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163 Cards in this Set

  • Front
  • Back
epithelial tissue
covers surfaces, lines inside of organs and body cavities and forms glands
connective tissue
protects and supports body, binds organs together, provides immunity
muscle tissue
movement and generation of heat
nervous tissue
initiate and transmits impulses (action potentials ) that control and coordinate the functioning of the body
simple epithelium
single layer of cells. functions: covers surfaces, allows diffusion of gases, filters blood, secretes cellular products and absorbs nutrients
stratified epithelium
2 or more layers of cells. mostly found in areas of high wear and tear. function: selective movement of materials, protection
squamous epithelial cells
flat cells (skin). allows substances to diffuse through and filter.
cuboidal epithelial cells
cube shaped cells (kidney tubules) involved in secretion and absorbing
columnar epithelial cells
shaped like columns. some have cilia on them (trachea). Involved in secretion and absorbing
pseudostratified epithelial cells
appear stratified but arent
transitional epithelial cells
cell shape and number of layers changes
skeletal muscle
what is normally thought as "muscle". attaches to bones, has striations, voluntary, function is body movement.
cardiac muscle
muscle of the heart. has striations, involuntary, function: contraction provides the major force for moving blood through the blood vessels. Has branching fibers, intercalated disks containing gap junctions joining the cells to each other
smooth muscle
located in walls of hollow organs, blood vessels, eyes, glands, skin. involuntary. Function: movement of food through the digestive tract, emptying of the urinary bladder, regulation of blood vessel diameter, change in pupil size, contraction of many gland ducts, movement of hair, and many more. has gap junctions, and no striations.
nervous tissue
found in the brain, spinal cord, and nerves. characterized by the ability to conduct electric signals called action potentials. Consists of neurons and neuroglia
neurons
carry the impulses that control and coordinate the body. cell body with nucleus, has dendrites (input) and an axon (output)
neuroglial cells
do not carry impulses but support neurons in different ways. supports cells of brain, spinal cord, and peripheral nerves. functions: nourish, protect, and insulate neurons.
hyaline cartilage
connective tissue. most abundant; very strong but not very flexible (collagen). Found at end of long bones, rib area, respiratory system, embryonic skeleton
fibrocartilage
connective tissue. tough but flexible (lots of collagen). found in the intervertebral disks, the pubic symphysis, the tempomandibular joints and the knee.
elastic cartilage
very flexible (collagen and elastin fibers) found in pinna (external ears).
articular cartilage
a specialized form of hyaline cartilage that covers the ends of bones at joints. connective tissue. no perichondrium, avascular, aneural (no nerves). reduces friction, synovial fluid provides nourishment.
adipose tissue
connective tissue. little extracellular matrix surrounding cells. function: packing material, thermal insulator, energy storage, and protection of organs against injury from being bumped or jarred.
cancellous and compact bone
bones that are made of connective tissue.
blood
connective tissue. cells and a fluid matrix. transports oxygen, carbon dioxide, hormones, nutrients, waste products, and other substances; protects the body from infections and is involved in temperature regulation.
melanin
molecules colors ranging from brown to black. present in skin. exposure to UV light stimulates the production.
endocrine glands
gland becomes separated from the epithelium from which it developed. Secretions do not go through a duct. Secretions are called hormones. Ex. pituitary gland, adrenal gland
exocrine glands
gland maintains an open contact with the epithelium from which it developed. Secretions that are produced flow through a duct to get to the surface or the lumen surface of the organ. Ex. mucus, digestive glands
merocrine
cells of the gland produce secretions by active transport or produce vesicle that contain secretory products, and the vesicles empty their contents into the duct through exocytosis. secrete products with no loss of actual cellular material. cools body, most common type, opens directly to skin through sweat pores. Ex. sweat glands (sudoriferous).
apocrine
secretory products are stored in the cell near the lumen of the duct. a portion of the cell near the lumen containing secretory products is pinched off the cell and joins secretions produced by a merocrine process. discharge fragments of the gland cells in the secretion. contributes to cytoplasm. opens into hair follicles superficial to sebaceous glands. present in axillae, genitalia, and around anus. active at puberty
holocrine
secretory products are stored in the cells of the gland. entire cells are shed by the gland and become part of the secretion. the lost cells are replaced by other cells deeper in the gland. ex. Sebaceous glands of the skin
sebaceous glands
structurally simple or compound. in dermis; usually associated with hair follicles. produce sebum (oily white substance, rich in lipids) to prevent drying, protects against some bacteria. Holocrine gland. Found in lips, eyelids, genitalia
ceruminous glands
modified merocrine sweat glands. found in external auditory meatus. produces cerumen (earwax). protects from dirt and insects, and protects eardrum.
