

Aerobic metabolism has the capability to produce energy, at least for exercise, for an

Indefinite period of time, because everyone has an ample supply of storage fat.

Energy during exercise :


X axis : exercise time at maximum capacity


Y axis : percentage of energy supplied by various fuel sources


Immediate energy systems : Very short duration (sprint) ATP-PC


Back (Definition)

As the duration of exercise increases out to (~ 2 mins), the primary source of energy comes from

Anaerobic metabolism of glucose (anaerobic glycolysis).

After several minutes of exercise, the oxidation of glucose in fat predominates as

The primary source of energy.

When glycogen stores are depleted, excess the intensity begins to

Slow as the primary energy supply turns from glycogen to fats.

After 90 minutes of exercise, the majority of

Muscle glycogen stores are depleted.

Through a combination of training & high carbohydrate intake, it is possible to store

Significantly greater quantities of glycogen, perhaps up to 50% more.

Greater quantities of glycogen allows athletes to

Exercise for longer periods before for taking or reaching a point of exhaustion.

The glycolysis system :

Back (Definition)

The bio energetics of exercise can be indirectly measured in a

Laboratory using various modes of exercise while measuring the concentrations of oxygen, carbon dioxide & volume of expired air.

What are some examples of the way bio energetics of exercise can be measured?

(treadmill, ergometer, rolling ergometer, cross country ski simulator, swimming flume)

When are Measurements made for the purpose of assessing exercise metabolism typically made?

During periods of steady-state.

Steady state exercise

Exercise performed at a constant pace (intensity).

Walking a brisk pace of 4 mph


15 minutes per mile

Substrates with the aid of oxygen to generate ATP.

Substrates with the aid of oxygen to generate ATP.

All 3 of the oxidative processes involved in the production of ATP involve

Oxygen & thus are referred to as aerobic processes.

The three oxidative or aerobic systems include :

Back (Definition)

The presence of oxygen in glycolysis only determines the fate of

The end product,


In the presence of oxygen, pyruvic acid is converted into an important molecule the metabolism called acetyl coenzyme A (acetyl CoA).

What is the end product of Pyruvic acid without oxygen?

The end product is lactic acid.

Acetyl CoA is an important molecule because it contributes

Substrates for use in the 2nd process of oxidative production of ATP, the Krebs cycle.

In the complete oxidation of Acetyl CoA how many units of ATP is created? What else is created?

2 units of ATP


Hydrogen & carbon dioxide

Although the glycolysis system can produce a significantly greater amount of energy then the ATP-PC system, how long does the energy last?

~30-50 secs

Hydrogen ions released during glycolysis & during the Krebs cycle combined with other enzymes & in the

3rd process of oxidation, providing energy for the oxidative phosphorylation of ADP to form ATP (electron transport chain).

The glycolysis system :

Back (Definition)

That can only be metabolized

Aerobically.

What is the 1st step in oxidation of fat?

A process called B-oxidation.

The three oxidative or aerobic systems include :

Back (Definition)

The oxidative system :

Back (Definition)

Depending on what specific of kind fat is oxidized (ex:palmitic acid), how many ATP molecules are produced from 1 molecule?

129 ATP molecules

What type of oxidation produces more ATP per molecule compared with others?

Fat oxidation produces more ATP per molecule of fat compared to a molecule of carbohydrate.

Fat oxidation requires more

Oxygen to produce ATP.

Carbohydrates are the preferred fuel substrate for

The oxidative production of ATP.

The most fitness workouts will place a greater stress on this glycolysis system than the other systems because

A typical repetition range of 8-12 reps falls within the timeframe.

What are the in results of the aerobic metabolism of carbohydrates & fats?

Water & carbon dioxide, which are both easily eliminated (compared to lactic acid).

The aerobic breakdown of glucose & fat takes ___ than the anaerobic metabolism of ___ & far ___.

Much longer


Glucose


Longer than the ATP-PC cycle

Aerobic metabolism has the capability to produce energy, at least for exercise, for an

Indefinite period of time, because everyone has an ample supply of storage fat.

The oxidative system :

Back (Definition)

As the duration of exercise increases out to (~ 2 mins), the primary source of energy comes from

Anaerobic metabolism of glucose (anaerobic glycolysis).

After several minutes of exercise, the oxidation of glucose in fat predominates as

The primary source of energy.

When glycogen stores are depleted, excess the intensity begins to

Slow as the primary energy supply turns from glycogen to fats.

After 90 minutes of exercise, the majority of

Muscle glycogen stores are depleted.

Through a combination of training & high carbohydrate intake, it is possible to store

Significantly greater quantities of glycogen, perhaps up to 50% more.

Greater quantities of glycogen allows athletes to

Exercise for longer periods before for taking or reaching a point of exhaustion.

The glycolysis system :

Back (Definition)

Energy during exercise :


X axis : exercise time at maximum capacity


Y axis : percentage of energy supplied by various fuel sources


Immediate energy systems : Very short duration (sprint) ATP-PC


Back (Definition)

What are some examples of the way bio energetics of exercise can be measured?

(treadmill, ergometer, rolling ergometer, cross country ski simulator, swimming flume)

When are Measurements made for the purpose of assessing exercise metabolism typically made?

During periods of steady-state.

Steady state exercise

Exercise performed at a constant pace (intensity).

Walking a brisk pace of 4 mph


15 minutes per mile

Substrates with the aid of oxygen to generate ATP.

Substrates with the aid of oxygen to generate ATP.

All 3 of the oxidative processes involved in the production of ATP involve

Oxygen & thus are referred to as aerobic processes.

