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285 Cards in this Set

  • Front
  • Back
ductless glands of the endocrine system include

pituitary, thyroid, adrenal, pancreatic, pineal and thymus and ovaries/testes

antagonistic

opposing

electrolyte

mineral salt that carries an electrical charge in a solution

glucagon

hormone produced by pancreatic alpha cells that stimulates the liver to change stored glycogen (a starch form of sugar) to glucose

glucose

simple sugar

insuline

hormone produced by the beta cells of the liver that allow the body cells to use glucose for energy or store it in the liver as glycogen

sympathomimetic

agent that mimics the effects of the sympathetic nervous system (epinephrine and NE)

pituitary gland (hypophysis)

master gland because it regulates many body activities


posterior lobe: ADH and oxytocin


and anterior lobe has ACTH, FSH, GH, LH, PRL, TSH

thyroid gland is the

largest gland of the endocrine system; separated by a lobe of tissue called an isthmus

ACTH

adrenocorticotropic hormone; promotes secretion of corticosteroids, especially cortisol

follicle stimulating hormone

promotes egg production in females; increases estrogen secretion


testes in males stimulate sperm production

growth hormone

regulate growth of bone, muscle, and other body tissues; increases use of fat for energy

luteinizing hormone

females: promotes ovulation, stimulates estrogen and progesterone production


males: promotes secretion of testosterone

prolactin

breast in conjunction with other hormones promotes lactation



thyroid stimulating hormone

stimulates secretion of thyroid hormones

antidiuretic hormone

kidney- increases water resorption (water returns to blood)

oxytocin

uterus: stimulates uterine contractions, initiates labor


breast: promotes milk secretion from the mammary glands

calcitonin

thyroid hormone: regulates calcium levels in the blood in conjunction with parathyroid hormone


decreases the resorption of calcium and phosphate from bones to blood

thyroxine and triiodothyronine

thyroid hormone; increases energy production from all food types; increases rate of protein synthesis

parathyroid hormone

bones: increases reabsorption of calcium and phosphate from bone to blood


kidneys: increases calcium absorption and phosphate excretion


small intestine: increases absorption of calcium and phosphate

mineralocorticoids

aldosterone: mainly through kidneys to maintain the balance of electrolytes in the body; conserve sodium and excrete potassium and conserves water

glucocorticoids

body cells- promote gluconeogenesis; regulate metabolism of carbs, proteins and fats, and help depress inflammatory and immune responses

sex hormones

females responsible for female libido and source of estrogen after menopause (otherwise insignificant effects)

epinephrine and NE

sympathetic nervous system target organs; hormone effects mimic sympathetic nervous system activation, increase metabolic rate and heart rate, and raise blood pressure by promoting vasoconstriction

pancreas is

endocrine and exocrine gland


glucagon secreted by alpha cells


insulin made by beta cells

glucagon

liver and blood- raises the blood glucose level by accelerating conversion of glycogen into glucose in the liver and other nutrients into glucose in the liver; and releasing glucose into the blood

insulin

tissue cells-lowers blood glucose level by accelerating glucose transport into cells and the use of that glucose for energy production (glucose to glycogen)

pineal gland--3rd ventricle of brain-

secretes melatonin (melatonin hi-ovulation is blocked and there is a delay in puberty)

adren/o


adrenal/o

adrenal glands

calc/o

calcium

crin/o

secrete

gluc/o


glyc/o


glycos/o

sugar, sweetness

home/o

same, alike

kal/i

potassium, an electrolyte

pancreat/o

pancreas

parathyroid/o

parathyroid glands

thym/o

thymus gland

thyr/o


thyroid/o

thyroid gland

toxic/o

poison

-crine

secrete

-dipsia

thirst

-gen

forming, producing, origin

-toxic

pertaining to poison

-uria

urine

eu-

good, normal

exo-

outside, outward

hyper-

excessive, above normal

hypo-

below, under

poly-

many, much

hypersecretion is generally treated by

surgery

endocrinology/ endocrinologist

treatment and management of endocrine disorders

pituitary disorders

usually hyper/hyposecretion of GH or ADH

GH disorder

lead to body size abnormalities

abnormal ADH

leads to excess fluid build up in the body and low blood sodium (hyponatremia)

