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103 Cards in this Set

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Upon leaving the bronchial walls of the capillary bed, O2 poor blood can go 2 ways(1) 25-33% drains thru true bronchial veins & into the right atrium and (2) the remaining 64-75% drains directly into the pulmonary veins. (2) does what to the pulmonary venous blood?
mixes poor O2 blood with well oxygenated blood
Normal anatomic shunting makes it so that systemic arterial blood can never have the same partial pressure of O2 as _____.
alveolar gas
Define anatomical shunting
The mixing of unoxygenated blood with oxygenated blood.
The ___ connections between bronchial & pulmonary circulation causes anatomical shunting( also called bronchopulmonary-arterial anastomoses).
vascular
Pulmonary venous blood is normally identical to ____ blood.
arterial
The _____ is the source of innervation for the lung airways.
autonomic nervous system(autonomic sensory & motor nerves)
Skeletal muscles of chest wall & diaphragm are innervated by the ___.
somatic nervous system
The ____ &___ are divisions of the autonomic system that control most of the body's visceral functions(soft organs of the thoracic & abdominal cavities).
sympathetic & parasympathetic
The paired ___ nerves supply motor inervation to the diaphragm. they originate from right and left cervical nervous plexus as branches of c3-c5.
phrenic
The ___ nerves are spinal nerves that innervate muscles between ribs & intercostal muscles.
intercostal
____ is the transmitter used in sympathetic innervation of the lungs.
norepinephrine
___ is the transmitter used in the parasympathetic innervation of the lungs.
acetylcholine
The external landmark for tracheal division into mainstem bronchi is the ___.
sternal angle(aka angle of louis)
This external angle marks where you must NOT go down to when doing compressions.
xiphoid process
The primary muscles for respiration are the ___ &___.
diaphragm & intercostals
The primary muscles for inspiration are the _____.
accessory muscles
The accessory muscles are ___ & ___.
Scalene & sternocleidomastoid
Movement of the ____ & _____ are responsible for pleural pressure changes.
lungs& chest
What is the (normal) pleural pressure value ?
755 mm Hg(negative under normal quiet breathing)
What is the (normal)pleural pressure value for inspiration & expiration?
-8 & -6
___(or distensibility) is the measure of the lung's opposition to inflation.
Compliance
What is the normal value for compliance?
.2L/cm H2O
____/_____ is the change in pressure required to produce a unit of volume change cm H2O/L. It is the mathematical reciprocal of compliance.
Resistance/elastance
Another term for airway resistance is RAW. ____ is the normal RAW in adults.
05-1.5 cm H2O/L/second
Surfactant forms a mono molecular layer over pulmonary alveolar surfaces, preventing alveolar collapse at lower lung volumes by ______.
reducing alveolar surface tension
Where is surfactant formed/produced by _____ and stored in lamellated bodies to be secreted onto the alveolar surface.
type II pneumocytes
Exchange of O2 with CO2 across capillary membranes by simple diffusion is called ___.
internal respiration
Exchange of gases from outside with the lungs(into the body) is called ___.
external respiration
How does a normal diaphragm move during inspiration (directional)?
down
How does a normal diaphragm move during expiration(directional)?
up
How much does a normal diapram move (distance)?
1-2cm(10 with max)
How does a floppy diaphragm move during inspiration & expiration?
the diaphragm decreases the AP diameter of the thoracic cavity on inspiration & moves very little on expiration( check expiration part again)
What diseases would cause problems with innervation of the diaphragm?
neuromuscular diseases and trauma
A huge part of clearance is the _______. The ciliated epithelial cells move in a forward motion, causing the trapping of foreign matter. The forward motion also moves the mucus upward & hopefully outward(this is mucokinesis)!
mucociliary escalator
The top layer of the airway tissue mucus is a ____ blanket, the next layer is the ___(water)layer where the tips of the ciliated epithelial cells "do the wave".
gel, sol
What does the upper airway consist of?
nose, oral cavity, pharynx and larynx
What are the functions of the nose ?
Air conditioning, filtering, warming and humidifying
What is another name for conchae?
turbinates
The function of the conchae or turbinates is to ______.
increase surface area
What types of cells are in the mucous of the lung?
immungolobiulins and inflammatory cells
The larynx marks the transition between what to areas?
the upper and lower airways
Inspired gas abruptly changes direction of flow at the ____point of the nasopharnyx.
posterior
The oropharynx and the laryngopharnyx are lined with what type of cells?
non-cilitated stratifed squamous ephthelium
The larynx is a cartilaginous cylindrical structure that acts as a valve on top of the trachea used for speech and to_____
stop aspiration of soilids and liquides during swallowing and breathing
The opeaning of the trachea is?
The glottis
The thyroid cartilage is also called the____.
adams apple
What is the eppiglottis shaped like?
