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103 Cards in this Set
- Front
- Back
Upon leaving the bronchial walls of the capillary bed, O2 poor blood can go 2 ways(1) 25-33% drains thru true bronchial veins & into the right atrium and (2) the remaining 64-75% drains directly into the pulmonary veins. (2) does what to the pulmonary venous blood?
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mixes poor O2 blood with well oxygenated blood
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Normal anatomic shunting makes it so that systemic arterial blood can never have the same partial pressure of O2 as _____.
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alveolar gas
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Define anatomical shunting
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The mixing of unoxygenated blood with oxygenated blood.
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The ___ connections between bronchial & pulmonary circulation causes anatomical shunting( also called bronchopulmonary-arterial anastomoses).
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vascular
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Pulmonary venous blood is normally identical to ____ blood.
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arterial
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The _____ is the source of innervation for the lung airways.
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autonomic nervous system(autonomic sensory & motor nerves)
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Skeletal muscles of chest wall & diaphragm are innervated by the ___.
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somatic nervous system
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The ____ &___ are divisions of the autonomic system that control most of the body's visceral functions(soft organs of the thoracic & abdominal cavities).
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sympathetic & parasympathetic
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The paired ___ nerves supply motor inervation to the diaphragm. they originate from right and left cervical nervous plexus as branches of c3-c5.
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phrenic
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The ___ nerves are spinal nerves that innervate muscles between ribs & intercostal muscles.
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intercostal
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____ is the transmitter used in sympathetic innervation of the lungs.
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norepinephrine
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___ is the transmitter used in the parasympathetic innervation of the lungs.
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acetylcholine
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The external landmark for tracheal division into mainstem bronchi is the ___.
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sternal angle(aka angle of louis)
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This external angle marks where you must NOT go down to when doing compressions.
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xiphoid process
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The primary muscles for respiration are the ___ &___.
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diaphragm & intercostals
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The primary muscles for inspiration are the _____.
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accessory muscles
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The accessory muscles are ___ & ___.
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Scalene & sternocleidomastoid
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Movement of the ____ & _____ are responsible for pleural pressure changes.
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lungs& chest
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What is the (normal) pleural pressure value ?
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755 mm Hg(negative under normal quiet breathing)
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What is the (normal)pleural pressure value for inspiration & expiration?
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-8 & -6
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___(or distensibility) is the measure of the lung's opposition to inflation.
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Compliance
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What is the normal value for compliance?
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.2L/cm H2O
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____/_____ is the change in pressure required to produce a unit of volume change cm H2O/L. It is the mathematical reciprocal of compliance.
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Resistance/elastance
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Another term for airway resistance is RAW. ____ is the normal RAW in adults.
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05-1.5 cm H2O/L/second
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Surfactant forms a mono molecular layer over pulmonary alveolar surfaces, preventing alveolar collapse at lower lung volumes by ______.
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reducing alveolar surface tension
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Where is surfactant formed/produced by _____ and stored in lamellated bodies to be secreted onto the alveolar surface.
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type II pneumocytes
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Exchange of O2 with CO2 across capillary membranes by simple diffusion is called ___.
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internal respiration
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Exchange of gases from outside with the lungs(into the body) is called ___.
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external respiration
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How does a normal diaphragm move during inspiration (directional)?
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down
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How does a normal diaphragm move during expiration(directional)?
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up
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How much does a normal diapram move (distance)?
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1-2cm(10 with max)
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How does a floppy diaphragm move during inspiration & expiration?
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the diaphragm decreases the AP diameter of the thoracic cavity on inspiration & moves very little on expiration( check expiration part again)
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What diseases would cause problems with innervation of the diaphragm?
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neuromuscular diseases and trauma
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A huge part of clearance is the _______. The ciliated epithelial cells move in a forward motion, causing the trapping of foreign matter. The forward motion also moves the mucus upward & hopefully outward(this is mucokinesis)!
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mucociliary escalator
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The top layer of the airway tissue mucus is a ____ blanket, the next layer is the ___(water)layer where the tips of the ciliated epithelial cells "do the wave".
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gel, sol
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What does the upper airway consist of?
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nose, oral cavity, pharynx and larynx
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What are the functions of the nose ?
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Air conditioning, filtering, warming and humidifying
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What is another name for conchae?
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turbinates
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The function of the conchae or turbinates is to ______.
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increase surface area
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What types of cells are in the mucous of the lung?
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immungolobiulins and inflammatory cells
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The larynx marks the transition between what to areas?
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the upper and lower airways
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Inspired gas abruptly changes direction of flow at the ____point of the nasopharnyx.
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posterior
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The oropharynx and the laryngopharnyx are lined with what type of cells?
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non-cilitated stratifed squamous ephthelium
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The larynx is a cartilaginous cylindrical structure that acts as a valve on top of the trachea used for speech and to_____
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stop aspiration of soilids and liquides during swallowing and breathing
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The opeaning of the trachea is?
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The glottis
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The thyroid cartilage is also called the____.
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adams apple
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What is the eppiglottis shaped like?