cretinism

infant hypothyroidism disorder that can lead to mental retardation, impaired growth or low body temperatures and abnormal bone formation

myxedema

adult hypothyroidism- symptoms of edema, low blood levels of T3 and T4, weight gain, cold intolerance, fatigue, depression, muscle joint pain

graves disease

hyperthyroidism; elevated metabolic rate, weight loss, excessive perspiration, muscle weakness and emotional stability

exphthalmos

graves disease, eyes protrude outward because of edematous swelling in tissues behind them

thyroid gland enlarged

goiter

toxic goiter

occurs because of the excessive release of TSH from the anterior lobe; causes thyroid cells to enlarge and secrete extra amounts of hormones; drug therapy or surgery

hypoparathyroidism

insufficient production of PTH; caused by primary parathyroid dysfunction or elevated calcium levels;


primary effect is decreased blood calcium level; makes muscle twitches (tetany)

hyperparathyroidism

benign tumor causes; PTH excess leads to demineralization of bones (osteitis fibrosa cystica) making them porous

when disease is generalized and all bones are affected; this disorder is known as

von Recklinghausen disease

kidney stones

nephrolithiasis

addison's diease

chronic disorder caused by deficiency of cortical hormones; results when adrenal cortex is atrophied


autoimmune process in which circulating adrenal antibodies slowly destroy the gland; gland is destroyed 90% before symptoms appear; sodium and potassium metabolism may be lost through urination

cushing syndrome

cluster of symptoms produced by excessive amounts of cortisol, ACTH, or both in blood


slow healing wounds, thinning hair, moon face, buffalo hump, supracalvicular fat pad, increased facial hair, purple striae, easy bruising




alters carb and protein metabolism and electolyte balance- sodium retention

hair growth in unusual places

hirsutism

pheochromocytoma

produces excessive amounts of EPI and NE; most tumors are encapsulated and benign


produce high bp, rapid heart rate, palpitations, visual blurring etc

diabetes

most common pancreatic disorder; insufficient production of insulin or the bodys ability to use insulin



ketosis

diabetic condition when body cells are deprived of glucose; their principal nutrient

glucose in urine

glycosuria

abnormal thirst

polydispsia

abnormal hunger

polyphagia

type 1 diabetes

body does not produce sufficient insulin, patient needs glucometer; to determine amount of insulin they require; rotate injection sites to avoid injury

type 2 diabetes

most common form; onset later in life caused by the body's defciency in being able to utilize insulin, insulin resistant cells, etc


oral antidiabetics and weight loss may be prescribed

DKA diabetic ketoacidosis

diabetic coma; caused by too little insulin, failure to follow a prescribed diet, physical or emotional stress, or undiagnosed diabetes

chronic complications of diabetes

nephropathy, rentinopathy,

pancreatic cancer

tumors called adenocarcinomas; poor survival rate; exposure to chemicals, high fat diet and heavy coffee intake are associated with this

pituitary tumors

adenomas: benign tumors

thyroid carcinoma

hard nodule in lymph nodes; accompanied with an enlarged thyroid; sometimes causes hyperthyroidism

acromegaly

rare hormonal disorder in adulthood usually caused by a GH secreting pituitary tumor (adenoma) that promotes the soft tissue and bones of the face, hands, and feet to grow larger than normal

diuresis

increased formation and secretion of urine- DM and renal failure

glycosuria

abnormal amount of glucose in urine

graves disease

multisystem autoimmune disorder characterized by pronounced hyperthyroidism usually associated with enlarged thyroid gland (goiter) and exophtalmos

hirsutism

excessive distribution of body hair in women

hypercalcemia

calcium in blood is higher than normal; overactivity in parathyroid glands or cancer

hyperkalemia

potassium level in the blood is higher than normal; important for heart rhythm and muscle contraction- can be a serious problem that leads to cardiac arrest and death

hypervolemia

abnormal increase in volume of blood plasma; retention of large amounts of sodium and water

hyponatremia

lower than normal salt levels in blood; excessive amount of fluid in the body

insulinoma

tumor of the islet of langerhans of the pancreas

obesity

excessive accumulation of fat that excess the body's skeletal and physical standards; 20% or more above ideal body weight

