According from the article the locus coeruleus helps the maintain the sympathetic effect the stress. Moreover, the locus coeuleus actives by the stress and respond the increasing the norepinephrine secretion. The studies had been done by Raskind shows that norepinephrine and neuropeptides has major part for the long term outcomes of the stress exposure because the neurons secrete the hormone noreponephine. Based on the research it is found the neurons in locus coeruleus is important and sufficient to initiate stress-induced anxiety. Moreover the researchers also found that a small protein that released while the stressful-time, corticopropin releasing hormone (CRH) is modulates the specific neuronal activity of locus coeruleus. Therefore, the
