Coronary Heart Disease Risk Analysis

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The article titled “Do changes in traditional coronary heart disease risk factors over time explain the association between socio-economic status and coronary heart disease?” was written by Peter Franks, Paul C Winters, Daniel J Tancredi and Kevin A Fiscella to examine whether changes in Coronary heart disease risk factor overtime explain the association between status and coronary heart disease due to its relevant risk assessment in clinical decision making. It is unknown whether changes in Framingham risk score variables over time explain the association between SES and coronary heart disease. However, socioeconomic status does predicts coronary heart disease independently of the traditional risk factors included in the Framingham risk score. …show more content…
There were 15,732 participants in the study. Four US communities The Field centers were randomly selected and a sample of approximately 4,000 individuals aged 45-64 years were recruited in Forsyth County, North Carolina, Jackson, Mississippi , Minneapolis suburbs, Minnesota , and Washington county, Maryland. First, participants were examined to yield medical and socio-demographic data and follow ups were on-going, every 3 years. The participants would fast 12 hours before their examination visits. The lipid testing was done by the Central Lipid Laboratory in Houston, Texas. When it comes to total cholesterol, that was determined by enzymatic methods with high density lipoprotein cholesterol measured after dextran-magnesium precipitation. Systolic blood pressure was measured three times, five minutes apart using a random zero sphygmomanometer while participants were seated, and the average of the measures was used for the analysis. Information on each participant smoking status and antihypertensive medication use were obtained by self-report. Data regarding coronary heart disease events and risk factors were collected through annual telephone interviews, surveys of hospital discharge data, and death certificates from state vital statistics

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