morbid obesity

BMI of 40 or greater; 100 pounds over ideal body weight

panhypopituitarism

total pituitary impairment that brings about a progressive and general loss of hormone activity

pheochromocytoma

small chromaffin cell tumor usually located in the adrenal medulla, causing elevated heart rate and blood

thyroid storm

crisis of uncontrolled hyperthyroidism caused by the release into the bloodstream of an increased amount of thyroid hormone; also called thryotoxic crisis

virilism

masculinization or development of male secondary sex characteristics in a woman

expothalmometry

measures of the degree forward displacement of the eyeball in graves disease

parathyroidectomy

excision of one or more of the parathyroid glands, usually to control hyperparathyroidism

transsephenoidal hypophysectomy

endoscopic procedure to surgically remove a pituitary tumor through an incision in the sphenoid sinus without disturbing brain tissue; for cushing syndrome

thymectomy

excision of the thymus gland; remove tumors of thymus gland

thyroidectomy

excision of the entire thyroid gland (thyroidectomy), part of it (subtotal thyroidectomy) or a single lobe (thyroid lobectomy)

fasting blood sugar

test that measures glucose levels in a blood sample following a fast of at least 8 hrs

GTT glucose tolerance test

screening test in which a dose of glucose is administered and blood samples are taken afterward at regular intervals to determine how quickly glucose is cleared from the blood

insulin tolerance test ITT

diagnostic test in which insulin is injected into the vein to assess pituitary function, adrenal function, and to determine insulin sensitivity

thyroid function test

test that detects an increase or decrease in thyroid function

total calcium test

test that measures calcium to detect bone and parathyroid disorders

computed tomography

imaging technique that rotates an xray emitter around the area to be scanned and measures the intensity of transmitted rays from different angles (cross sectional image that appears as a slice)

magnetic resonance imaging (MRI)

noninvasive imaging technique that uses radio waves and a strong magnetic field rather than an xray beam to produce multiplanar cross sectional images; avoids hazards of ionizing radiation

radioactive iodine uptake

administration of radioactive iodine in pill or liquid form as a tracer to test how quickly the thyroid gland takes up iodine from the blood

thyroid scan

images of the thyroid gland are obtained after oral or intravenous administration of a small dose of radioactive iodine

afferent

going towards a central structure; to CNS

blood brain barrier

protective mechanism that blocks specific substances found in the bloodstream from entering delicate brain tissue

efferent

carry or move away from a central structure

limbic system

complex neural system located beneath the cerebrum that controls basic emotions and drives and plays an important role in memory (emotional)

neurilemma

additional external myelin sheath that is formed by schwann cells and found only on axons in the peripheral nervous system

ventricle

organ chamber or cavity that receives or hold fluid

neurons

transmit impulses

cell body

enlarged structure of the neuron that contains the nucleus of the cell and various organelles

dendrites

branching cytoplasmic projections carry impulses to the cell body

axons

carry impulses away from cell body; have myelin sheath, covering acts to accelerate impulse

PNS neural cells have

myelin sheath by schwanns cells; exterior surface forms nurilemma

CNS neural cells have

oligodendrocytes rather than schwann cells; short unmyelinated spaces between are nodes of ranvier

synapse

functional connection between two neurons or a neuron and effector organ

neurotransmitter

released at the end of its axon

neuroglia

cells that support neurons and bind them to other neurons or other tissues of the body; means nerve glue

astrocytes

star shaped neuroglia, 3D support for neurons and form tight sheaths around the capillaries of the brain; provide obstruction called the blood brain barrier to keep large molecules out

oligodendrocytes

responsible for developing myelin on axons and neurons in the CNS

microglia

smallest of neuroglia; possess phagocytic properties and become active in times of infection

ependyma

ciliated cells that line fluid filled cavities of the CNS; epescially ventricles of the brain

