A physiological phenomenon that is unavoidable and affects all organisms is aging. Aging is responsible for causing the loss of cellular homeostasis catalyzing the decline of cellular function and ultimately end in cell death. Advanced aging globally affects the cell, including essential organelles such as the mitochondrion and actin cytoskeleton. Mitochondria are the primary energy source for the cell, while the actin cytoskeleton is a dynamic system that is an integral part of cellular structure maintenance and organization. As one can easily see, the functional decline of both actin and mitochondria can cause total cellular dysfunction and cell death.