mammary glands
modified apocrine sweat glands. found in breasts, produces milk, controlled by hormones.
embryonic tissue
endoderm, mesoderm, ectoderm forms...
endoderm
inner layer of embryonic tissue. forms lining of digestive tract and deriatives
mesoderm
middle layer of embryonic tissue. forms tissues such as muscle, bone, blood vessels
ectoderm
outer layer of embryonic tissue. forms skin and neuroectoderm
5 manifestations of inflammation
redness, heat, swelling, pain, function disturbance
fibrous joints
consist of 2 bones that are united by fibrous connective tissue; has little or no movement and does not have a joint cavity. EX. sutures and gomphoses
sutures
immovable fibrous joint found in skull; resembles seams
gomphoses
fibrous joint. peg shaped structures that fit into sockets and held in place by connective tissue (ex. the joints between the teeth and their sockets)
cartilaginous joints
hyaline or fibrous cartilage ex. symphysis, synchondrosis
symphysis
a slightly movable joint where fibrocartilage unites the 2 bones. ex. the symphysis pubis
synchondrosis
connecting material is hyaline cartilage; little or no movement. most are temporary, with bone eventually replacing them to form synostoses (when 2 bones join together across a joint to form a single bone); others persist throughout life. temporary - ephiphyseal plates of long bones. permanent- between ribs and sternum.
synovial joints
joints that contain synovial fluid and are freely movable. many of the joints in the appendicular skeleton: elbow, hip, knee. the ends of the bones (articular surfaces) are covered by articular cartilage (thin layer of hyaline cartilage that provides a smooth surface)
plane (gliding) joints
2 opposed flat surfaces of about equal size in which a slight amount of gliding motion can occur between the bones. Ex. articular processes between vertebrae. Ex, acromioclavicular, carpometacarpal, costovertebral, intercarpal, intertarsal, intervertebral, sacroiliac, tarsometatarsal
saddle joints
2 saddle shaped articulating surfaces oriented at right angles to each other so that complementary surfaces articulate with each other. carpometacarpal pollicis, intercarpal, sternoclavicular
hinge joints
uniaxial joints consisting of a convex cylinder in one bond applied to a correspoonding concavity in the other bone. ex. elbow and knee joints. cubital, genu, interphalangeal, talocrual
pivot joints
uniaxial joints that restrict movement to rotation around a single axis, Ex: articulation between the head of the radius and the proximal end of the ulna; articulation between the head of the radius and proximal end of the ulna; articulation between the dens of the axis and the atlas. atlantoaxial, proximal radioulnar, distal radioulnar
ball and socket joints
consist of a ball at the end of one bone and a socket in an adjacent bone into which a portion of the ball fits. Ex. shoulder and hip joints. coxal, glenohumeral
ellipsoid joints (condyloid)
biaxial modified ball and socket joints where articular surfaces are ellipsoid in shape rather than spherical. ex. alantoocipital joint. metacarpophalangeal, metatarsophalangeal, radiocarpal, temporomandibular
acromioclavicular
plane joint. acromion process of scapula and clavicle. slight movement
carpometacarpal
carpals and metacarpals 2-5. slight movement. plane joint.
costovertebral
plane joint. ribs and vertebrae. slight movement.
intercarpal
plane joint. between carpals. slight movement.
intertarsal
between tarsals. plane joint. slight movement
intevertebral
between articular processes of adjacent vertebrae. plane joint slight movement
sacroiliac
plane joint, between sacrum and coxal bone (complex joint with several planes and synchondroses) slight movement
tarsometatarsal
tarsals and metatarsals. slight movement. plane joint.
carpometacarpal pollicis
carpal and metacarpal of thumb. 2 axes. saddle joint.
intercarpal
saddle joint, between carpals slight movement
sternoclavicular
saddle joint. manubrium of sternum and clavicle. slight movement.
cubital
elbow. joins humerus, ulna, and radius. hinge joint. one axis.
genu
hinge joint. knee. joins femur and tibia. one axis
interphalangeal
hinge joint. between phalanges. one axis
talocrural
ankle. hinge joint. joins talus, tibia , and fibula. multiple axis, one predominates.
atlantoaxial
pivot joint. joins atlas and axis. rotation.
proximal radioulnar and distal radioulnar
pivot joint. joins radius and ulna. rotation
coxal
hip. ball and socket joint. joins coxal bone and femur. multiple axes
glenohumeral
shoulder. ball and socket joint. joins scapula and humerus. multiple axes
atlantooccipital
ellipsoid joint. joins atlas and occipital bone. 2 axes
metacarpophalangeal
knuckles. ellipsoid joint. joins metacarpals and phalanges. 2 axes.
