While PTC carries the best prognosis among the variable types of thyroid carcinomas with survival rates ranging from 92% to 95% at 5 years and from 89% to 90% at 10 years,17 the effect of cervical nodal metastasis on survival is difficult to assess.18 In the absence of a survival benefit, potential morbidities and medical economics, the value of the conventional use of neck dissection is not accepted.18 PCND in clinically node-negative DTC patients remains controversial.19
Patients with PTC are usually young, and cervical metastases are not uncommon.20 The mean age of our patients was 30±2.3 years, which is comparable to other studies.21,22 The female to male ratio was also similar to previous studies as 3.2:1.23
In accordance with previous studies, CND revealed metastasis in 43% of patients experienced neck dissection.24 Also, other studies recorded this occult metastasis to be between 40 and 90%.25 So many surgeons consider the necessity of CND for PTC patients because the high rate of CN metastasis. …show more content…
However, in a study of patients 2 cm) were significantly associated with CN metastasis.27 Ito et al. reported that PTC of >2 cm was the strongest independent risk factor for both microscopic central and lateral LN metastasis.34 The presence of LN metastasis has been recorded to be 2-6 fold higher in patients with tumors of >4 cm in comparison with smaller tumors.35 In our study, CN metastasis was more frequent in patients with tumor size >2 cm and detected in 77% of patients, in comparison to patients with tumor size ≤2cm CN metastasis was detected in 53% of patients (P=0.007). Multivariate logistic regression analysis revealed that tumor size >2 cm was an independent predictor of CN metastasis in patients with N0
Patients with PTC are usually young, and cervical metastases are not uncommon.20 The mean age of our patients was 30±2.3 years, which is comparable to other studies.21,22 The female to male ratio was also similar to previous studies as 3.2:1.23
In accordance with previous studies, CND revealed metastasis in 43% of patients experienced neck dissection.24 Also, other studies recorded this occult metastasis to be between 40 and 90%.25 So many surgeons consider the necessity of CND for PTC patients because the high rate of CN metastasis. …show more content…
However, in a study of patients 2 cm) were significantly associated with CN metastasis.27 Ito et al. reported that PTC of >2 cm was the strongest independent risk factor for both microscopic central and lateral LN metastasis.34 The presence of LN metastasis has been recorded to be 2-6 fold higher in patients with tumors of >4 cm in comparison with smaller tumors.35 In our study, CN metastasis was more frequent in patients with tumor size >2 cm and detected in 77% of patients, in comparison to patients with tumor size ≤2cm CN metastasis was detected in 53% of patients (P=0.007). Multivariate logistic regression analysis revealed that tumor size >2 cm was an independent predictor of CN metastasis in patients with N0