Histopath

Front 1

Immunity

Back 1

The ability to resist infection and diseases.

Front 2

Immediate hypersensitivity (type 1)

Antibody mediated hypersensitivity (type 2)

Immune complex-mediated hypersensitivity (type 3)

T cell mediated hypersensitivity (type 4)

Back 2

What are the 4 types of hypersensitivity

Front 3

Degranulation

Back 3

It results in histamine release, which increases vascular permeability.

Front 4

Hypersensitivity reactions

Back 4

Adverse reactions caused by immune mechanisms are termed?

Front 5

Platelet aggregation

Back 5

It causes microthrombus formation and leads to the release of vasoactive amines from platelet-dense granules.

Front 6

Complement-fixing antibodies

Back 6

It react directly with antigens that are integral components of the target cell.

Front 7

Angiodema

Back 7

It is the acute edema of cutaneous or mucosal structures, most commonly involving the lips and eyelids.

Front 8

Anaphylactic shock

Back 8

Systemic anaphylaxis also known as?

Front 9

Serum sickness

Back 9

It is a systemic deposition of antigen-antibody complexes in multiple sites, especially the heart, joints, and kidneys.

Front 10

Distinguish self from non-self

Discriminate among potential invaders

Generate immune memory and amplification responses

Back 10

Immune responses are characterized by their capacity to:

Front 11

Immunodeficiency

Back 11

Term used to decribe if the immune system is deficient.

Front 12

Innate immunity

Adaptive immunity

Back 12

2 types of reactions of defense against microbes.

Front 13

Skin prick allergen testing

Back 13

It is a test used to know allergies

Front 14

Hypersensitivity diseases

Back 14

Immune responses that are capable of causing tissue injury and diseases are called?

Front 15

Epithelial barriers

Phagocytic leukocytes

Natural killer cell

Complement system

Back 15

The 4 major components or the innate immunity are:

Front 16

IgA

Back 16

What immunoglobulin is the major isotype in mucosal secretions?

Front 17

Dendritic cells

Back 17

Are major cells for displaying protein antigens to naive T cells to initiate immune response?

Front 18

Generative or primary organs

Peripheral or secondary organs

Back 18

The lymphoid tissue is divided into two organs namely:

Front 19

Immediate response phase

Back 19

This phase is characterized by vasodilation, vascular leakage and smooth muscle spasm, evident within 5-30mins after exposure to an antigen.

Front 20

Autoimmunity

Back 20

It is an immune reaction to self antigens

Front 21

Central tolerance

Back 21

This refers to the deletion of self-reactive T and B lymphocytes during their maturation in central lymphoid organs.

Front 22

Type Diabetes Mellitus

Back 22

It is strongly associated with HLA-DR3 or HLA-DR4

Front 23

Molecular mimicry

Back 23

What phenomenon shares a cross-reacting epitopes with self-antigens?

Front 24

Systemic Lupus Erythematosus

Back 24

It is a multisystem autoimmune disease of variable behavior. It affects the skin, kidneys, serosal membranes, joints, and heart.

Front 25

DNA

Histones

Nonhistone proteins bound to RNA

Antibodies to nuclear antigens

Back 25

What are the 4 categories that ANAs are grouped into?

Front 26

Indirect immunofluorescence

Back 26

What is the most common method to detect antinuclear antibodies?

Front 27

Monogeneous or diffuse

Back 27

_____ staining usually reflacts antibodies to chromatin, histones, and dsDNA

Front 28

True

Back 28

Kidney involvement is one of the most important clinical features of SLE with renal failure being the most common cause of death. (True or False)

Front 29

Class IV

Back 29

Diffuse proliferative glomerulonephritis (35% to 60%); most serious form belongs to what class?

Front 30

CNS disease

Back 30

It is often ascribed to vascular lesions causing ischemia or multifocal cerebral microinfarcts.

Front 31

Libman-Sacks endocarditis

Back 31

Myocarditis, in the form of a non specific mononuclear cell infiltrate, and valvular lesions, is called?

Front 32

Rhuematoid Arthritis

Back 32

It is a systemic, chronic inflammatory disease affecting many tissues but principally attacking the joints to produce a nonsuppurative proliferation synovitis that frequently progresses to destroy articular cartilage and underlying bone with resulting disabling arthritis.

Front 33

Serositis, Oral ulcers, Arthritis, and Photosensitivity

Back 33

In the criteria for SLE, we use SOAP-BRAIN-MD. What does SOAP stands for?

Front 34

Hemophilia

Back 34

In the criteria for SLE, which blood abnormality does not belong in the group?

Front 35

Systemic Lupus Erythematosus

Back 35

It is a fairly common disease. Like many autoimmune diseases, there is a strong (approximately 9:1) female preponderance.

Front 36

True

Back 36

The joint inflammation in RA is immunologically mediated.(true or false)

Front 37

Cardiogenic

Hypovolemic

Septic

Back 37

What are the general categories of shock?

Front 38

Nonprogressive stage

Progressive stage

Irreversible stage

Back 38

What are the stages of shock?

Front 39

Albumin

Back 39

What serum protein is most responsible for maintaining intravascular colloid osmotic pressure?

Front 40

GP IIb/IIIa

Back 40

A defect in what glycoprotein platelet membrane receptor causes Glanzmann thrombasthenia?

Front 41

Collage Exposure

Back 41

This activates the platelets and initiates the contact phase of coagulation.

Front 42

Vegetation

Back 42

Thrombi heart valves are called.