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38 Cards in this Set

  • Front
  • Back

excretory system

serves many functions, including the regulation of blood pressure, blood osmolarity, acid-base balance and removal of nitrogenous wastes

kidney

produces urine, which dumps into the ureter at the renal pelvis; contains a cortex and a medulla; each one has a hilum, which contains a renal artery, renal vein and ureter; contains a portal system with two capillary beds in series

bladder

where urine is collected until it is excreted

urethra

what urine is excreted through

afferent arterioles

blood from the renal artery flows into these; these form glomeruli in Bowman's capsule (the first capillary bed of the kidney)

efferent arteriole

blood flows through this to the vasa recta, which surround the nephron (the second capillary bed of the kidney), before leaving the kidney through the renal vein

detrusor muscle

muscular lining of the bladder; under parasympathetic control; also has two muscular sphincters (internal urethral sphincter and external urethral sphincter)

internal urethral sphincter

consists of smooth muscle and is under involuntary (parasympathetic) control

external urethral sphincter

consists of skeletal muscle and is under voluntary control

kidney participates in solute movement through these three processes

filtration, secretion, and reabsorption

filtration

the movement of solutes from blood to filtrate at Bowman's capsule; the direction and rate of filtration is determined by Starling forces, which account for the hydrostatic and oncotic pressure differentials between the glomerulus and Bowman's space

secretion

the movement of solutes from blood to filtrate anywhere other than Bowman's capsule

reabsorption

movement of solutes from filtrate to blood

proximal convoluted tubule (PCT)

segment of the nephron; site of bulk reabsorption of glucose, amino acids, soluble vitamins, salts and water; also site of secretion for hydrogen ions, potassium ions, ammonia and urea

descending limb of the loop of Henle

segment of the nephron; permeable to water but not salt; therefore, as the filtrate moves into the more osmotically concentrated renal medulla, water is reabsorbed from the filtrate; the vasa recta and nephron flow in opposite directions, creating a countercurrent multiplier system that allows maximal reabsorption of water

ascending limb of the loop of Henle

segment of the nephron; permeable to salt but not water; therefore, salt is reabsorbed both passively and actively; the diluting segment is in the outer medulla; because salt is actively reabsorbed in this site, the filtrate actually becomes hypotonic compared to the blood

distal convoluted tubule (DCT)

segment of the nephron; responsive to aldosterone and is a site of salt reabsorption and waste product excretion, like the PCT

collecting duct

segment of the nephron; responsive to both aldosterone and antidiuretic hormone and has variable permeability, which allows reabsorption of the right amount of water depending on the body's needs

aldosterone

a steroid hormone regulated by the renin-angiotensin-aldosterone system that increases sodium reabsorption in the distal convoluted tubule and collecting duct, thereby increasing water reabsorption; the results in an increased blood volume (and pressure), but no change in blood osmolarity

antidiuretic hormone (ADH or vasopressin)

a peptide hormone synthesized by the hypothalamus and released by the posterior pituitary; its release is stimulated not only by low blood volume but also by high blood osmolarity; it increases the permeability of the collecting duct to water, increasing water reabsorption; this results in an increased blood volume (and pressure) and a decreased blood osmolarity

selective reabsorption or secretion of bicarbonate or hydrogen ions

how the kidney can regulate pH

three major layers of the skin

epidermis (top)


dermis


hypodermis (subcutaneous layer)

five layers of the epidermis

stratum corneum (top)


stratum lucidum


stratum granulosum


stratum spinosum


stratum basale

stratum basale

contains stem cells that proliferate to form keratinocytes

keratinocyte nuclei

lost in the stratum granulosum and many thin layers form in the stratum corneum

melanocytes

produce melanin

melanin

protects the skin from DNA damage caused by ultraviolet radiation; it is passed to keratinocytes

Langerhans cells

special macrophages that serve as antigen-presenting cells in the skin

two layers of the dermis

papillary layer (top)


reticular layer

Merkel cells

sensory cells located in the dermis; respond to deep pressure and texture

free nerve endings

sensory cells located in the dermis; respond to pain

Meissner's corpuscles

sensory cells located in the dermis; respond to light touch

Ruffini endings

sensory cells located in the dermis; respond to stretching

Pacinian corpuscles

sensory cells located in the dermis; respond to deep pressure and vibrations

postganglioninc cholinergic sympathetic neurons

innervate sweat glands

vasodilation

cooling mechanism

piloerection

warming mechanism in which arrector pili muscles contract causing hairs to stand on end (trapping a layer of warmed air around the skin)

vasoconstriction

another warming mechanism