CNS

brain and spinal cord; white or gray matter

brain

has cerebrum, cerebellum, diencephalon, and brainstem

cerebrum

largest uppermost portion of the brain; 2 hemispheres divided by a longitudinal fissure

corpus callosum

joins the two hemispheres

insula

5th lobe of brain

cerebral surface is covered by folds called gyri

gyri are separated by furrows called sulci

thin layer called cerebral cortex covers the entire cerebrum and is composed of

gray matter (most information processing done here)

limbic system

emotional brain; controls behaviors like rage, fear, anger and emotional aspects

cerebellum

second largest structure of the brain; involves movement, posture, balance, coordination, refines muscular movement

diencephalon

interbrain; many smaller structures including the hypothalamus and thalamus

thalamus

sensory stimuli received and transmit them to appropriate centers in the cerebral cortex; can receive from cerebrum and relay them to efferent nerves

hypothalamus

regulates involuntary activities such as heart rate, body temperature, and fluid balance; controls many endocrine functions

brainstem

midbrain/ mesencephalon, medulla, pons


origin of the 10-12 pairs of cranial nerves and controls respiration, blood pressure and heart rate

spinal cord

transmits sensory impulses from the body to the brain and motor impulses from the brain to muscles and organs of the body

meninges

coverings are the dura mater, arachnoid mater, and pia mater

dura mater:

outermost covering of brain and spinal cord; tough and fibrous and composed of CT, also called pachymeninges

arachnoid

middle covering and has spiderweb appearance; subarachnoid space contains cerebrospinal fluid

collection of fluid in the brain

hydrocephalus

pia mater

innermost meninx, adheres directly to the brain and spinal cord, passes over the brain and follows contours of gyri and sulci; has BV and lymphatics


also called leptomeninges

PNS

all nervous tissue outside the spinal column and skull; cranial nerves and spinal nerves

cranial nerves

originate in base of brain and emerge; sensory motor, or mixture of both

sensory nerves

afferent, and receive impulses from the sense organs including the eyes, ears, nose tongue and skin

motor nerves

are efferent and conduct impulses to muscles and glands

mixed nerves

both sensory and motor fibers; can sense or produce impulses for actions

spinal nerves

31 spinal nerves, all are mixed nerves


each has dorsal point of attachment and ventral point of attachment


anterior root: motor fibers


posterior root: sensory fibers

somatic nervous system

motor impulses transmitted to muscles under conscious control

autonomic nervous system

motor impulses transmitted to glands and muscles not under conscious control

sympathetic division (ANS)

fight or flight

parasympathetic (ANS)

resting and digesting

cerebr/o

cerebrum

crani/o

cranium (skull)

encephal/o

brian

gangli/o

ganglion, knot or knot like mass

gli/o

glue, neuroglial tissue

kinesi/o

movement

lept/o

thin, slender

lex/o

word, phrase

mening/o


meningi/o

meninges, membranes covering the brain and spinal cord

myel/o

bone marrow; spinal cord

narc/o

stupor; numbness, sleep

neur/o

nerve

radicul/o

nerve root

sthen/o

strength

thalam/o

thalamus

thec/o

sheath (usually refers to meninges)

ton/o

tension

ventricul/o

ventricle of the heart or brain

-algesia


-algia

pain

-asthenia

weakness, debility

-esthesia

feeling

-kinesia

movement

-lepsy

seizure

-paresis

partial paralysis

-phasia

speech

-plegia

paralysis

-taxia

order, coordination

pachy-

thick

para-

near, beside, beyond

syn-

union; together, joined

uni-

one

involuntary movement

dyskinesia

neurology

branch of medicine

psychiatry

branch of medicine concerned with mental illness

radiculopathy or radiculitis

inflammation of the nerve root associated with the spinal column; pressure can cause pain and tingling; can be result of herniated disk, degenerative changes, etc

decompression surgery

to remove pressure in spinal column

cerebrovascular disease

abnormality of the cerebrum caused by disorders of BV of the rain;

stroke

cerebrovascular incident


3 (ischemic, intracerebral hemorrhage and subarachnoid hemorrhage)

