Thymus Fontanesi Case Study

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Development and evaluation of an antimicrobial formulation containing the essential oil of Thymus fontanesii Boiss. & Reut .

Mebarki Noudjoub , Nabiev Mohamed2, Chader Henni3, Ziane Henifa4, Fazouane Fethia1

1 Food Technology Research Laboratory, FSI, M’hamed Bougara University, Boumerdès 35000, Algeria
2 Department of Chemical and Pharmaceutical Process Engineering, FHC, M’hamed Bougara University, Boumerdès 35000, Algeria
3 National Laboratory of Control of Pharmaceuticals Products (NLCPP), Algiers, Algeria.
4 Microbiology Laboratory, CHU Mustapha, Algiers, Algeria.

A b s t r a c t
The present study aim to evaluate the in vitro antimicrobial activity of essential oil (EO) of Thymus fontanesii Boiss. & Reut and a formulation containing
…show more content…
The extraction yield was about 3.5 ± 0.1% (v/w) , which is higher than those found by Haddouchi et al. 2009 and Mohammedi et al. 2010 (2%, 3.09% respectively), for the same species of thyme harvested in Mostaganem province and Tlemcen area (Algeria). Furthermore, it was higher than that obtained from other species of thyme from Algeria considered as economically important for essential oils production, such as Thymus lanceolatus with 0.9% (Khadir et al. 2013) and Thymus dreatensis with 2.1% (Ferhat et al. …show more content…
Pallavi V. Pople and Kamalinder K. Singh. 2006. Development and Evaluation of Topical Formulation Containing Solid Lipid Nanoparticles of Vitamin A. AAPS PharmSciTech. 7 (4) Article 91
29. Pinto E, Pina-Vaz C, Salgueiro L, Gonςalves MJ, Costa-de-Oliveira S, Cavaleiro C, Palmeira1A, Rodrigues A and Martinez-de-Oliveira J.2006. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. Journal of Medical Microbiology.55:1367–1373
30. Raghavamma STV, Anjali MV, Amrutha NN, Hemalatha T , Nadendla RR.2016. Assessment of Efficacy and Safety of Newly Formulated Natural Sun Protective Cream. IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS). 11(5): 119-124
31. Viswanad V, Aleykutty1 NA, Jayakar B, Zacharia SM, Thomas L.2012. Development and evaluation of antimicrobial herbal formulations containing the methanolic extract of Samadera indica for skin diseases. J. Adv. Pharm. Tech. Res. 3(2): 106-111. DOI: 10.4103/2231-4040.97285.
32. Viswanad V, Zachariah SM, Sathi A, Aleykutty1 NA. 2015. Development of phytovesicles containing triterpenoids from Samadera indica. Pharmacognosy Research. 7(2): 176-183. DOI:

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