Thin flat leaf shaped
What land mark is used intubation?
vallecula
Were does the vallecula?
between the epiglottis and the tongue
What part of the upper airway in infants is the narrowest?
the cricoid
What part of the upper airway is the narrowest in the adults?
The glottis
eppiglottitis is
inflamation or swollen eppiglottis
eppiglottitis is caused by?
infection (croup) or trauma
What kind of breath sound does eppiglottis make?
stridor
A tracheostomy is done were?
1-3 cm below the cricoid cartlage
Paralysis and edema caused by what?
increased resistance to airway resistance
larynospam occures when what enters the trachea?
anything except air
anatomical dead space is what?
the conducting airways from the mouth and nose down to the terminal brochioles were no gas is exchanged
Wasted ventilation is_____
anatomical dead space
emphysema cause what?
more anatomical dead space
how much anatomical dead space do we have?
1 pound per ideal body weight or 2.2kg
How do we figure out anatomical dead space for women?
100 pounds for a 5ft women and add 5 pounds for every inch
how do we fined the ideal body weight in men
for a 5 ft man is 106 and then you add 6lbs for every inch after that
were dose gas exchange occure?
in the acinus
What type of cells do the aalveoli have?
type 1 and 2
What do type one cells look like?
flat
What do type 2 cells look like?
compacted polygonal shaped
When is the diaphragm inactive?
during quiet exhalation
the fibers of the diaphram orginates from the lower ribs, sternum and the lower end of the __________
sternum
crural fibers originate from the _------- and the ________ of the lumbar vertabre.
1st and 3rd
The maxiumum that the diaphram can move down is
6-10cm
the diaphram moves how much durring normal breathing?
1-2cm
What side of the diaphram is higher the rt or the lft?
the right
Why is the rt side of the diaphram higher than the lft side?
to allow the liver to be tucked under the bottom edge of the rib case
The left side of the lung is lower because
it allows room for the heart
What are costophrinic angels?
were the ribs meets the diaphram
What are the two types of pleural effusion?
Transudative and exudative
What causes transudative pleural effusion?
fluid leaking into pleural space, increased pressure or low protein
What causes exudative effusion?
blocked blood vessels inflamation injury or drug reaction
What is pleural effusion?
excess fluild in the pleural space that can impare breathing
Alveorlar epithelium are highly permeable to gas but not to_
liquid
The spaces inbetween the membrain in the alveolar are?
the interstium space
What type of cell makes surfactant?
Type 2 cells
What is the purpose of the pressure gradients?
Causes air to move in and out of the lungs and are responsible for keeping the lungs in an inflated state.
What are the 3 important pressure gradients in ventilation?
transpulmonary (PL)
transthoracic (Pw)
transrespiratory (Prs)
What is the transpulmonary gradient (PL)?
The difference between the pressure in the alveoli and the pleural space, and is responsible for maintaining alveolar inflation (PL = PA - Ppl)
What is the transrespiratory gradient (Prs)?
The difference between the atmosphere and the alveoli, and is responsible for the actual flow of gas into and out of the alveoli during breathing (Prs = Pl + Pw)
What is the transthoracic gradient (Pw)?
The difference between the pressure in the pleural space and the pressure at the body surface, and represents the total pressure required to expand or contract the lungs and chest wall. (Pw = Ppl - Pbs)
What is a spirometer?
The device used to measure volumes of air moving in and out of the lungs
Residual volume RV
Volume of air remaining in the lung after a maximal-effort expiration
Expiratory reserve volume ERV
Volume of air that can be exhaled with maximal effort from a resting (tidal) end-expiratory level
Tidal volume TV or Vt
volume of air normally inhaled or exhaled with each breath during resting, quiet breathing
Inspiratory reserve volume IRV
volume of air that can be inhaled with maximal effort from the tidal end-inspiratory level
Total lung capacity TLC
Volume of air in the lung after a maximal-effort inspiration; the sum of all volumes
Inspiratory capacity IC
Volume of air that can be inhaled with maximal effort from a resting (tidal) end-expiratory level; the sum of TV and IRV
Vital capacity VC
Maximum volume of air that can be exhaled after a maximal-effort inspiration; sum of IRV, TV, and ERV
Functional residual capacity FRC
Volume of gas remaining in the lung at the end of a normal tidal exhalation (relaxed ventilatory muscles); sum of
ERV and RV
Volume
The amount of gas in a given lung "compartment" (one section)
Capacity
Two or more volumes
Resistance
recoil, elastance
Compliance
inflatable, distensible
What is the main weaning parameter from a ventilator?
RSBI - Rapid Shallow Breathing Index f(rr)/Vt
If it is >100 you usually do not pull tube
Cost of Breathing
1 ml of O2/L of Vent
COPD 10 times as much O2