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28 Cards in this Set

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How do light microscopes work?
They use glass lenses to refract light and produce a magnified image
🔬
How do you calculate the magnification of a light microscope?
Multiply the magnification of the eye piece lens by the objective lens
🔬x🔭
When were light microscopes and electron microscopes invented?
Light microscopes; early 17th century
Electron microscopes; 1930s
How do electron microscopes work?
They shine a beam of electrons through a sample. The wavelength of electrons is much smaller than the wavelength of light, so it is magnified more and reveals more detail.
What features are found in bacterial cells?
Cytoplasm
Cell wall
Plasmid DNA
Chromosomal DNA
Flagella
What are chromosomes, and how many pairs do human cells have?
Long coiled molecules of DNA, 23
What is a gene?
A section of DNA, which codes for a particular protein
What does a DNA molecule consist of?
2 strands, which are coiled to form a double helix. The strands are linked by a series of paired complementary bases;
Adenine - Thymine
Cytosine - Guanine
What holds the bases of DNA together?
Weak hydrogen bonds
Who discovered the double helix model of DNA? When and where?
James Watson and Francis Crick at Cambridge University in 1953
What is genetic engineering?
Removing a gene from one organism and inserting it into another. This can include animals, plants and microorganisms
What are transgenic animals?
Animals that have been genetically modified by having genes from another species inserted into their species
How has rice been genetically modified? 🍚
To contain a beta-carotene gene to reduce Vitamin A deficiency in humans. In the countries where vitamin A deficiency occurs the most (Africa and South East Asia) rice is a staple food.
How is insulin produced on a large scale?
The human gene for insulin has been inserted into bacteria, which are then used to produce the hormone on a large scale to treat diabetics.
How do scientists produce herbicide-resistant crops?
1◽ Find a wild plant that is resistant to the herbicide
2◽Transfer the resistant gene to crop plant's DNA by a vector
3◽Allow crops to grow, treat with herbicide to kill weeds
3◽New plants are resistant to herbicide and are not killed
Why do the offspring produced by asexual reproduction have the same genes as the parent?
They get their genes from one parent only, so they are clones of their parent
What is mitosis?
The division of a cell nucleus to produce two cell nuclei with genetically identical sets of chromosomes
Why does mitosis happen?
to produce new cells for growth, to repair damaged tissues and in asexual reproduction
What are clones? 🐏🐏🐏🐏🐏
Individuals that are genetically identical
What is differentiation?
The process by which cells become specialised to allow them to perform a particular job efficiently
What's special about stem cells?
They are undifferentiated (unspecialised), which means they could, theoretically, differentiate into any type of cell
What is a potential use of stem cells?
They could be used to replace damaged cells as tissues to help in the treatment of diseases or injuries
How are stem cells made to develop into other cells?
By adding different chemicals, called growth factors, they are made to develop into:
▫insulin-producing cells in the pancreas
▫heart muscle cells
▫blood cells
▫neurones (nerve cells)
▫bone marrow cells
When does a person develop Parkinson's disease?
When the neurones in the brain stop producing dopamine, a chemical that the neurones use to communicate with each other. When dopamine is not produced, the brain is unable to coordinate the movements of the body (amongst other things)
How could stem cells be used as a potential cure for Parkinson's disease?
If stem cells could be made into brain neurones and made to produce dopamine, this could provide a cure for the disease.
Where can stem cells come from?
▫Bone marrow
▫Embryos (embryonic stem cells)
What factors can make DNA mutations?
▫UV radiation
▫viruses
▫some chemicals
▫errors during DNA replication
What are enzymes?
▫Biological catalysts
▫They are protein molecules, which control the rate of chemical reactions that occur in living organisms