metatarsophalangeal
ellipsoid joint. joins metatarsals and phalanges. 2 axes
radiocarpal
wrist. ellipsoid joint. joins radius and carpals. multiple axes
temporomandibular
ellipsoid joint. joins mandible and temporal bone. multiple axes, one predominates.
mucous membranes
consist of epithelial cells, their basement membrane and the lamina propria. lines cavities and canals that open to the outside (ex. digestive system, reproductive system, excretory system, and respiratory system.). many contain goblet cells or mucous glands that produce mucus. function: protection, absorbtion, and secretion.
primary union. aka first intention
heals wounds when edges are close together. wound fills with blood; clot forms, fibrin binds edges of wound together. scab forms. inflammatory response. fibroblasts from surrounding connective tissue migrate into clot and produce collagen and other components. revascularization. fibrin is broken down and removed. granulation tissue replaces tissue.
secondary union aka second intention
heals wounds when the edges are far apart. since edges are further apart, the clot may not close the gap completely. takes much longer for epithelial cells to regenerate and cover the wound. inflammatory response is greater. more granulation tissue forms. wound contraction occurs. (disfiguring scars)
first degree burn
involves only the surface epidermis; mild pain and redness. no blisters. typical sunburn
second degree burn
destroys all of the epidermis and may destroy some of the papillary region of the dermis; redness, blisters, edema, and pain. no injury to accessory skin structures. partial thickness burns
third degree burn
destroys epidermis, dermis, and epidermal derivatives. skin functions are lost. if burn exceeds of 70% of body, person usually dies.
osteoporosis
disease which bones become porous and fragile and more likely to break or fracture (esp. in hip, wrist, spine). loss in bone mass (more resorption, less formation). primarily affects women (esp. small framed, caucasian and asian) but both sexes suffer from disease. occurence increases with age. seen in young people whose caloric intake is inadequate or who suffer from eating disorders. also common in inactive people, more prevalent in smokers and alcoholics. "silent" disease, without symptoms, bones become weak and break in situations where healthy bones would not.
scoliosis
lateral bend of the vertebral column, usually in the thoracic region
kyphosis
hump back. exaggeration of the thoracic curvature.
lordosis
hollow back. exaggeration of lumbar curvature; seen in pregnancy and also known as sway back.
rheumatoid arthritis
caused by transient infection or autoimmune disease (not curable). 2nd most common type of arthritis; genetic predisposition may exist. body attacks cartilage and synovial membranes of joints, leading to inflammation of the joint, swelling, pain. if not treated, the synovial membranes become thicker and produce more fluid (water on the knee). also may be abnormal growth of tissue formed by the inflamed synovial membrane - pannus (clothlike layer). in advanced stages, destruction of the aricular cartilage of the bones with in the joint results in those bones ossifiying together
osteoarthritis
wear and tear. the most common type of degenerative joint disease arthritis. usually associated with aging and slowed metabolic rates. there is deterioration of the articular cartilage but no synovial membrane involvement. tends to occur in weight bearing joints (knees) and in overweight individuals. there is inflammation, pain, and decrease in the use of the joint
gout
arthritis cases (5%). painful metabolic disease involving the joins. it results from deposits of needle like crystals of uric acid in the joint space between 2 bones. produces too much uric acid, than can be excreted. uric acid builds up in the blood and some will form salt crystals that deposit in the joints, causing pain and decrease in motion. bones can also fuse because the crystals will wear away at the cartilage. usually seen in men with a family history and usually in the joints of the big toe.
lyme disease
ticks carry as vector. shows bullseye target. inflammes joints. symptoms: joint pain, flu like symptoms
decubitus ulcer
bedsore or pressure sore in immobile patients. caused by prolonged deficiency of blood to tissues. (esp. overlying a bony projection) due to body weight. the deficiency results in necrosis of the skin and microbe entry-- ulcers. seen on buttocks, sacrum, and heels. turning is necessary
psoriasis
chronic skin condition in which the stratum basale cells divide 7 times more frequently than normal, keratin production is abnormal, and the unusually thick stratum corneum desquamates to produce large, silvery scales. if these are scraped away, bleeding occurs. may be a genetic disease in which the immune system stimulated hyperplasia. anti cancer drugs sometimes helpful, as is UV light therapy.
vitiligo
the development of patches of white skin due to abnormal or lack of melanocytes in that area. may be an autoimmune response.
