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29 Cards in this Set
- Front
- Back
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how long can shistosomiasis last?
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up to 20-30 years
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What stage of shistosomiasis causes problems in the body?
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the eggs getting trapped in tissues
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How do humans spread shistosomiasis?
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fecal oral route involving waterways
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how to male and female shistosomes live together?
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one lives in a pouch of the other
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what is the infective stage of shistosomiasis?
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cercaria* penetrate the skin
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Where do shistosome worms typically migrate to?
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heart lungs liver and urinary bladder
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What species of shistosomiasis lives in the bladder?
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haemotbium
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What species of shistosomiasis infects the liver and intestine?
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mansoni
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What species of shistosomiasis attacks the brain and heart?
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japonicum
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What are the sings of the migratory phase of shistosomiasis?
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allergic reactions on the skin to cercarial entry
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What causes Katayama syndrome?
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this appears 14-84 days after exposure to shistosomiasis.
the syndrome is due to migration of shistosomulas and egg deposition |
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what is the presentation of Katayama syndrome?
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nocturnal fever, cough, myalgia, headache, abdominal tenderness
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how does shistosomiasis actually damage organs?
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the eggs cause granuloma formation, which leads to organ failure
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who usually gets katayama syndrome?
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people who are non-immune to shistosomiasis- and have had no previous exposure to the disease
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What causes the chronic phase of shistosomiasis?
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fibrotic response to eggs in tissues, causing loss of function
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What are the signs of chronic shistosomiasis with japonicum/mansori?
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mild bloody diarrhea
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What are the signs of chronic shistosomiasis with haematobium?
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bladder cancer, pain on urination with bloody urine
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what type of chronic bacterial infection can occur with shistosomiasis?
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salmonella
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how do shistosomes prevent host responses to the worms?
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the worms coat themselves with host antigens- so body never notices them
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what local factor causes egg production in shistosomiasis?
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TNF
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what local factor causes worm growth in shistosomiasis?
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IL-7
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How do you diagnose shistosomiasis?
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geographic
eggs in feces or urine (depends by species) |
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How does the number of eggs passed out of the body change over time in shistosomiasis?
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as the infection becomes chronic there are fewer eggs
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what is the shape of shistosomiasis japonicum?
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perfectly round, and found in the feces
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What is the shape of shistosomiasis mansoni?
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oval, with a small tail, found in feces
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where is swimmers itch common?
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in michigan
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what causes swimmers itch?
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this is due to cercariae of various species of avian shistosomes
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how long does it take swimmers itch to erupt?
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about 10-15 hours
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How long does it take vesicles to form with swimmers itch?
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about 2-3 days
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