80% of all strokes are

ischemic stroke

ischemic stoke

caused by narrowing of vessels in brain and neck due to atherosclerosis; narrowing hinders oxygen delivery; plaque can break lose and head downstream

intracerebral hemorrhage

caused by sudden rupture of artery in the brain; released blood compresses brain structures and destroys them

subarachnoid hemorrhage

blood is released into the space surrounding the brain; condition commonly caused by a ruptured aneurysm and is usually fatal

hemiparesis

weakness in one half of the body

hemiplegia

paralysis of half the body

inability to speak

aphasia

lack of muscle coordination

ataxia

TIA transient ischemic attack

1/3 of all strokes preceded by TIA

clot buster

thrombolytic medication

seizure disorders

characterized by sudden changes in behavior or consciousness

epilepsies

chronic seizure disorders

warning signal

aura

partial seizures

only portion of the brain is involved

generalized seizure

entire brain is involved

tonic clonic seizure/ grand mal

tonic (body becomes rigid)


clonic (uncontrolled jerking) recovery may take hours

status epilepticus

tonic clonic seizures follow after one another without an intervening period of recovery

parkinsons disease

shaking palsy; neurological disorder affecting the portion of the brain that is responsible for controlling movement


neurons degenerate; dopamine is lacking in the brain; must administer L dopa

MS multiple sclerosis

progressive degenerative disease of the CNS; inflammation, hardening and loss of myelin; conduction pathway short circuits; tremors and muscle weakness, patient is bedridden

alzheimer disease

causes memory loss and mental deterioration, small lesions called plaques develop in the cerebral cortex and disrupt the passage of electrochemical signals between cells

mental illness

array of psychological disorders and syndromes, behavioral paterns, etc



psychosis

mental disorder in which there is severe loss of contact with reality and sometimes delusions

neurosis

mental disorder caused by an emotion experienced in the past that overwhelmingly interferes or affects present emotion (phobias, hysterias, OCS)

affective disorder

psychological disorder in which the major characteristic is an abnormal mood; usually mania or depression

anorexia nervosa

eating disorder characterized by a refusal to maintain adequate weight for age and height and a desire to stay thin

anxiety

psychological worry disorder characterized by excessive pondering, lack of interest, worry, and dreadful feelings

attention deficit hyperactivity disorder

disorder affecting children and adults characterized by impulsiveness, overactivity,, and the inability to remain focused on a task

autism

developmental disorder characterized by extreme withdrawal and an abnormal absorption in fantasy usually accompanied by inability to communicate

bipolar disorder

mental disorder that causes unusual shifts in mood, emotion, energy and the ability to function; also called manic depressive illness

bulimia nervosa

eating disorder characterized by binging and purging

depression

mood disorder associated with sadness, despair, discouragement and commonly feelings of low self esteem, guilt and withdrawal

mania

mood disorder characterized by mental and physical hyperactivity; disorganized behavior and excessively elevated mood

neurosis

nonpsychotic mental illness that triggers feelings of distress and anxiety and impairs normal behaviors

panic attack

sudden intense feeling of feat that comes without warning and is not attributable to any immediate danger

psychosis

major emotional disorder in which contact with reality is lost to the point that the individual is incapable of meeting the challenges of daily lifei

intracranial tumors

that originate in the brain tissue are called primary intracranial tumors ; headache

papilledema

optic disk in back of eyeball swells

agnosia

inability to comprehend auditory, visual, spatial, olfactory, or other sensations even though the sensory sphere is intact

asthenia

weakness, debility, loss of strength

ataxia

lack of muscle coordination in the execution of voluntary movement

closed head trauma

injury to head in which the dura mater remains in tact and brain tissue is not exposed

brain hits inside of the skull

coup

opposite side of brain hits the skull

contrecoup

coma

abnormally deep unconsciousness with an absence of voluntary response to stimuli

concussion

injury to the brain, occasionally with transient loss of consciousness as a result of trauma to the head

convulsion

any sudden and violent contraction of one or more voluntary muscles

dementia

broad term that refers to cognitive deficit, including memory impairment

dyslexia

inability to learn and process written language, despite adequate intelligence, sensory ability, and exposure

guillian barre syndrome

autoimmune condition that causes acute inflammation of the peripheral nerves in which myelin sheaths on the axons are destroyed, resulting in decreased nerve impulses, loss of reflex response and sudden muscle weakness


viral GI infection

herpes zoster

acute inflammatory eruption of highly painful vesicles on the trunk of the body or occasionally the face; also called shingles

huntington chorea

inherited disease of the CNS characterized by quick involuntary movements, speech disturbances, and mental deterioration

