Research Article Critique on Alzheimer's Disease Essay
April 18, 2012
Research Article Critique 1
1. Brodaty, H., Ames, D., Snowdon, J., Woodward, M., Kirwan, J., Clarnette, R., & ... Greenspan, D. (2005). Risperidone for psychosis of Alzheimer's disease and mixed dementia: results of a double-blind, placebo-controlled trial. International Journal of Geriatric Psychiatry, 20(12), 1153-1157.
2. The purpose of this study is to evaluate the efficacy and safety of low dose risperidone in treating psychosis of Alzheimer’s disease (AD) and mixed dementia (MD) in a subset of nursing-home residents who had dementia and aggression and who were participating in a randomized placebo-controlled trail of risperidone for aggression.
3. The problem is …show more content…
7. About the Variables: a. The independent variable in the study would be the patients taking the placebo pills for psychosis or aggression behavior. The dependent variables of the study would be the patients taking the low-dose risperidone to help control the psychosis and aggressive behavior. These dependent variables are also known as the effect of taking the medication. The independent and dependent groups are directly stated.
b. No, extraneous variables mentioned to my knowledge of the study. c. Yes, the variables are defined to the extent that replication of the study would be possible. 8. About the Sample: a. The sample size was a total of 337 patients taking the study and 93 patients with AD or MD (46 risperidone and 47 placebos). Yes, the sample size was large enough to show significant difference.
b. The 93 patients with psychosis of AD were predominantly female and white. The subjects were all patients from nursing homes residents and were mainly white females. c. The sampling technique used by the researchers the patient had to meet the requirements for the main trial which were a diagnosis of Alzheimer’s disease, mixed dementia, age >55 years, and reside in nursing homes and long term care