The three oxidative or aerobic systems include :

Back (Definition)

The presence of oxygen in glycolysis only determines the fate of

The end product,


In the presence of oxygen, pyruvic acid is converted into an important molecule the metabolism called acetyl coenzyme A (acetyl CoA).

What is the end product of Pyruvic acid without oxygen?

The end product is lactic acid.

Acetyl CoA is an important molecule because it contributes

Substrates for use in the 2nd process of oxidative production of ATP, the Krebs cycle.

In the complete oxidation of Acetyl CoA how many units of ATP is created? What else is created?

2 units of ATP


Hydrogen & carbon dioxide

When considering steady-state exercise, and assumption Hass to be need that at the outset,

The energy required to walk on a treadmill at this pace this the same for the first few steps as it is for the last few steps.

While standing over the treadmill belt, there was a low energy requirement that

Rises immediately in a square with response when walking begins.

Once walking begins it stays

Constant for the duration of the walk.

Declines


Immediately on stepping off the treadmill.

Declines


Immediately on stepping off the treadmill.

The oxygen consumption of supine (lying down) rest is

Less than seated rest, which is less than standing at rest.

The simple anticipation of exercise

Raises the resting oxygen use.

After exercise the oxygen consumption stays

Elevated for a short period before starting a rapid decline.

Once the oxygen consumption starts to rapidly decline

A slower decline comes before finally returning to baseline.

If the caloric requirement exceeds the body’s ability to deliver energy aerobically, the body will

Make up the difference anaerobically, regardless of when this occurs during exercise.

Why does the body prefer aerobic or oxidative metabolism?

Because carbon dioxide & oxygen are more easily eliminated.

At the start of exercise what energy source does the body rely on?

The ATP-PC cycle


Anaerobic metabolism of glucose

Respiratory quotient (RQ)

The amount of CO2 expired


______________________________


the amount of CO2 consumed



Measured at rest / steady-state of exercise using a metabolic analyzer

What can be determined when VO2 & VCO2 are measured & the RQ calculated during steady state exercise?

The relative contribution of fats & carbohydrates as fuel sources.

During steady-state exercise, an RQ of 1.0 indicates what?

Carbohydrates are supplying 100% of the fuel.

During steady-state exercise an RQ of 0.7 indicates what?

Fats are supplying 100% of the fuel for metabolism.

Any RQ between 0.7 & 1.0 indicates what?

A mixture of carbohydrates & fats are feeling metabolism.

Oxygen consumption curve


Total energy needed

Oxygen consumption curve


Total energy needed

During exercise the rate of aerobic ATP production gradually

Increases, and less and less energy is derived from anaerobic sources.

Once the plateau has been reached, the energy demands of the exercise are

Being met by aerobic production of energy.

Excess postexercise oxygen consumption (EPOC)

The state in which the body‘s metabolism is elevated after exercise.

Once 80 PMPC levels have been restored and other physiologic processes have returned to normal, oxygen consumption will

Have returned close to the baseline, and immediate recovery will be mostly complete.

The recovery of the ATP-PC cycle is complete after how long?

~90secs

If the prior bouts of high intensity work is quite short, meaning it was probably fueled by ATPPC, the recovery period is

Correspondingly brief

If the period of high-intensity workouts longer,

The recovery period will take longer.

Recovery is what type of event?

An aerobic event to set ATP-PC concentrations back toward normal & the aerobic elimination of lactic acid.

At the start of exercise what energy source does the body rely on?

The ATP-PC cycle


Anaerobic metabolism of glucose

Respiratory quotient (RQ)

The amount of CO2 expired


______________________________


the amount of CO2 consumed



Measured at rest / steady-state of exercise using a metabolic analyzer

What can be determined when VO2 & VCO2 are measured & the RQ calculated during steady state exercise?

The relative contribution of fats & carbohydrates as fuel sources.

During steady-state exercise, an RQ of 1.0 indicates what?

Carbohydrates are supplying 100% of the fuel.

During steady-state exercise an RQ of 0.7 indicates what?

Fats are supplying 100% of the fuel for metabolism.

Any RQ between 0.7 & 1.0 indicates what?

A mixture of carbohydrates & fats are feeling metabolism.

RQ and percentage of calories from fats & carbohydrates :

Back (Definition)

A full 20 minutes of walking at 3.0 mph may result in in an RQ of 0.80 expends how many calories?

64 cal metabolism of fat


32 cal metabolism of carbohydrates

Hey for 20 minutes of walking at 6 mph requires more carbohydrates, so in our queue of 0.86, how many calories are expended?

104 cal from carbohydrates


90 cal from fat

Oxygen consumption curve


Total energy needed

Oxygen consumption curve


Total energy needed

During exercise the rate of aerobic ATP production gradually

Increases, and less and less energy is derived from anaerobic sources.

Once the plateau has been reached, the energy demands of the exercise are

Being met by aerobic production of energy.

Excess postexercise oxygen consumption (EPOC)

The state in which the body‘s metabolism is elevated after exercise.

Once 80 PMPC levels have been restored and other physiologic processes have returned to normal, oxygen consumption will

Have returned close to the baseline, and immediate recovery will be mostly complete.

The recovery of the ATP-PC cycle is complete after how long?

~90secs

RQ and percentage of calories from fats & carbohydrates :

Back (Definition)

If the period of high-intensity workouts longer,

The recovery period will take longer.

Recovery is what type of event?

An aerobic event to set ATP-PC concentrations back toward normal & the aerobic elimination of lactic acid.