The Sickle Cell Disease

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Sickle Cell Disease is a blood disorder that’s inherited and affects almost 100,00 folks in the United States . Red blood cells contain hemoglobin which is a protein that carries oxygen in the blood . Normal red blood cells are flexible and round which allows body . The sickle cell disease causes red blood cells to form a cresent shaped red blood cells to break away easily causing anemia . Instead of the normal 120 days the sickle red blood cells live 10 -20 days . The damaged sickle red blood cells stick to the walls of blood vessels ,clump together and blocks blood flow . They can cause permanent damage to the bones ,kidneys ,lungs , liver ,heart …show more content…
Its found in racial group and other ethnics also including folks Central America , the Caribbean , India , and the Mediterranean countries .
The cause for Sickle Cell Disease is by genetic abnormality in the hemoglobin genes , and the results in the production of sickle hemoglobin .When oxygen is released from sickle hemoglobin it will stick together and form long rods that damage and causes the red blood cells shape to change .Symptoms of sickle cell disease is caused by the sickle red blood cells .Although its not contagious children are born with the sickle cell disease.
If a child inherits two sickle hemoglobin genes one from each parent then this will occur. In the United States about 2000 babies are born with sickle cell disease yearly . Those who inherit just sickle hemoglobin gene are sickle cell trait carries and do not have anemia or painful Sickle Cell Crisis .Although they have a slighty higher incidence of different conditions such as urinary tract infections or blood in the urine
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Severe illness with chest pain , fever ,and difficult breathing can be caused by sickle red blood cells in the lungs .Liver , Spleen , Kidneys ,Heart and Bones can also be caused by Sickle Cell Disease.
Even within the dame family the severity and symptoms vary greatly from person to person .

When examined under a microscope from a blood sample sickle shaped red blood cells can can be seen . The Sickle Cell Disease is diagnosdd by hemoglobin electrophoresis which is a blood test , which measures the amount abnormal sickle hemoglobin . To determine whether the person is a carrier ( sickle cell trait ) or has the Sickle Cell Disease is determined by the amount of sickle red blood cells or clumps of abnormal sickle hemoglobin when oxygen is removed from the blood can be determined by a rapid screening test . Which is les commonly used . This is because its hard to distinguish between Sickle Cell Trait and Sickle Cell Disease . By examining the DNA of fetal cells obtained by chronic villus sampling or amniodentesis by prenatal testing for Sickle Cell

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