The Progession of Man-Made Organs Essay

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Beginning in 1980, scientists have been trying to find a solution to the progressing problem of organ transplants. Many concerns come with transplanting an organ into the body; the two major issues are a lack of donors and a high rejection rate. A proposed solution to the rising issue is growing artificial organs in a lab. As technology advances, researchers are becoming increasingly closer to successfully growing a functioning organ that can be transplanted into a human body.
When researchers first began the climb to successfully grow internal organs in a lab, many barriers needed to be overcome; the first being growing ticker tissues. In the article ā€œLab-Grown Organs Begin to Take Shape,ā€ Robert Langer, inspired by the branching of
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The transplantation of an engineered lung tissue into a mammal was a big movement in the field of tissue engineering because it was the first time that a lab-grown tissue effectively performed its function inside a mammal. Around the same time that Niklason and her team transplanted a functioning tissue, James Wells and a team of scientists grew the first ever complex organ. The team grew 3D tubes of tissue by adding a protein to stem cells that eventually made the cells distinguish themselves into those of a gastrointestinal tract. After culturing the tissue for over a month, the team noticed that the tissue had produced cell families necessary to gastrointestinal health, which meant that the tissue could now perform as a complex organ. The necessary cell families included those that absorb nutrients and secrete mucous, hormones, and enzymes (Weaver 2010). Growing the intestinal organ was a big step in the field of tissue engineering because it was the first time that scientists were able to get stem cells to differentiate themselves and grow into a complex organ.
While different organs were repeatedly and successfully being engineering, the engineering of a heart was tried multiple times but continuously failed until a group of biomedical engineers from all over the US put their minds together to produce the first bioartificial heart. They first developed a way in which healthy cells adhered to a biomaterial

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