The main animal models for these studies are mice; its use as an animal model has provided outstanding information about the mechanism underlying the state of pain. (Graham et al., 2012) Pain assessment studies apply knowledge from different scientific areas such as physiopathology, psychology, ethology and even social areas for future regulations, among others. From a genetic and molecular point of view, the research done in mice as animal model of pain has even lead to the creation of a gene database that lists publications of genes and their protein products in pain processing in transgenic mice (LaCroix-Fralish et al., 2007). However, there is a necessity for objective and reliable pain assessment methods that can be used during surgical procedures, experimental situations, or on field
The main animal models for these studies are mice; its use as an animal model has provided outstanding information about the mechanism underlying the state of pain. (Graham et al., 2012) Pain assessment studies apply knowledge from different scientific areas such as physiopathology, psychology, ethology and even social areas for future regulations, among others. From a genetic and molecular point of view, the research done in mice as animal model of pain has even lead to the creation of a gene database that lists publications of genes and their protein products in pain processing in transgenic mice (LaCroix-Fralish et al., 2007). However, there is a necessity for objective and reliable pain assessment methods that can be used during surgical procedures, experimental situations, or on field