HAART: A Literature Review

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The findings of this literature review demonstrate that a variety of factors have influenced adherence towards HAART. The use of critical analysis and CASP tools to the chosen 10 articles has addressed a number of weaknesses and strengths for each article, and has projected two consistent themes; complexity of drug regimens and symptom experiences of HARRT. As previously discussed and outlined (see appendix 3), the evidence within both themes is of good quality, however, the prevalence of a number of limitations questions the credibility and validity of some results findings. Of the two themes, the complexity of drug regimens is arguably more informative of the two, as it used a range of research methods including
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(2011) discovered that HAART adherence was higher after delivering individualised counselling (p = 0.023) as compared to those who did not receive counselling. Another study by Ribeiro, et al. (2015) had statistically significant findings after delivering an individualised educational intervention, stating that non adherence dropped by 21.6% (p=0.002). The authors concluded that the programme seems to be feasible and efficient, improving adherence to HAART. However, 41% of the participants in a study carried out Ribeiro, et al. (2015) were non-compliant with the full schedule, and missed at least one or more sessions; this can be viewed as a potential barrier towards implementing this change. The authors of this study argued that the reason for this non-adherence may have been influenced by demographic factors, citing that the majority of the study population were all professionals and/or lived far. Despite these limitations, the CASP (2014) tool critically appraised the study and found plenty of strengths, such as its large sample size and ethics approval; which can arguably endorse the study as a credible source.
The National AIDS Trust (2010) points out the benefits of individualised adherence counselling stating that it can help to diminish the patient’s psychological distress. Based on this evidence, it can be argued that adherence counselling from a clinical perspective can be seen as
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Gamel et al. (2001) explain how different all patients respond to their illnesses, treatment and adherence to medication based from their previous unique illness experience and beliefs. This is supported by the NHS Institute for Innovation and Improvement, (2008a) citing that individual behaviour in relation to enhancing and maintaining their adherence is modelled around their experiences of the disease process or intervention, and will thus can give a unique perspective; providing valuable insight resulting in better service delivery. This is supported by the Francis Report recommendations that “…the single most significant factor is placing people at the centre of the NHS…” (Morton et al, 2015, p.30). On the contrary, Rycroft-Malone et al (2004) states that little is known about the contribution that patient experience adds, or the role it

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