cyanosis
a bluish or purplish discoloration of skin due to defiecient oxygentation of blood.
jaundice
yellowish pigmentation of skin, tissues, and certain body fluids caused by deposition of bile pigments that follows interference with normal production and discharge of bile or excessive breakdown of red blood cells.
basal cell carcinoma
accounts for 75% of all skin cancer. tumors arise from the stratum basale of the epidermis and extend into dermis (open ulcer. usually slows metastasis. typically cured by surgical removal or radiation therapy
squamous cell carcinoma
skin cancer that arise from stratum spinosum keratinocytes. usually slow metastasis, but can cause death
malignant melanoma
less common, life threatening cancer arising from melanocytes, many times found with in a pre existing mole. metastasize rapidly, so early treatment is crucial. watch areas that change in pigment, size and irregular borders. often fatal.
thoracic and sacral
infant is born with these 2 curvatures..
cervical
as the child lifts his head this curvature develops
lumbar
as the chid becomes bipedal this curvature develops.
vitamin d
important for absorption of calcium from the intestines (needed for mineralization) and for regulation of calcium and phosphorus in bone mineralization. ex. rickets may occur if there is a lack of this vitamin during childhood.
vitamin c
ascorbic acid. necessary for collagen synthesis. ex. if there is a deficiency of this vitamin scurvy may occur. lack causes wounds not to heal, teeth to fall out.
determines skin color
skin pigments (melanin, carotene), blood circulation (hemoglobin), thickness of stratum corneum all....
causes skin to age
slower skin repair, skin sags and wrinkles, becomes drier, number of functioning melanocytes decrease in most areas, but increase in others. lack or decrease in melanin production... all cause...
keratin
protein mixture produced by most cells of the epidermis
soft keratin
found in skin
hard keratin
found in nails and external parts of hair. more durable cells, cells dont desquamate, more sulfur.
osteoblasts
build bone, cells produce collagen and proteoglycans. secrete osseous matrix on surface of existing bone (appositional growth) all vesicles are released by exocytosis. no mitosis, cell contact via gap junctions.
osteoclasts
carve bone. large, multinucleated cells. thought to derive from a type of phagocytic white blodd cell. found in contact with calcified bone surface. responsible for resorption (breakdown) of bone matrix.
desquamation
mitosis in deepest layers produces new cells, older cells get pushed to the surgace, and get sloughed off. cells get dried out. seen in epidermis.
woven bone
collagen fibers randomly oriented. fetal development and during fracture repair. remodeled to form lamellar bone.
lamellar bone
mature bone. thin sheets of layer. collagen fibers parallel, and at an angle to adjacent. osteocytes within lacuna.
bone remodeling
converts woven bone to lamellar bone, involved with bone growth, changes bone shape, adjustment of bone to stress. The ongoing replacement of old bone tissue by new bone tissue -- osteoclasts remove old bone (resorb it on the inside) and osteoblasts deposit new bone (to the outside). Formation of new osteons in compact bone. Bone tissue is never at rest and changes are constantly taking place. Takes place at different rates (depending on the bone and the persons age); EX. the distal portion of the femur will be replaced every 4 months, whereas the shaft is not replaced completely one the person reaches adulthood. Causes diameter of medullary cavity to increase as the bone increases in length and width.
bone repair steps
hematoma formation, callus formation, callus ossification
hematoma formation
first step of bone repair.-- when a fracture occurs, the blood vessels in the area are broken --- the blood rushes into the injured area and a clot forms 6-8 hours after the injury. Osteocytes around the site die due to a disruption of blood (and O2). Inflammation occurs, bringing phagocytic cells and osteoclasts into the area to clean up the dead and dying bone cells (area typically swells).
hematoma
a localized mass of blood confined within an organ or space
callus formation
Second step of bone repair..The connective tissue will be invaded by chondroblasts from the periosteum and endosteum of the broken bone. Cartilage is formed and chondroblasts become chondrocytes.
