Endocrine Tumors

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1.) According to Jonbarron.org, an endocrine tumor is a mass that begins in the parts of the body that produce and release hormones. The neoplastic cells secrete the hormone normally produces by the cells of the gland, but they are not responding to negative feedback which controls mechanisms so hormones re secreted in an inappropriate and excessive manner. Because an endocrine tumor develops from cells that produce hormones, the tumor itself can produce hormones and cause serious illness.

2.) Hormones secreted by the adrenal medulla are, epinephrine or also known as adrenaline. This hormone responds to stress by increasing your heart rate and rushing blood to the muscles and brain. It also raises your blood sugar level by helping convert
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4.) According to Endocrinediseases.org, Pheochromocytoma is a disease where too much epinephrine is being made by an adrenal tumor. They grow within the center part of the adrenal gland, which is the adrenal medulla.

5.) Hypertension is the common symptom of pheochromocytoma according to the website, Sharecare.com. In addition, the classic three signs are headaches, palpitations and sweating. Difficulty breathing, weakness, and panic attack-type symptoms can also
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8.) Diaphoresis or sweating due to ectopic catecholamine is a symptom of a pheochromocytoma. The majority of sweat glands in the body are innervated by sympathetic cholinergic neurons. Sympathetic postganglionic neurons usually secrete norepinephrine and are called sympathetic adrenergic neurons. However, when sympathetic postganglionic neurons innervate sweat glands, they secrete acetylcholine. Sweat glands and some blood vessels are innervated by sympathetic cholinergic neurons.

9.) Patients should be tested to see if they have too much catecholamine (epinephrine/ norepinephrine) in their system. Catecholamine last only a short time and are quickly broken down by the body into molecules called metanephrine. Metanephrine last much longer and are easier and more accurate to measure than catecholamine. Catecholamine and metanephrine may be measured in the blood or in a 24-hour collection of urine. Depending on the patient's age, family history, and other factors, plasma and urine tests will be ordered. Levels that are at least twice the upper limit of normal mean that the patient is almost certain to have a pheochromocytoma. It is important to note that certain medications can interfere with these tests, including some antidepressants and other medications for psychiatric diseases and high blood

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