Antibiotic Resistant Bacteria Are Becoming An Increased Problem

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Literature Assignment #2

According to the Infectious Diseases Society of America (IDSA), antibiotic-resistant bacteria are becoming an increased problem in hospitals and communities due to the lack of antibacterial options currently available. Throughout the world, many Gram-positive and Gram-negative pathogens are growing more resistant to antibiotics currently on the market. The goal of this journal article is to raise awareness for the global antibiotic crisis and to hopefully encourage the community and legislative to raise funds in order to increase antibiotic production. In order for the IDSA to determine antibacterial candidates that would be a good match for the antibiotic-resistant bacteria, a variety of sources were looked over. They focused on sources that showed antibacterial options in phase 2 or later development that could be used orally or intravenously for ease of use in clinical aspects. The “ESKAPE” pathogens that are currently causing the majority of infections and are resistant to current antibiotics are Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa, and Enterobacter species. According to the Centers for Disease Control and Prevention (CDC), the rate at which people are being infected has dramatically increased over the years. The increasing rates of infections are caused by methicillin-resistant S. aureus (MRSA), vancomycin-resistant E. faecium (VRE), and fluoroquinolone-resistant…

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