Callus ossification
Third step of bone repair...similar to fetal development, the chondrocytes will eventually be replaced by osteoblasts and new bone will be formed.
remodeling of bone
the final phase of fracture repair is remodeling of the bony callus (from woven to compact bone) by osteoblasts and osteoclasts. Repair may take a long time (sometimes over a year), but may be so complete that no evidence of a break remains. However, the repaired area may remain slightly thicker.
parts of a long bone
diaphysis, epiphysis, articular cartilage, epiphyseal plate, medullary cavity
callus
mass of tissue that forms at the fracture site and attempts to connect the broken ends of the bone
diaphysis
shaft
epiphysis
extremity or end
epiphyseal plate
area where bone grows longer; originally hyaline cartilage, but becomes ossified as person ages and then is known as.. line. Seperates epiphysis from diaphysis.
medullary cavity
space within diaphysis; filled with marrow
nail
made of plates of tightly packed, hard, kerantinized cells. lies over the epidermis of the dorsal, distal portion of the digits. protects the ends of the digits. Composed of stratum corneum.
lunula
lacks melanocytes. the edge of the germinal matrix looks white and is crescent shaped.
tendons
connects muscle to bone
ligaments
connects bone to bone, cartilage to bone
intervertebral disks
found between the bodies of adjacent vertebrae. composed of fibrocartilage. shock absorbers. provide additional support. prevents the vertebral bodies from rubbing against each other. allow the vertebral column to be somewhat flexible
desmosomes
disk shaped structures with especially adhesive glycoprotein that bind cells to one another and intermediate filaments extends into cytoplasm.
hemidesmosomes
attach epithelial cells to basement membrane.
gap junctions
specialized contact regions; communication, coordination. aids intercellular communication. Important in coordination function of cardiac and smooth muscle tissue
tight junctions
protective seal. holds cells together and form a permeability barrier.
functions of the skeletal system
support, protection, movement, storage, hematopoiesis
support
bones provide a hard framework that anchors soft tissue of the body. ex. cartilage & ligaments, bones
protection
to internal organs by this hard tissue that overlies and/or surrounds them. ex. cranium and brain, spinal cord and vertebral column.
movement
bones provide leverage for muscle contraction. ex. joints, ligaments, smooth cartilage.
storage
minerals (Ca2+) and fat in yellow bone marrow. Ex. minerals in blood stored in bone. EX. adipose stored with in bone cavities.
hematopoiesis
the production of blood cells occurs in red bone marrow of certain bones (cranium, sternum, ribs, vertebrae, sacral, and hip bones (Os coxae), head of femur and humerus)
long bones
shape is longer than they are wide. (upper and lower limbs) ex. femur
short bones
as broad as they are wide (carpals and tarsals) ex. carpal
flat bones
thin, flattened, curves (some skull bones, ribs, sternum, scapulae) ex. paretial
irregular bones
dont fit in other bone shape categories. (vertebrae, facial bones) ex. Sphenoid
layers of skin in the epidermis
(deepest layer) stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, stratum corneum (most superficial layer)
stratum basale
simple cuboidal or simple columnar epithelium (keratinocytes), hemidesmosomes, desmosomes, keratonicytes undergo mitosis every 19 days.
stratum spinosum
8-10 layers, formation of additional keratin fibers; transfer of melanin to keratinocytes, lamellar bodies form, some mitosis occuts (most superficial layer in which it does)
stratum granulosum
2-5 layers, accumulation of keratohyalin protein granules in cytoplasm, lamellar bodies release lipid contents into intercellular space, protein envelope formation, nuclei degeneration, cell death.
stratum lucidum
several layers of dead cells, thin clear zone, keratohyalin dispersed around keratin fibers, cells appear transparent, this layer is generally absent from thin skin.
stratum corneum
most superficial stratum, 25 or more layers of dead squamous cells that are cornifed- contain a hard protein envelope filled with keratin (responsible for structural strength), cells are surrounded by the lipids released from the lamellar bodies
autopsy
examination of organs of a dead body to determine the cause of death or to study the changes caused by a disease.
biopsy
process of removing tissue from living patients for diagnostic examination
carcinoma
malignant neoplasm derived from epithelial tissue
sarcoma
malignant neoplasm derived from connective tissue
cyanosis
a bluish or purplish discoloration of skin due to deficient oxygenation of blood.
jaundice
yellowish pigmentation of skin, tissues and certain body fluids caused by the deposition of bile pigments that follows interference with normal production and discharge of bile or excessive breakdown of red blood cells
frost bite
most common type of freezing injury. when skin temperature drops below freezing, the skin freezes and ice crystal formation damages tissues.
vitamin D
fat soluble vitamin produced from precursor molecules in skin exposed to UV light; increases calcium and phosphate uptake from the intestines
spina bifida
when vertebral laminae partly or completely fail to fuse (or even form) during fetal development. most common in lumbar region if the defect is severe and involves the spinal cord, it may interfere with normal nerve function below the point of the defect.
foramen
hole on bone that allows soft tissue (vessels, nerves) to pass through
suture
Immovable joint in skull – appears as a line in between flat bones of the skull.
fossa
indentation
condyle
a large, rounded articular process; rounded protrusion