Penicillin Azithromycin Essay

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Chemotherapy
Chemotherapy sometimes involves the use of antibiotic drugs since it is basically defined as the use of chemicals or medication to treat diseases. However, this term is used to specifically refer to the medical processes that are geared toward the destruction of cancer cells. In some cases, the process involves using antibiotics and other medications to treat certain infections or illnesses that may arise as a result of the clinical processes toward destruction of cancer cells. Some of the drugs that may be used in such instances include penicillin, gentamicin, azithromycin, doxycycline, co-trimoxazole, and ciprofloxacin. These drugs have varying mechanism of action, clinical uses, and adverse effects.
Penicillin
Penicillin
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The prevalent popularity of the potency of this drug stems from its gradual elimination from the body that enables the treatment of infections for several days of single administration on a daily basis. As previously mentioned, this new agent is derived from erythromycin through a process that involves incorporating nitrogen atom into the lactone ring, which makes the lactone ring to become 15-membered. The mechanism of action of azithromycin is inhibiting bacteria from developing through interfering with protein synthesis. While this mechanism of action is similar to the one of gentamicin, it differs in the fact that azithromycin binds 50S subunit of the bacterial ribosome. Even though this contributes to prevention of the translation of mRNA, the drug’s mechanism of action does not affect the synthesis of nucleic …show more content…
Co-trimoxazole Co-trimoxazole is an antibiotic drug that has been used for five decades for treatment of infections in HIV infected individuals and malaria. The drug is regarded as inexpensive, which has contributed to its nearly universal availability and broad clinical range of use. Generally, this antibiotic is a mixture of trimethoprim and sulfamethoxazole (Brown, 2013, p.1). Despite its use in treatment of malaria and some HIV-related infections, co-trimoxazole is renowned as an antibacterial drug. Since it is a mixture of trimethoprim and sulfamethoxazole, the mechanism of action of this antibiotic is similar to that of trimethoprim and sulfamethoxazole. This implies that co-trimoxazole works through preventing the synthesis of tetrahydrofolic acid and bacterial dihydrofolate reductase. The combination of the two components of the drug works through preventing successive processes in folate

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