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Thin flat leaf shaped
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What land mark is used intubation?
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vallecula
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Were does the vallecula?
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between the epiglottis and the tongue
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What part of the upper airway in infants is the narrowest?
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the cricoid
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What part of the upper airway is the narrowest in the adults?
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The glottis
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eppiglottitis is
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inflamation or swollen eppiglottis
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eppiglottitis is caused by?
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infection (croup) or trauma
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What kind of breath sound does eppiglottis make?
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stridor
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A tracheostomy is done were?
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1-3 cm below the cricoid cartlage
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Paralysis and edema caused by what?
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increased resistance to airway resistance
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larynospam occures when what enters the trachea?
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anything except air
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anatomical dead space is what?
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the conducting airways from the mouth and nose down to the terminal brochioles were no gas is exchanged
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Wasted ventilation is_____
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anatomical dead space
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emphysema cause what?
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more anatomical dead space
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how much anatomical dead space do we have?
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1 pound per ideal body weight or 2.2kg
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How do we figure out anatomical dead space for women?
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100 pounds for a 5ft women and add 5 pounds for every inch
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how do we fined the ideal body weight in men
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for a 5 ft man is 106 and then you add 6lbs for every inch after that
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were dose gas exchange occure?
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in the acinus
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What type of cells do the aalveoli have?
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type 1 and 2
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What do type one cells look like?
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flat
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What do type 2 cells look like?
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compacted polygonal shaped
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When is the diaphragm inactive?
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during quiet exhalation
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the fibers of the diaphram orginates from the lower ribs, sternum and the lower end of the __________
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sternum
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crural fibers originate from the _------- and the ________ of the lumbar vertabre.
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1st and 3rd
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The maxiumum that the diaphram can move down is
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6-10cm
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the diaphram moves how much durring normal breathing?
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1-2cm
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What side of the diaphram is higher the rt or the lft?
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the right
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Why is the rt side of the diaphram higher than the lft side?
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to allow the liver to be tucked under the bottom edge of the rib case
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The left side of the lung is lower because
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it allows room for the heart
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What are costophrinic angels?
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were the ribs meets the diaphram
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What are the two types of pleural effusion?
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Transudative and exudative
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What causes transudative pleural effusion?
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fluid leaking into pleural space, increased pressure or low protein
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What causes exudative effusion?
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blocked blood vessels inflamation injury or drug reaction
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What is pleural effusion?
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excess fluild in the pleural space that can impare breathing
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Alveorlar epithelium are highly permeable to gas but not to_
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liquid
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The spaces inbetween the membrain in the alveolar are?
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the interstium space
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What type of cell makes surfactant?
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Type 2 cells
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What is the purpose of the pressure gradients?
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Causes air to move in and out of the lungs and are responsible for keeping the lungs in an inflated state.
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What are the 3 important pressure gradients in ventilation?
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transpulmonary (PL)
transthoracic (Pw) transrespiratory (Prs) |
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What is the transpulmonary gradient (PL)?
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The difference between the pressure in the alveoli and the pleural space, and is responsible for maintaining alveolar inflation (PL = PA - Ppl)
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What is the transrespiratory gradient (Prs)?
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The difference between the atmosphere and the alveoli, and is responsible for the actual flow of gas into and out of the alveoli during breathing (Prs = Pl + Pw)
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What is the transthoracic gradient (Pw)?
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The difference between the pressure in the pleural space and the pressure at the body surface, and represents the total pressure required to expand or contract the lungs and chest wall. (Pw = Ppl - Pbs)
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What is a spirometer?
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The device used to measure volumes of air moving in and out of the lungs
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Residual volume RV
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Volume of air remaining in the lung after a maximal-effort expiration
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Expiratory reserve volume ERV
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Volume of air that can be exhaled with maximal effort from a resting (tidal) end-expiratory level
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Tidal volume TV or Vt
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volume of air normally inhaled or exhaled with each breath during resting, quiet breathing
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Inspiratory reserve volume IRV
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volume of air that can be inhaled with maximal effort from the tidal end-inspiratory level
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Total lung capacity TLC
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Volume of air in the lung after a maximal-effort inspiration; the sum of all volumes
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Inspiratory capacity IC
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Volume of air that can be inhaled with maximal effort from a resting (tidal) end-expiratory level; the sum of TV and IRV
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Vital capacity VC
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Maximum volume of air that can be exhaled after a maximal-effort inspiration; sum of IRV, TV, and ERV
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Functional residual capacity FRC
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Volume of gas remaining in the lung at the end of a normal tidal exhalation (relaxed ventilatory muscles); sum of
ERV and RV |
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Volume
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The amount of gas in a given lung "compartment" (one section)
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Capacity
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Two or more volumes
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Resistance
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recoil, elastance
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Compliance
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inflatable, distensible
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What is the main weaning parameter from a ventilator?
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RSBI - Rapid Shallow Breathing Index f(rr)/Vt
If it is >100 you usually do not pull tube |
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Cost of Breathing
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1 ml of O2/L of Vent
COPD 10 times as much O2 |