hydrocephalus

accumulation of fluid in the ventricles of the brain, causing increased intracranial pressure, thinning of brain tissue, and separation of cranial bones

acquired hydrocephalus

develops at birth; or any time afterward as a result of injury or disease

congenital hydrocephalus

during fetal development/genetic abnormalities

lethary

abnormal inactivity or lack of response to normal stimuli

anencephaly

congenital deformity in which some or all of fetal brain is missing; stillborn dies

spina bifida

congenital deformity of the neural tube which fails to close during fetal development; also called neural tube defect

meningocele spina bifida

spinal cord develops properly but meninges protrude through spine

myelomeningocele spina bifida

most severe form of spina bifida, spinal cord and meniges protrude through spine

occulta spina bifida

one or more vertebrae are malformed and spinal cord is covered with a layer of skin

palsy

paralysis usually partial and commonly characterized by weakness and shaking or uncontrolled tremor

bell palsy

facial paralysis caused by a functional disorder of the 7th cranial nerve

cerebral palsy

type of paralysis that affects movement and body position and sometimes speech and learning ability

paralysis

loss of voluntary motion in one or more muscle groups with or without loss of sensation

hemiplegia

loss on one side of the body; unilateral

paraplegia

loss of both lower limbs

quadriplegia

paralysis of arms and legs commonly resulting in bowel, bladder and sexual dysfunction

paresthesia

sensation of numbness, prickling, tingling, or heightened sensitivity

poliomyelitis

inflammation of the gray matter of the spinal cord caused by a virus; commonly resulting in muscle deformity and paralysis

reye syndrome

acute encephalopathy and fatty infiltration of the brain, liver and possibly the pancreas and heart, kidney, spleen, and lymph nodes

syncope

brief loss of conciousness and posture caused by a temporary decrease of blood flow to the brain; FAINTING

elecroencephalography

recording of electrical activity in the brain, whose cells emit distinct patterns of rhythmic electrical impulses

electromyography

recording of electrical signals, action potentials, that occur in muscle when it is at rest and during contraction to assess muscular disease or nerve damage

lumbar puncture

needle puncture of the spinal cavity to extract spinal fluid for diagnostic purposes; introduce anesthetic agents or remove fluid to allow for other fluids; also called spinal tap

nerve conduction velocity

test that measures the speed at which impulses travel through a nerve

cryosurgery

exposes abnormal tissue to extreme cold to destroy it

stereotactic radiosurgery

precisely focused stereostatic radiation beams are used to treat tumors and other abnormal growths in the brain, spinal column, and other body sites and delivers high doses of radiation to the tumor with minimal exposure to surrounding healthy tissue

thalamotomy

partial destruction of the thalamus, to treat intractable pain; involuntary movements including tremors in parkinsons disease; or emotional disturbances

trephination

technique that cuts a circular opening into the skull to reveal brain tissue and decrease intracranial pressure

ventriculoperitoneal shunting

relieves intracranial pressure due to hydrocephalus by diverting excess cerebrospinal fluid from the ventricles to the peritoneal or thoracic cavity

cerebrospinal fluid analysis

lab test to examine a sample of the fluid surrounding the brain and spinal cord; used to diagnose disorders of the central nervous system; including viral and bacterial infections

angiography

radiographic image of the inside of a blood vessel after injection of a contrast medium

computed tomography angiography

angiography in combination with a CT scan to produce high resolution 3D vascular images of the blood vessels

discography

CT scan of the lumbar region after injection of a contrast medium to detect problems with the spine and spinal nerve roots

echoencephalography

ultrasound technique used to study intracranial structures of the brain and diagnose conditions that cause a shift in the midline structures of the brain

magnetic source imaging

noninvasive neuroimaging technique to pinpoint the specific location where seizure activity originates and enable custom surgical treatment for tumor and epileptic tissue resection; MEG

myelography

radiographic examination to detect pathology of the spinal cord; including the location of a spinal cord injury, cysts and tumors following contrast medium injection

positron emission tomography

computed tomography that records the positrons emitted from a radiopharmaceutical and produces a cross section image of metabolic activity in body tissues to determine presence of disease

psychostimulants

reduce impulsive behavior by increasing the level of NTs